Search results for " System P"
showing 10 items of 181 documents
Formation and function of a complement-activating enzyme generated from factors of guinea pig serum and cobra venom
1971
An enzymatic complex can be formed by factors from guinea pig serum and cobra venom, which is able to activate C3 bypassing C1, C4 and C2. Formation and action of the enzyme are described. The action on C3 results in an activation of the terminal complement components and in membrane destruction provided suitable membrane receptors are available.
The Role of Anticipatory Emotions and their Contagiousness in an IS Project
2020
The previous research has shown increasing interest in understanding anticipatory emotions and their contagion, which can happen in dyads or groups as well as in other settings in organizations. The role of anticipatory emotions and their behavioral effects remain unexplored in IS projects. To address the research gap, we conducted a qualitative and longitudinal case study in order to understand what arethe role and consequences of the anticipatory emotions in IS project work, and how their contagiousness emerges over time. Adopting a model of group emotional contagion as a theoretical lens provided us with an opportunity to explain the relationship between anticipatory emotions and emotion…
Investigating applicability of ratings of indicators of the CLASS Pre-K instrument
2022
When classroom observations are increasingly used for accountability and evaluation purposes, a deeper understanding of the psychometric properties of such measurement tools is needed. The present study took a unique approach to examine the psychometric properties of a commonly used classroom observation measure by testing the reliability of indicators for higher-order constructs (i.e. dimensions). We investigated the reliability of indicator ratings of the Classroom Assessment Scoring System (CLASS) Pre-K instrument in Finnish kindergarten and first grade classrooms. Twenty-one observer pairs rated 838 segments identified from the 413 lessons of 48 teachers. Variance components models were…
RNA-Binding Proteins as Epigenetic Regulators of Brain Functions and Their Involvement in Neurodegeneration.
2022
A central aspect of nervous system development and function is the post-transcriptional regulation of mRNA fate, which implies time- and site-dependent translation, in response to cues originating from cell-to-cell crosstalk. Such events are fundamental for the establishment of brain cell asymmetry, as well as of long-lasting modifications of synapses (long-term potentiation: LTP), responsible for learning, memory, and higher cognitive functions. Post-transcriptional regulation is in turn dependent on RNA-binding proteins that, by recognizing and binding brief RNA sequences, base modifications, or secondary/tertiary structures, are able to control maturation, localization, stability, and tr…
Monoclonal antibodies against components of the classical pathway of complement.
1989
Activation of the classical pathway of complement involves several binding and enzymatic cleavage processes. Binding and enzymatic activation results in the appearance of new structures in the individual components. This report describes the different activation steps for C1q, C1r, C1s, C4 and C2 and summarizes monoclonal antibodies reported so far which recognize either conserved epitopes or activation-dependent epitopes with particular emphasis on neoepitopes occurring during the activation cascade.
Evaluation of a murine single-blood-injection SAH model.
2014
The molecular pathways underlying the pathogenesis after subarachnoid haemorrhage (SAH) are poorly understood and continue to be a matter of debate. A valid murine SAH injection model is not yet available but would be the prerequisite for further transgenic studies assessing the mechanisms following SAH. Using the murine single injection model, we examined the effects of SAH on regional cerebral blood flow (rCBF) in the somatosensory (S1) and cerebellar cortex, neuro-behavioural and morphological integrity and changes in quantitative electrocorticographic and electrocardiographic parameters. Micro CT imaging verified successful blood delivery into the cisterna magna. An acute impairment of …
Endocrinology and physiology of pseudocyesis
2013
This literature review on pseudocyesis or false pregnancy aims to find epidemiological, psychiatric/psychologic, gynecological and endocrine traits associated with this condition in order to propose neuroendocrine/endocrine mechanisms leading to the emergence of pseudocyetic traits. Ten women from 5 selected studies were analyzed after applying stringent criteria to discriminate between cases of true pseudocyesis (pseudocyesis vera) versus delusional, simulated or erroneous pseudocyesis. The analysis of the reviewed studies evidenced that pseudocyesis shares many endocrine traits with both polycystic ovarian syndrome and major depressive disorder, although the endocrine traits are more akin…
Mid- to Long-Term Outcomes of Cervical Disc Arthroplasty versus Anterior Cervical Discectomy and Fusion for Treatment of Symptomatic Cervical Disc Di…
2015
Purpose This study aimed to investigate the mid- to long-term outcomes of cervical disc arthroplasty (CDA) versus anterior cervical discectomy and fusion (ACDF) for the treatment of 1-level or 2-level symptomatic cervical disc disease. Methods Medline, Embase, and the Cochrane Central Register of Controlled Trials databases were searched to identify relevant randomized controlled trials that reported mid- to long-term outcomes (at least 48 months) of CDA versus ACDF. All data were analyzed by Review Manager 5.3 software. The relative risk (RR) and 95% confidence intervals (CIs) were calculated for dichotomous variables. The weighted mean difference (WMD) and 95%CIs were calculated for conti…
Transfery poselskie w Sejmie III RP jako element strategii politycznej
2019
The article aims to explain the phenomenon of parliamentary party switching in the context of political strategy Switching parties by legislators during the term is often seen as an opportunistic behavior, focused on obtaining attractive places on electoral party lists The paper’s goals are to determine if the legislators’ will to switch parties is correlated with the party public support and, finally, if the deputies truly have better chances of winning reelection if they switch parties
An Innovative Power Line Communication solution For Medium Voltage Smart Grids Applications
2018
This paper summarizes the authors research activity concerning the design, modeling and experimental characterization of a new coupling system for medium voltage (MV) narrow band power line communications (NB-PLC). The proposed solution has been patented by authors and it exploits the capacitive divider of voltage detecting systems (VDSs) normally used to reveal the mains voltage presence, thus avoiding the use of dedicated MV couplers. In the following, the modeling of the VDS capacitive divider is presented and the interface card design is described, based on simulation of the whole PLC transmission channel. Laboratory tests are also presented. Finally, the results are shown of an on-fiel…