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Confinement effects on the interactions of native DNA with Cu(II)-5-triethyl ammonium methyl salicylidene orto-phenylendiiminate in C12E4 liquid crys…

2008

Confinement effects of native calf thymus DNA interacting with the complex Cu(ii)-5-(triethylammoniummethyl)salicylidene ortho-phenylendiiminate (CuL(2+)) perchlorate in tetraethylene glycol monododecyl ether (C(12)E(4)) liquid crystals have been investigated by UV absorption spectrophotometry, circular dichroism (CD) and small angle X-ray scattering (SAXS). The results indicate the occurrence of dramatic structural changes of both the DNA and the CuL(2+)-DNA system, when going from aqueous solution to C(12)E(4) liquid crystals, due to confinement constrains imposed by the closed structure of C(12)E(4) reverse micelles. Further marked departures from the behaviour observed in aqueous soluti…

URBAN RESILIENCE AND WASTE MANAGEMENT: PROPOSALS OF NEW INFRASTRUCTURES FOR URBAN AREAS AND BUILDINGS

2015

La produzione ingente di rifiuti, quale conseguenza di costumi di vita volti allo spreco, rende vulnerabili i sistemi urbani che possono essere sottoposti, in casi emergenziali, a pressioni eccezionali e incontrollate con situazioni prossime al collasso. Un’opportuna e corretta gestione integrata dei rifiuti contribuisce alla resilienza dei sistemi urbani. Perciò si rendono necessarie la pianificazione e la progettazione di nuovi servizi e l’individuazione/integrazione di spazi e dotazioni tecnologiche per incentivare la popolazione a effettuare la raccolta differenziata in modo corretto e costante. Si presentano gli esiti di uno studio svolto in un piccolo centro siciliano. Partendo dalle …

Role of positron emission tomography (PET) in advanced stage non-small cell lung cancer patients treated with cisplatin-based doublets

2008

Tolerance towards resident intestinal flora in mice is abrogated in experimental colitis and restored by treatment with interleukin-10 or antibodies …

1996

There is now increasing evidence that hyperresponsiveness towards intestinal flora is a crucial event in the pathogenesis of inflammatory bowel disease (IBD). In support of this hypothesis, we recently described in humans that tolerance exists towards indigenous intestinal flora but is broken in active IBD lesions. In the present study, we have attempted to transfer this model into mice from different genetic backgrounds (BALB/c, SJL/J, C3H/HeJ). We found that mononuclear cells from spleen, small bowel and large bowel of mice do not proliferate, i.e. are tolerant when exposed to bacterial sonicates derived from autologous intestine (BsA) but do proliferate, i.e. are immune when exposed to b…

2-Cinnamamido, 2-(3-phenylpropiolamido), and 2-(3-phenylpropanamido)benzamides: synthesis, antiproliferative activity, and mechanism of action

2013

Abstract Several new benzamides 4a–q were synthesized by stirring in pyridine the acid chlorides 3a–q with the appropriate anthranilamide derivatives 2a–g. Some of the synthesized compounds were evaluated for their in vitro antiproliferative activity against a panel of 5 human cell lines (K562 human chronic myelogenous leukemia cells, MCF-7 breast cancer cells, HTC-116 and HT26 colon cancer cells and NCI H460 non-small cell lung cancer cells).

Proliferation state and polo-like kinase1 dependence of tumorigenic colon cancer cells.

2012

Abstract Tumor-initiating cells are responsible for tumor maintenance and relapse in solid and hematologic cancers. Although tumor-initiating cells were initially believed to be mainly quiescent, rapidly proliferating tumorigenic cells were found in breast cancer. In colon cancer, the proliferative activity of the tumorigenic population has not been defined, although it represents an essential parameter for the development of more effective therapeutic strategies. Here, we show that tumorigenic colon cancer cells can be found in a rapidly proliferating state in vitro and in vivo, both in human tumors and mouse xenografts. Inhibitors of polo-like kinase1 (Plk1), a mitotic kinase essential fo…

Coordination games with asymmetric payoffs: An experimental study with intra-group communication

2020

Abstract Two alternative modes of reasoning in coordination games are prominently discussed in the literature: level-k thinking and team reasoning. In order to differentiate between the two modes of reasoning, we experimentally investigate payoff-asymmetric coordination games using an intra-group communication design that incentivizes subjects to explain the reasoning behind their decisions. We find that the reasoning process is significantly different between games. In payoff-symmetric games, team reasoning plays an important role for coordination. In payoff-asymmetric games, level-k reasoning results in frequent miscoordination. Our study clearly illustrates how small differences between …

Bullying at School and in the Workplace: A Challenge for Communication Research

2006

In this chapter, previous literature concerning school bullying and workplace harassment is reviewed from a communication perspective. The chapter details the seriousness and extensiveness of bullying, among both children at school and adults at work. We intend to provoke discussion of how communication research and theory might help us in understanding and explaining bullying. As elaborated here, bullying appears in interaction situations, mostly in the forms of verbal and nonverbal communication; it exists in the interpersonal relationship of bully and victim, and it can be associated with group communication processes and the structuration of groups, as well as with organizational and cu…

RUOLO DELL'ANGIO-TC NELLA DIAGNOSI DI URGENZA DI ANGIODISPLASIA INTESTINALE ILEALE: UNA RARA CAUSA DI SANGUINAMENTO

2018

Functional consequences of prey acclimation to ocean acidification for the prey and its predator

2016

Ocean acidification is the suite of chemical changes to the carbonate system of seawater as a consequence of anthropogenic carbon dioxide (CO2) emissions. Despite a growing body of evidences demonstrating the negative effects of ocean acidification on marine species, the consequences at the ecosystem level are still unclear. One factor limiting our ability to upscale from species to ecosystem is the poor mechanistic understanding of the functional consequences of the observed effects on organisms. This is particularly true in the context of species interactions. The aim of this work was to investigate the functional consequence of the exposure of a prey (the mussel Brachidontes pharaonis) t…