Search results for " Simulation"
showing 10 items of 4034 documents
Importance sampling correction versus standard averages of reversible MCMCs in terms of the asymptotic variance
2017
We establish an ordering criterion for the asymptotic variances of two consistent Markov chain Monte Carlo (MCMC) estimators: an importance sampling (IS) estimator, based on an approximate reversible chain and subsequent IS weighting, and a standard MCMC estimator, based on an exact reversible chain. Essentially, we relax the criterion of the Peskun type covariance ordering by considering two different invariant probabilities, and obtain, in place of a strict ordering of asymptotic variances, a bound of the asymptotic variance of IS by that of the direct MCMC. Simple examples show that IS can have arbitrarily better or worse asymptotic variance than Metropolis-Hastings and delayed-acceptanc…
Weak pseudo-bosons
2020
We show how the notion of {\em pseudo-bosons}, originally introduced as operators acting on some Hilbert space, can be extended to a distributional settings. In doing so, we are able to construct a rather general framework to deal with generalized eigenvectors of the multiplication and of the derivation operators. Connections with the quantum damped harmonic oscillator are also briefly considered.
Tridiagonality, supersymmetry and non self-adjoint Hamiltonians
2019
In this paper we consider some aspects of tridiagonal, non self-adjoint, Hamiltonians and of their supersymmetric counterparts. In particular, the problem of factorization is discussed, and it is shown how the analysis of the eigenstates of these Hamiltonians produce interesting recursion formulas giving rise to biorthogonal families of vectors. Some examples are proposed, and a connection with bi-squeezed states is analyzed.
On the function of modified nucleosides in the RNA world.
1998
Presumably ribosome and transfer RNA (tRNA) evolved from a pre-existing function in the RNA stage of life and were secondarily adapted for protein synthesis. Various possible initial functions of the primitive ribosome (protoribosome) have been suggested. The initial function of the primitive ribosome and primitive genetic translation would have been quite similar. It is possible that, initially, both functions coexisted in the protoribosome. Given that the three-dimensional structure of ribosomal RNAs shows only minor variations throughout time, it is, then, most likely that present ribosomes can still recall (remember) the most important parts of the mechanism of their initial function. A…
Macroscopic Dynamic Effects of Migrations in Patchy Predator-prey Systems
1997
Abstract Different mechanisms at the behaviourial or physiological levels determine many properties of predator-prey systems at the population level. In this paper, we present a method of obtaining complex predator-prey dynamic models from models at a detailed, behaviourial level of description. We consider a multi-patch predator-prey model, the dynamics of which contains two time-scales: a fast one, associated with migrations between patches, and a slow one, on which interactions, reproduction and mortality occur. We use methods of perturbation theory in order to aggregate the multi-patch system into a reduced system of two differential equations for the total prey and predator populations…
Mixture Analysis in Biology: Scope and Limits
1998
Modular Structures on Trace Class Operators and Applications to Landau Levels
2009
The energy levels, generally known as the Landau levels, which characterize the motion of an electron in a constant magnetic field, are those of the one-dimensional harmonic oscillator, with each level being infinitely degenerate. We show in this paper how the associated von Neumann algebra of observables displays a modular structure in the sense of the Tomita–Takesaki theory, with the algebra and its commutant referring to the two orientations of the magnetic field. A Kubo–Martin–Schwinger state can be built which, in fact, is the Gibbs state for an ensemble of harmonic oscillators. Mathematically, the modular structure is shown to arise as the natural modular structure associated with the…
From deterministic cellular automata to coupled map lattices
2016
A general mathematical method is presented for the systematic construction of coupled map lattices (CMLs) out of deterministic cellular automata (CAs). The entire CA rule space is addressed by means of a universal map for CAs that we have recently derived and that is not dependent on any freely adjustable parameters. The CMLs thus constructed are termed real-valued deterministic cellular automata (RDCA) and encompass all deterministic CAs in rule space in the asymptotic limit $\kappa \to 0$ of a continuous parameter $\kappa$. Thus, RDCAs generalize CAs in such a way that they constitute CMLs when $\kappa$ is finite and nonvanishing. In the limit $\kappa \to \infty$ all RDCAs are shown to ex…
Change-points detection for variance piecewise constant models
2011
A new approach based on the fit of a generalized linear regression model is introduced for detecting change-points in the variance of heteroscedastic Gaussian variables, with piecewise constant variance function. This approach overcome some limitations of both exact and approximate well-known methods that are based on successive application of search and tend to overestimate the real number of changes in the variance of the series. The proposed method just requires the computation of a gamma GLM with log-link, resulting in a very efficient algorithm even with large sample size and many change points to be estimated.
On the dimerization of the primitive tRNAs: implications in the origin of genetic code.
2002
RNAs that catalyse their own aminoacylation have been recently selected in vitro. These findings support the notion that the primitive aminoacyl-tRNA synthetases may have been RNAs. In this paper, we propose a structural model for the first aminoacyl-tRNA synthetase consisting of an RNA complex formed between two primitive tRNA molecules through two intermolecular loop-strand interactions, and with implications in the origin of the genetic code.