Search results for " Trait"
showing 10 items of 764 documents
Hereditary gingival fibromatosis: clinical and ultrastructural features of a new family
2014
Objective: This article describes the diagnosis, clinical and microscopic (histopathology and ultrastructural) features and treatment of a new family with hereditary gingival fibromatosis (HGF) and highlights the importance of this genetic condition. Study Design: To characterize the pattern of inheritance and the clinical features, members of a new family with HGF were examined. The pedigree was reliably constructed including the four latest generations of family. Hematoxylin and eosin staining and ultrastructural analysis were performed with the gingival tissue. Results: Examination of the family pedigree revealed that the patient III-2 represent the index patient of this family (initial …
New susceptibility locus for coronary artery disease on chromosome 3q22.3
2009
We present a three-stage analysis of genome-wide SNP data in 1,222 German individuals with myocardial infarction and 1,298 controls, in silico replication in three additional genome-wide datasets of coronary artery disease (CAD) and subsequent replication in approximately 25,000 subjects. We identified one new CAD risk locus on 3q22.3 in MRAS (P = 7.44 x 10(-13); OR = 1.15, 95% CI = 1.11-1.19), and suggestive association with a locus on 12q24.31 near HNF1A-C12orf43 (P = 4.81 x 10(-7); OR = 1.08, 95% CI = 1.05-1.11).
Advances in Alcoholism Research in Germany
2005
This article presents the proceedings of a symposium at the 2004 International Society for Biomedical Research on Alcoholism meeting in Heidelberg/Mannheim, Germany, put together by the German Society of Addiction Therapy and Research (DG-Sucht e.V.). The aim was to give an overview on recent findings from animal to human studies that were conducted by several research groups engaged in the alcoholism field in Germany for longer periods. Results of his animal studies were presented by J. Wolfgramm; G. Buchringer reported on epidemiologic and psychotherapeutic research advances on alcohol-related disorders in Germany. L. G. Schmidt summarized results of novel diagnostic and therapeutic appro…
Relationship of subjective helplessness and pain perception after electric skin stimuli
2000
Objective and subjective controllability of painful stimuli are important factors in pain perception. The present study investigated direct and indirect effects of uncontrollability on perceived pain intensity in humans. Forty-eight healthy male volunteers participated in a laboratory experiment using a reaction time paradigm to induce controllable or uncontrollable feedback conditions in two randomly selected groups. Under controllable conditions, unpleasant electric skin shocks were applied, only when the actual time exceeded an individual threshold; under uncontrollable conditions, skin shocks were applied randomly using a yoked control design. Subjective helplessness, perceived pain int…
Cell-Free Fetal DNA and Non-Invasive Prenatal Diagnosis of Chromosomopathies and Pediatric Monogenic Diseases: A Critical Appraisal and Medicolegal R…
2022
Cell-free fetal DNA (cffDNA) analysis is a non-invasive prenatal diagnostic test with a fundamental role for the screening of chromosomic or monogenic pathologies of the fetus. Its administration is performed by fetal DNA detection in the mother’s blood from the fourth week of gestation. Given the great interest regarding its validation as a diagnostic tool, the authors have set out to undertake a critical appraisal based on a wide-ranging narrative review of 45 total studies centered around such techniques. Both chromosomopathies and monogenic diseases were taken into account and systematically discussed and elucidated. Not surprisingly, cell-free fetal DNA analysis for screening purposes …
Sex-specific effects of natural and sexual selection on the evolution of life span and ageing in Drosophila simulans
2014
Summary Variation in the strength of age-dependent natural selection shapes differences in ageing rates across species and populations. Likewise, sexual selection can promote divergent patterns of senescence across the sexes. However, the effects of these processes on the evolution of ageing have largely been considered independently, and interactions between them are poorly understood. We use experimental evolution to investigate how natural and sexual selection affect life span and ageing in Drosophila simulans. Replicate populations were evolved under lifetime monogamy (relaxed sexual selection) or lifetime polyandry (elevated sexual selection) and at one of two temperatures, 25 °C (rela…
Effects of Personal Traits on Generation Y Consumers' Attitudes Toward the Use of Mobile Devices for Communication and Commerce
2012
The purpose of this study was to investigate the effects of young adult consumers’ personal traits (high-tech involvement, experiment proclivity, and fashion/brand leadership) on their perceptions of and attitudes toward using mobile devices for communications and commerce. The integrated stimulus-organism-responses paradigm (Fiore & Kim, 2007) served as the overarching framework, combining the uses and gratifications theory (Blumler & Katz, 1974) and the extended technology acceptance model (Kim, Ma, & Park, 2009). A convenience sample of 504 college students in 2 U. S. universities provided usable responses to our survey. Causal modeling analysis results showed that personal trait varia…
Who enjoys listening to sad music and why?
2011
although people generally avoid negative emotional experiences in general, they often enjoy sadness portrayed in music and other arts. The present study investigated what kinds of subjective emotional experiences are induced in listeners by sad music, and whether the tendency to enjoy sad music is associated with particular personality traits. One hundred forty-eight participants listened to 16 music excerpts and rated their emotional responses. As expected, sadness was the most salient emotion experienced in response to sad excerpts. However, other more positive and complex emotions such as nostalgia, peacefulness, and wonder were also evident. Furthermore, two personality traits – Opennes…
Data from: The interplay of nested biotic interactions and the abiotic environment regulates populations of a hypersymbiont
2019
1. The role of biotic interactions in shaping distribution and abundance of species should be particularly pronounced in symbionts. Indeed, symbionts have a dual niche composed of traits of their individual hosts and the abiotic environment external to the host, and often combine active dispersal at finer scales with host-mediated dispersal at broader scales. The biotic complexity in the determinants of species distribution and abundance should be even more pronounced for hypersymbionts (symbionts of other symbionts). 2. We use a chain of symbiosis to explore the relative influence of nested biotic interactions and the abiotic environment on occupancy and abundance of a hypersymbiont. 3. Ou…
Analyse de la crise économique actuelle au regard du droit des investissements internationaux
2009
National audience