Search results for " Technology"
showing 10 items of 23337 documents
Trans -Cyclooctene-Functionalized PeptoBrushes with Improved Reaction Kinetics of the Tetrazine Ligation for Pretargeted Nuclear Imaging
2020
Tumor targeting using agents with slow pharmacokinetics represents a major challenge in nuclear imaging and targeted radionuclide therapy as they most often result in low imaging contrast and high radiation dose to healthy tissue. To address this challenge, we developed a polymer-based targeting agent that can be used for pretargeted imaging and thus separates tumor accumulation from the imaging step in time. The developed targeting agent is based on polypeptide-graft-polypeptoid polymers (PeptoBrushes) functionalized with trans-cyclooctene (TCO). The complementary In-111-labeled imaging agent is a 1,2,4,5-tetrazine derivative, which can react with aforementioned TCO-modified PeptoBrushes i…
Effect of Hot Dip Galvanized Steel Surface Chemistry and Morphology on Titanium Hexafluoride Pretreatment
2017
Titanium hexafluoride pretreatments are known to improve paint adhesion and function as a barrier between the coating and the hot dip galvanized (HDG) steel surface. Interactions at the zinc/pretreatment interface are of utmost importance for the formation of pretreatment layers and the corrosion resistance of color coated hot dip galvanized steels. Removal rate of inert aluminum oxide from HDG steel samples by chemical dissolution was studied. XPS measurements showed that the surface Al2O3 layer thickness decreased rapidly already at mild alkaline cleaning, while complete removal of Al required severe etching. Low reactivity of an Al2O3-rich surface was confirmed by impaired formation of a…
La valeur économique des paysages des villes périurbanisées
2007
La recherche présentée ici propose une méthode de description et d’évaluation des caractéristiques d’un paysage qui combine la géographie quantitative et l’économétrie des modèles hédoniques. Un modèle géographique produit des indices caractérisant les paysages à partir d’une reconstitution de la vue depuis le sol, en tenant compte des effets du relief et des masques que les objets hauts opposent à la vue. Il décrit la quantité de paysage vu par un observateur au niveau du sol en la répartissant entre 13 types d’occupations du sol. Les variables produites par le modèle géographique sont utilisées dans des régressions hédoniques qui permettent d’évaluer l’impact des attributs paysagers ain…
Probing a Proactive Home : Challenges in Researching and Designing Everyday Smart Environments
2006
Based on the results of a 3-year interdisciplinary study, this article presents an approach in which proactive information technology was introduced into homes, and discusses the derived design principles from a human-centered perspective. The application of proactive computing in homes will face particularly sensitive conditions, as familiar and reliable household elements remain strongly preferred. Since there is considerable resistance towards the increase of information technology in homes, both the calm system behaviors and the degree of variety in aesthetic designs will play major roles in the acceptance of proactive technology. If proactive technology will be an embedded part of a ho…
Probabilistic Evaluation of the Adaptation Time for Structures under Seismic Loads
2016
Abstract In this paper, a probabilistic approach for the evaluation of the adaptation time for elastic perfectly plastic frames is proposed. The considered load history acting on the structure is defined as a suitable combination of quasi-statical loads and seismic actions. The proposed approach utilizes the Monte Carlo method in order to generate a suitable large number of seismic acceleration histories and for each one the related load combination is defined. Furthermore, for each load combination the related adaptation time is determined, if any, as the optimal one for which the structure is able to shakedown under the unamplified applied actions. A known generalized Ceradini's theorem i…
Wykorzystanie technologii informacyjnej w kształceniu na przykładzie programu GeoGebra
2016
W artykule poruszona została kwestia wykorzystania technologii informacyjnej w procesie kształcenia. Dzisiejsza szkoła musi korzystać z odpowiedniego oprogramowania dydaktycznego, które powoduje, że uczeń chętniej przyswaja wiadomości, a rezultatem tego jest bardziej efektywne kształcenie. Jednym z takich programów jest GeoGebra, która usprawnia nauczanie matematyki.Jest to uniwersalna aplikacja, która doskonale nadaje się do wykorzystania na wszystkich etapach kształcenia.
How different policy instruments affect green product innovation : A differentiated perspective
2018
Based on representative firm-level data for the three countries Austria, Germany, and Switzerland, we investigate the effects of energy-related regulations, taxes, voluntary agreements, and subsidies on the creation of green energy products, and analyze through which channels policy affects green product innovation and which factors mediate the observed effects. Policy may affect green product innovation by directly stimulating the supply of green products/services, or more indirectly by stimulating the demand for green products/services. Our data set allows us to distinguish between the two channels, which improves our understanding of the frequently observed positive net effect of policie…
Challenges Associated with Byproducts Valorization—Comparison Study of Safety Parameters of Ultrasonicated and Fermented Plant-Based Byproducts
2020
In order to promote the efficient use of byproducts from the production of plant-based beverages, which still contain a large amount of nutritional and functional compounds, microbiological and chemical safety characteristics should be evaluated and, if needed, improved. Many challenges are associated with byproducts valorization, and the most important ones, which should be taken into account at the further steps of valorization, are biological and chemical safety. For safety improving, several technological treatments (biological, physical etc.) can be used. In this study, the influence of low-frequency ultrasonication (US) and fermentation with Lactobacillus casei LUHS210 strain, as phys…
Crowdfunding performance, market performance, and the moderating roles of product innovativeness and experts' judgment: Evidence from the movie indus…
2023
Reward-based crowdfunding (CF) has emerged as a method to solicit funds for innovative projects. Yet, little is still known about the ability of reward-based CF to act as a signal in the eyes of future consumers, and thus boost the future market performance of new products that innovators intend to commercialize using the campaign funds. In addition, scant research has clarified the boundary conditions that can magnify or weaken the efficacy of this CF signal. Given the relevance of reward-based CF for supporting innovation, understanding when the CF campaign performance works as an effective signal is of great interest, especially in business settings characterized by high product quality …
Product market regulation, innovation and productivity
2014
Several recent policy and academic contributions consider that liberalising product markets would foster innovation and growth. This paper analyses the innovation-productivity relationship at the industry-level for a sample of OECD manufacturing industries. We pay particular attention to the vertically-induced influence of product market regulation (PMR) of key input sectors of the economy on the innovative process of manufacturing and its consequences on productivity. We test for a differentiated effect of this type of PMR depending on whether countries are technological leaders or laggards in a given industry and for a given time period. Contrary to the most widespread policy claims, the …