Search results for " array"
showing 10 items of 895 documents
On the optimal design of multi-stage cascaded transistor amplifiers with noise, gain and mismatch constraints
2007
The problem of evaluating the optimal performances of cascaded, unbalanced, multi-stage transistor amplifiers is addressed. In particular, a theoretically rigorous approach is proposed for the determination of a family of Optimal Design Curves (ODC's) which express the best noise-gain tradeoff that can be achieved - at each frequency and device operating condition - when a simultaneous constraint on amplifier input VSWR is accounted for. Such curves can be used as a more meaningful starting point in practical amplifier design in place of the approximate calculations so far employed for target performance or optimization goals determination.
On the Theoretical Limits of Noise-Gain-Mismatch Tradeoff in the Design of Multi-Stage Cascaded Transistor Amplifiers
2007
The problem of evaluating the limit performances of cascaded single-ended multi-stage transistor amplifiers is addressed. In particular, a theoretically rigorous approach is proposed for the determination of a family of optimal design curves (ODC's) which express the best (maximum optimal) noise-gain tradeoff that can be achieved - at each operating frequency - when a simultaneous constraint on amplifier input VSWR is accounted for.
Fluorescence explorer (FLEX): An optimised payload to map vegetation photosynthesis from space
2006
The FLuorescence EXplorer (FLEX) mission proposes to launch a satellite for the global monitoring of steady-state chlorophyll fluorescence in terrestrial vegetation. Fluorescence is a sensitive probe of photosynthetic function in both healthy and physiologically perturbed vegetation, and a powerful non-invasive tool to track the status, resilience, and recovery of photochemical processes and moreover provides important information on overall photosynthetic performance with implications for related carbon sequestration. The early responsiveness of fluorescence to atmospheric, soil and plant water balance, as well as to atmospheric chemistry and human intervention in land usage makes it an ob…
Direct measurement of the melting temperature of supported DNA by electrochemical method
2003
The development of biosensors based on DNA hybridization requires a more precise knowledge of the thermodynamics of the hybridization at a solid interface. In particular, the selectivity of hybridization can be affected by a lot of parameters such as the single-strand (ss)DNA density, the pH, the ionic strength or the temperature. The melting temperature, T(m), is in part a function of the ionic strength and of the temperature and therefore provides a useful variable in the control of the selectivity and sensitivity of a DNA chip. The electrochemical technique has been used to determine the T(m) values when the probe is tethered by a DNA self-assembled monolayer (SAM). We have built a speci…
Nonsense-mediated mRNA decay controls the changes in yeast ribosomal protein pre-mRNAs levels upon osmotic stress.
2013
The expression of ribosomal protein (RP) genes requires a substantial part of cellular transcription, processing and translation resources. Thus, the RP expression must be tightly regulated in response to conditions that compromise cell survival. In Saccharomyces cerevisiae cells, regulation of the RP gene expression at the transcriptional, mature mRNA stability and translational levels during the response to osmotic stress has been reported. Reprogramming global protein synthesis upon osmotic shock includes the movement of ribosomes from RP transcripts to stress-induced mRNAs. Using tiling arrays, we show that osmotic stress yields a drop in the levels of RP pre-mRNAs in S. cerevisiae cell…
A first comparative map of copy number variations in the sheep genome.
2011
article i nfo We carried out a cross species cattle-sheep array comparative genome hybridization experiment to identify copy number variations (CNVs) in the sheep genome analysing ewes of Italian dairy or dual-purpose breeds (Bagnolese, Comisana, Laticauda, Massese, Sarda, and Valle del Belice) using a tiling oligonucleotide array with ~385,000 probes designed on the bovine genome. We identified 135 CNV regions (CNVRs; 24 reported in more than one animal) covering ~10.5 Mb of the virtual sheep genome referred to the bovine genome (0.398%) with a mean and a median equal to 77.6 and 55.9 kb, respectively. A comparative analysis between the identified sheep CNVRs and those reported in cattle a…
Oxidative C-N fusion of pyridinyl-substituted porphyrins.
2018
International audience; The mild (electro) chemical oxidation of pyridin-2-ylthio-meso substituted Ni(II) porphyrins affords C-N fused cationic and dicationic pyridinium-based derivatives. These porphyrins are fully characterized and the molecular structure of one of them was confirmed by X-ray crystallography. A mechanism for the intramolecular oxidative C-N coupling is proposed based on theoretical calculations and cyclic voltammetry analyses.
Spectral and morphological analysis of the remnant of Supernova 1987A with ALMA and ATCA
2014
We present a comprehensive spectral and morphological analysis of the remnant of Supernova (SN) 1987A with the Australia Telescope Compact Array (ATCA) and the Atacama Large Millimeter/submillimeter Array (ALMA). The non-thermal and thermal components of the radio emission are investigated in images from 94 to 672 GHz ($\lambda$ 3.2 mm to 450 $\mu$m), with the assistance of a high-resolution 44 GHz synchrotron template from the ATCA, and a dust template from ALMA observations at 672 GHz. An analysis of the emission distribution over the equatorial ring in images from 44 to 345 GHz highlights a gradual decrease of the east-to-west asymmetry ratio with frequency. We attribute this to the shor…
Technical and economical comparison between different topologies of PV plant under mismatch effect
2014
This paper presents a technical and economical comparative analysis between two topology of photovoltaic plant. In particular the performances of series-parallel (SP) and total cross tied (TCT), topologies are taken into account, referring to a partially shaded photovoltaic plant. Thanks to a simulation model developed, in the paper the mismatch effects due to three different shading conditions, for SP and TCT topology plant, are quantified. Since the TCT solution, even though increase the energy production, raise the complexity of plants as well as their costs, an evaluation of the individual costs of each component of a SP and TCT plant topology, as PV modules, support structure, inverter…
Transcript profiling identifies novel key players mediating the growth inhibitory effect of NS-398 on human pancreatic cancer cells
2010
Pancreatic cancer is one of the most aggressive human malignancies with an increasing incidence worldwide. Despite an increase in the number of systemic treatments available for pancreatic cancer, the impact of therapy on the clinical course of the disease has been modest, underscoring an urgent need for new therapeutic options. Although selective cyclooxygenase-2 inhibitors have been demonstrated to have cancer-preventive effects, the mechanism of their effects is not clearly known. Moreover, there have been no unbiased studies to identify novel molecular targets of NS-398 regarding pancreatic cancer. Here we undertook a gene expression profiling study to identify novel molecular targets m…