Search results for " STANDARDS"
showing 10 items of 343 documents
Emerging approaches to estimate retention factors in high performance liquid chromatography.
2004
The retention factor is one of the most universally used parameters in chromatography. The errors associated with the conventional ways to determine the retention factor of compounds in liquid chromatography are studied and compared with those corresponding to new approaches. The later avoid the use of extra-column time and hold-up time values, which have proven to be tedious and ambiguous. Simulations and real data, used to examine the accuracy of four different approaches (two classic and two new), suggest that the new approaches could be considered more satisfactory than the classic ones.
Development of standard operation procedures for the manufacture of n-octadecyl bonded silicas as packing material in certified reference columns for…
2004
The development of standard operation procedures for the manufacture of a n-octadecyl bonded spherical silica packing from partially condensed tetraethoxysilane as silica source is described. The synthesis comprises five intermediate products and six synthesis steps which were examined according to their reproducibility and robustness. The results led to the optimisation of the manufacturing process for a n-octadecyl bonded silica. Correlations were drawn between the dynamic viscosity of the poly(ethoxy)siloxane (PES), the synthesis parameters, the resulting pore structural properties and particle size distribution of the silicas. Validated procedures were developed to manufacture spherical…
Identification of diterpenes in canvas painting varnishes by gas chromatography-mass spectrometry with combined derivatisation.
2004
A derivatisation method that combines the formation of ethyl esters from the carboxylic groups and trimethylsilyl ethers from hydroxyl groups of the components of diterpenic resins is presented in this paper. This methodology involves two experimental steps: (1) formation of ethyl esters using ethyl chloroformate; and (2) the esterified compounds are lead to react with trimethylsilylimidazole to form the corresponding trimethylsilyl ethers. The main advantage of the proposed method is the possibility of performing simultaneously the analysis of amino acids from proteins, fatty acids from drying oils, and diterpenic compounds from natural resins usually found in works of art. This methodolog…
Influence of oscillating main flow on separation efficiency in asymmetrical flow field-flow fractionation.
2021
The steadily rising interest in the investigation of interactions between nanomaterials and biological media has also led to an increasing interest in asymmetrical flow field-flow fractionation (AF-FFF). The biggest strength of AF-FFF is the possibility to alter the flow profiles to suit a specific separation problem. In this paper, the influence of an oscillating main flow on the separation efficiency of AF-FFF is investigated. Such oscillations can e.g. be caused by the main pump To investigate the influence of such flow conditions on the separation efficiency in AF-FFF systematically, different oscillation profiles were applied and their influence on the elution profile and the retention…
Rapid and simultaneous high-performance liquid chromatography assay of polyamines and monoacetylpolyamines in biological specimens
2000
A rapid, resolutive and reproducible reversed-phase high-performance liquid chromatography (RP-HPLC) method was developed for polyamines and acetylpolyamines by adopting pre-column derivatization with benzoyl chloride. In a single run lasting less than 15 min ten polyamines were separated as well as traces of benzoic acid, methylbenzoate and benzoic anhydride. These contaminants, produced during the derivatization reaction, were almost all eliminated by washing steps envisaged in the same procedure. This simple and sensitive method can be applied to routine determination of polyamines in biological samples. A fine application of this procedure to the determination of endogenous content of p…
HL7v3 CDA Rel.2 Patient Summary and Chronic Care Model: Localization experience and GP/HS Integration Project
2010
The localization experience for the Patient Summary, based on the Health Level Seven Version 3 (HL7v3) Clinical Document Architecture, Release 2 (CDA Rel.2), is presented. An overview of the Chronic Care Model (CCM) is introduced with particular attention to the clinical information systems, in order to organize patient and population clinical data by sharing information among healthcare providers in management of chronic diseases. We propose, as case study, a project for the integration of various services for General Practitioners (GP) and Hospital Specialists (HS), accessing the Electronic Health Record (EHR), implementing the Patient Summary and managing the exchange of Chronic Care med…
Labour market response to globalisation: spain, 1880-1913
2010
Abstract This paper analyses the impact of globalisation (trade and migration) on the Spanish labour market between 1880 and 1913 by examining the influence that globalisation factors had on agricultural and industrial wages. Our results show that the nineteenth century grain invasion had a negative impact on agricultural wages, whereas the fall in wheat prices did not benefit industry workers. We also found that migration pushed up real agricultural and industrial wages. As agriculture was the main sector in the economy, the final impact was a wage decrease. The negative impact of trade on agricultural and industrial labour markets partly explains the trade policy response of “integral pro…
Validating retinal fundus image analysis algorithms: issues and a proposal.
2013
This paper concerns the validation of automatic retinal image analysis (ARIA) algorithms. For reasons of space and consistency, we concentrate on the validation of algorithms processing color fundus camera images, currently the largest section of the ARIA literature. We sketch the context (imaging instruments and target tasks) of ARIA validation, summarizing the main image analysis and validation techniques. We then present a list of recommendations focusing on the creation of large repositories of test data created by international consortia, easily accessible via moderated Web sites, including multicenter annotations by multiple experts, specific to clinical tasks, and capable of running …
Measuring the weather’s impact on MAC layer over 2.4GHz outdoor radio links
2015
The weather s impact on the performance of a radio link at the 2.4 GHz ISM (Industry, Scientific and Medical) band had not been yet studied in great detail up to now as it is generally believed that the ultra-high frequency band is not significantly affected by weather conditions. However, our study shows significant correlations between meteorological variables and control frame errors at MAC (Medium Access Control) layer of the IEEE 802.11b/g standard. This study is performed over an outdoor radio link setting which has been monitored for several months. Moreover, we check if link distance and so modulation scheme and data rate are also decisive features of such impact. Our real scenario …
Concordance Analysis
2011
Background In this article, we describe qualitative and quantitative methods for assessing the degree of agreement (concordance) between two measuring or rating techniques. An assessment of concordance is particularly important when a new measuring technique is introduced.