Search results for " ambientali"
showing 10 items of 774 documents
Thioflavin T Promotes Aβ(1−40) Amyloid Fibrils Formation
2015
Fibrillogenesis of the small peptide Aβ(1-40) is considered to be the hallmark of Alzheimer's disease. Some evidence indicates small oligomers, rather than mature fibrils, as the key cytotoxic agents. The fluorescent dye Thioflavin T (ThT) is often used to detect amyloid deposits in both in vivo and in vitro experiments, and it is used to study kinetic measurements, under the fundamental hypothesis that this probe does not influence the aggregation processes. We report experimental data showing that ThT may promote the Aβ(1-40) peptide amyloid aggregation changing solvent-peptide interactions and stabilizing more ordered β-like conformation. This finding has a two-fold importance: It is a f…
Translocation dynamics of a short polymer driven by an oscillating force
2013
Under the terms of the Creative Commons Attribution 3.0 Unported License.
MbCO embedded in trehalosyldextrin matrices: thermal effects and protein-matrix coupling
2010
Saccharide-based biopreservation is widely studied because of its scientific importance and possible technological outcomes for food and pharmaceutical industries. Ternary protein/saccharide/water systems have been extensively exploited to model the characteristics of the in vivo biopreservation process. A tight, water dependent, protein–matrix coupling has been shown to occur in various simple saccharide amorphous matrices, which is stronger in trehalose. The efficiency as bioprotectant of trehalose has been ascribed to this tight coupling, since the appearance of damages on biological structures will more involve structural variations of the surrounding matrix. Here we present, as an appl…
Pre-aggregates characterization and viscoelastic studies of BSA cold gels induced by metal ions
2008
L'impatto ambientale delle attività estrattive e la funzione delle misure di compensazione
2017
Il T.A.R. Toscana si pronuncia sull’impugnazione di uno stralcio di un piano provinciale delle attività estrattive per carenza e inadeguatezza della valutazione ambientale strategica, nonché sul ricorso contro un successivo provvedimento di esclusione di assoggettabilità a valutazione di impatto ambientale di un progetto di apertura di una cava. Il giudice ritiene sussistente la legittimazione ad agire dei ricorrenti, tra cui vi sono i titolari di complessi di agriturismo siti nelle vicinanze della cava, che lamentano un possibile svantaggio competitivo ed economico derivante dalla coltivazione della medesima. Il tribunale, poi, riscontra che la valutazione strategica è troppo generica e as…
A primer on statistically validated networks
2019
In this contribution we discuss some approaches of network analysis providing information about single links or single nodes with respect to a null hypothesis taking into account the heterogeneity of the system empirically observed. With this approach, a selection of nodes and links is feasible when the null hypothesis is statistically rejected. We focus our discussion on approaches using i) the so-called disparity filter and ii) statistically validated network in bipartite networks. For both methods we discuss the importance of using multiple hypothesis test correction. Specific applications of statistically validated networks are discussed. We also discuss how statistically validated netw…
Hierarchical structures in Complex Systems: from DNA to financial markets
2000
In this paper we discuss the concepts of short-range and long-range correlated stochastic processes and we investigate the presence of such variables in two model complex systems. The selected model systems are DNA sequences of complete genomes and financial time series of equities traded in a stock market. Specifically, by starting from our research results, we discuss the statistical properties of (i) coding and non-coding regions of DNA and (ii) equity returns and volatility in financial markets. The stylized facts about these variables are presented and discussed with a focus on the statistical tools already used and/or still needed to better characterize these model complex systems.
Risposte agli stress ambientali in CYSTOSEIRA (C. AGARDH): effetti della temperatura sul contenuto dei composti fenolici
2012
Phenolic compounds are secondary metabolites involved in different protection mechanisms as, for example, against grazers, epiphytes and UV radiation. Seasonal variations of phenolic content in C. amentacea were analysed and laboratory experiments, in which C. amentacea was exposed to an increase of temperature (258C and 308C), were performed. Total phenolic content (TPC) was determined colorimetrically with the Folin–Ciocalteu reagent. In C. amentacea, a seasonal pattern in TPC was observed, with a maximum value in winter-spring. C. amentacea responded significantly to the temperature treatments with a consistent decrease in TPC after 48 h.
Progress in the Development of CdTe and CdZnTe Semiconductor Radiation Detectors for Astrophysical and Medical Applications
2009
Over the last decade, cadmium telluride (CdTe) and cadmium zinc telluride (CdZnTe) wide band gap semiconductors have attracted increasing interest as X-ray and gamma ray detectors. Among the traditional high performance spectrometers based on silicon (Si) and germanium (Ge), CdTe and CdZnTe detectors show high detection efficiency and good room temperature performance and are well suited for the development of compact and reliable detection systems. In this paper, we review the current status of research in the development of CdTe and CdZnTe detectors by a comprehensive survey on the material properties, the device characteristics, the different techniques for improving the overall detector…