Search results for " Small Cell"

showing 3 items of 93 documents

Synchronous Two Distinct Neuroendocrine Lung Cancer Lesions

2015

Synchroniczne nowotwory płuc są rzadką chorobą, a prezentowany przypadek to pierwszy opublikowany opis jednoczesnego wystąpienia dwóch pierwotnych neuroendokrynnych raków płuca zlokalizowanych w jednym płacie. Przedstawiono przypadek 55-letniej pacjentki z dwoma pierwotnymi, odrębnymi neuroendokrynnymi rakami płata górnego płuca prawego. Pacjentka została przyjęta na oddział chirurgii klatki piersiowej w celu diagnostyki dwóch cieni okrągłych płuca prawego (o średnicy 11 i 19 mm) uwidocznionych na zdjęciu RTG klatki piersiowej wykonanym trzy miesiące wcześniej. Przy przyjęciu pacjentka nie prezentowała żadnych objawów związanych ze zmianami w płucu. Dalsze badania obrazowe wykazały zmiennoś…

Pulmonary and Respiratory MedicinePathologymedicine.medical_specialtyLung NeoplasmsLung biopsySmall-cell carcinomasynchronous primary lung cancerNeoplasms Multiple PrimarymedicineHumansCarcinoma Small CellLung cancerdrobnokomórkowy rak płucalarge cell neuroendocrine carcinomasmall cell carcinomaEtoposideCisplatinLungbusiness.industrywielkokomórkowy neuroendokrynny rak płucaNeoplasms Second PrimaryMiddle Agedmedicine.diseaseCarcinoma Neuroendocrinemedicine.anatomical_structureCardiothoracic surgeryFemaleProphylactic cranial irradiationTomography X-Ray Computedbusinesssynchroniczny rak płucamedicine.drugAdvances in Respiratory Medicine
researchProduct

Moving osimertinib to first-line: the right “strategy” in the chessboard of epidermal growth factor receptor-mutated non-small cell lung cancer?

2018

In the N Engl J Med , Soria and colleagues have recently reported the results of the phase III randomized FLAURA trial (1), comparing osimertinib with first generation epidermal growth factor receptor-tyrosine kinase inhibitors (EGFR-TKIs) gefitinib or erlotinib in treatment-naive patients with advanced non-small cell lung cancer (NSCLC) and activating EGFR -mutations.

Pulmonary and Respiratory Medicinebiologybusiness.industryKinasemedicine.diseaserespiratory tract diseases03 medical and health sciences0302 clinical medicineGefitinibEditorialEpidermal growth factor030220 oncology & carcinogenesisCancer researchbiology.proteinMedicineOsimertinibHuman medicine030212 general & internal medicineEpidermal growth factor receptorNon small cellErlotinibbusinessLung cancerneoplasmsmedicine.drug
researchProduct

Oral vinorelbine in the treatment of non-small cell lung cancer: rationale and implications for patient management.

2007

Vinorelbine is an established treatment for advanced non-small cell lung cancer (NSCLC), both as a single agent and in combination chemotherapy. Recently, an oral form of this agent has been developed. Before accepting an established agent in a different administration form, rigorous testing is required to answer such questions as reliable bioavailability, continued safety and preservation of efficacy. In addition, an oral agent must provide patient convenience and acceptance, while being an economically sound approach. Oral vinorelbine was found to have acceptable and reliable pharmacokinetic profiles at clinically relevant dosage levels. Oral vinorelbine was found to have approximately 40…

medicine.medical_specialtyLung Neoplasmsmedicine.drug_classAdministration OralPharmacologyVinorelbineVinblastineRoute of administrationchemistry.chemical_compoundOral administrationCarcinoma Non-Small-Cell LungAntineoplastic Combined Chemotherapy ProtocolsMedicineAntiemeticHumansPharmacology (medical)Randomized Controlled Trials as Topicbusiness.industryCombination chemotherapyVinorelbineAntineoplastic Agents PhytogenicCombined Modality TherapyGemcitabineCarboplatinBioavailabilitySurgerychemistryOral vinorelbine small cell lung cancer.businessmedicine.drugDrugs
researchProduct