Search results for " Vaccination"

Vaccination in old age: Challenges and promises

2021

Abstract Vaccination is one of the most effective medical interventions ever introduced, preventing millions of cases of infections worldwide every year. However, vaccines are commonly believed to be less effective in providing protection in older adults, due to the perceived decline seen in immunity in this population (“immunosenescence”). Accordingly, this chapter considers how to identify hallmarks of immunosenescence and approach their resolution strategically. It was reviewed potential options for therapeutic intervention to restore appropriate responses to vaccines in older adults.

Efficiency of Biolistic DNA Vaccination in Experimental Type I Allergy

2012

Gene gun-mediated delivery of allergen-encoding plasmid DNA has been in focus for many years now as being a needle-free alternative to the protein-based desensitization regimen used in specific immunotherapy. Biolistic immunization with the Helios gene gun has proven to be potent in the induction of antigen-specific CD4(+) and CD8(+) T cells. Here we describe biolistic vaccination in experimental mouse models of IgE-mediated type I allergy as well as allergen-induced airway inflammation.

How should vaccination services be planned, organized, and managed? Results from a survey on the Italian vaccination services

2019

Background. Quality improvement is an increasingly recognized approach to maximize service effectiveness and minimize costs in public health. However, the Italian law never provided for the institutional accreditation of vaccination services. Furthermore, a recently approved law added six more compulsory vaccinations to the original four, which has led to a considerable increase in vaccination efforts, without any previous resources evaluation. The aim of the study was to investigate structural, organizational and managerial characteristics of the Italian vaccination services, in order to suggest the adoption of adequate quality standards. Study design. A survey involving the representative…

Mapping routine measles vaccination in low- and middle-income countries

2021

The safe, highly effective measles vaccine has been recommended globally since 1974, yet in 2017 there were more than 17 million cases of measles and 83,400 deaths in children under 5 years old, and more than 99% of both occurred in low- and middle-income countries (LMICs)1–4. Globally comparable, annual, local estimates of routine first-dose measles-containing vaccine (MCV1) coverage are critical for understanding geographically precise immunity patterns, progress towards the targets of the Global Vaccine Action Plan (GVAP), and high-risk areas amid disruptions to vaccination programmes caused by coronavirus disease 2019 (COVID-19)5–8. Here we generated annual estimates of routine childhoo…

Students’ social networks and vaccination behaviour in Italian junior high schools: preliminary results from the "VacciniAmo le Scuole" project.

2015

Students; social networks; vaccination; behavior; high schools

Hepatitis B- a Therapeutic Vaccine: Hope or Hype?

2010

Cost analysis of the first two year of universal mass vaccination against rotavirus in Sicily

2015

Background Rotavirus vaccination (RV) is recognized by international health authority as the best strategy to prevent rotavirus gastroenteritis (RVGE) in children. Costs of RVGE were estimated in several studies and were classified into direct and indirect costs, that should be further divided into Health care and social perspective. This study aims to evaluate RVGE hospitalization costs in Sicily, before and after universal mass RV (UMRV) introduction. Methods Cases of RVGE were defined as all hospitalizations with an ICD-9-CM diagnosis code of 008.61 on any diagnosis position among children aged 0 to 59 months. Data were obtained from Hospital discharge records (HDR) of the Health Regiona…

T-Cell Vaccination in Patients with Nickel Allergic Contact Dermatitis

1995

Moralna odpowiedzialność rodziców za szczepienie dzieci - czynniki modyfikujące w realiach polskich

2020

Kontekst badań: Szczepienia ochronne dzieci są dobrodziejstwem dla zdrowia indywidualnych osób i epidemicznej ochrony społeczeństwa. Obserwowane narastające lawinowo zjawisko uchylania się przez rodziców od szczepień dzieci wymaga pogłębionych badań pod kątem ich odpowiedzialności moralnej za zaniechanie działania. Cel badań: zweryfikowanie hipotezy badawcze, która brzmiała: Odpowiednio silny wpływ czynnika modyfikującego postawy rodziców wobec szczepień ochronnych dzieci może zmniejszyć odpowiedzialność moralną rodziców za niepodjęcie obowiązku szczepiennego. Metoda badawcza: w badaniach zastosowano desk research, a więc analizę danych zastanych, z uwzględnieniem dostępnych dokumentów, bad…

Adaptation and Preliminary Validation of the Fear of Coronavirus Vaccination Scale in the Prospective Study among a Representative Sample of Polish, …

2022

Although concerns about harm and side effects are among the most important factors determining vaccine hesitancy, research on the fear of vaccination is sparse. The purpose of this study is a validation the Fear of Coronavirus Vaccination Scale (FoCVVS), adapted from the Fear of COVID-19 Scale. A representative sample of 1723 young adults aged 20–40 from Poland, Israel, Slovenia, and Germany participated during two time-points of the third COVID-19 pandemic wave. The online survey included demographic variables and several well-being dimensions, including gender, vaccination status, fear of coronavirus (FoCV-19S), physical health (GSRH), life satisfaction (SWLS), and perceived stress (PSS-1…