Search results for " case"
showing 10 items of 871 documents
Internal Software Startups - A Multiple Case Study on Practices, Methods, and Success Factors
2020
Startups are often seen as drivers of innovation. In an attempt to leverage this potential, larger business organizations have founded internal startups as a subset of internal corporate ventures (ICV). These smaller organizations are intended to be more agile than the parent organization, in order to produce new service and product innovations using their own methods and practices independently of the organizational culture and methods of the parent organization. However, our understanding of ICVs is still lacking in terms of processes and success factors, and especially the more recent internal startups have scarcely been studied thus far. To approach this novel area of research, we take …
Identifying reasons for ERP system customization in SMEs: a multiple case study
2012
PurposeThe purpose of this paper is to investigate possible reasons for enterprise resource planning (ERP) system customization in small and medium‐sized enterprises (SMEs), with a particular focus on distinguishing influential factors of the SME context.Design/methodology/approachAn exploratory qualitative research approach was employed, to identify new insights within the SME context. A multiple case study of four SMEs was conducted. Data were collected through 34 qualitative interviews with multiple informants across the four cases.FindingsThe paper reports findings from four SMEs where ERP customization has been applied to match organizational needs. First, the level and type of ERP sys…
Extending the international new venture phenomenon to digital platform providers : A longitudinal case study
2018
People increasingly interact with services enabled by digital platforms. This has been a consequence of the digitalization of artifacts, which has transmuted traditional businesses into digital forms. With the increasing digitalization and modularization of services, digital platforms have given many digital service providers possibilities to scale globally, and to rapidly transcend national borders by serving multi-sided markets. However, we still know very little about how digital platform providers actually internationalize their services, or how they make their platforms available for global markets. In this paper, we contribute to the increasing literature on digital-based INVs, examin…
Educare il bambino alla vita interiore. La lezione di Maria Montessori nel tempo della post-democrazia
2014
Maria Montessori’s pedagogy of interiority carried out in the “Houses of Children” is relevant to the postmodern age. By focusing on the care of the child’s inner life, Montessori’s lesson offers the new generations authentic religious practices, thus responding to the new, increasingly widespread, need for sacred. On this wake, contemporary pedagogy is re-launching childhood as a new resource for the adult, endeavouring to transform the environments where education takes place into laboratories of peace and democracy.
Reduction in vitro of the minor Fusarium mycotoxin beauvericin employing different strains of probiotic bacteria
2012
Abstract The interaction between the minor Fusarium mycotoxins BEA and 13 bacterial strains characteristic of the gastrointestinal tract as Bifidobacterium longum , Bifidobacterium bifidum , Bifidobacterium breve , Bifidobacterium adolescentes , Lactobacillus rhamnosus , Lactobacillus casei-casei , Lactobacillus plantarum , Eubacterium crispatus , Salmonella fecalis , Salmonella termofilus , Lactobacillus ruminis , Lactobacillus casei and Lactobacillus animalis was studied. The fermentations were carried out in the liquid medium of MRS during 4, 12, 16, 24 and 48 h at 37 °C, under anaerobic conditions. Levels of BEA in the fermentation liquid, on the cell walls and on the internal part of t…
Caseicin 80: purification and characterization of a new bacteriocin from Lactobacillus casei
1990
When grown in complex or synthetic media, Lactobacillus casei B 80 synthesizes a mitomycin C-inducible polypeptide with very specific bactericidal activity against the sensitive strain Lactobacillus casei B 109. The amount of secreted bacteriocin in the culture solution was low, about 1 mg/l. The bacteriocin which we called caseicin 80, was also detectable in cell extracts, although only 2% of the total activity was retained intracellularly. Caseicin 80 was concentrated by ultrafiltration and purified by cation exchange chromatography with Cellulose SE-23 and Superose. The molecular weight was in the range of M r=40,000–42,000 and the isoelectric point was pH 4.5.
Study and optimization of freeze-drying cycles of a model probiotic strain
2018
This work is based on the experimental study of the freeze-drying process to understand the impact of numerous factors on the survival rates of a model probiotic strain of Lactobacillus casei type. With the aim to find out if cell density in the matrix and survival rates are linked, we have studied the location of the cells after freeze drying inside a porous matrix composed of a lactose basis with a polymer, the polyvinylpyrrolidone (PVP) in various amounts. The best survival rate were obtained at slow freezing rate for a formulation containing 5% (m/V) of lactose and 5% (m/V) of PVP. Keywords: Freeze-Drying; Freezing; Probiotics; L. Casei ATCC 393
Das Vorkommen von Malatenzym und Malo-Lactat-Enzym bei verschiedenen Milchs�urebakterien
1974
1. Bei drei Stammen vonLactobacillus casei, die auf Apfelsaure als C-Quelle wuchsen, wurde durch Kultur mit Apfelsaure entweder Malatenzym oder durch Kultur mit Apfelsaure und Glucose Malo-Lactat-Enzym induziert. Zwei Stamme vonStreptococcus faecalis bildeten nur Malatenzym,Streptococcus lactis, der Glucose zum Wachstum braucht, nur Malo-Lactat-Enzym. 2. Durch aufeinanderfolgende Induktion wurden Zellen vonLactobacillus casei M40 mit Malatenzym und Malo-Lactat-Enzym erhalten. 3. Malatenzym und Malo-Lactat-Enzym unterscheiden sich im Induktionsverhalten, im pH-Optimum, in der Affinitat zum Substrat, in den Endprodukten und im Molekulargewicht.
Unique Microbial Catabolic Pathway for the Human Core N-Glycan Constituent Fucosyl-α-1,6-N-Acetylglucosamine-Asparagine
2020
The survival of commensal bacteria in the human gut partially depends on their ability to metabolize host-derived molecules. The use of the glycosidic moiety of N-glycoproteins by bacteria has been reported, but the role of N-glycopeptides or glycoamino acids as the substrates for bacterial growth has not been evaluated. We have identified in Lactobacillus casei strain BL23 a gene cluster (alf-2) involved in the catabolism of the glycoamino acid fucosyl-α-1,6-N-GlcNAc-Asn (6′FN-Asn), a constituent of the core-fucosylated structures of mammalian N-glycoproteins. The cluster consists of the genes alfHC, encoding a major facilitator superfamily (MFS) permease and the α-l-fucosidase AlfC, and t…
Malic Enzyme and Malolactic Enzyme Pathways Are Functionally Linked but Independently Regulated in Lactobacillus casei BL23
2013
ABSTRACT Lactobacillus casei is the only lactic acid bacterium in which two pathways for l -malate degradation have been described: the malolactic enzyme (MLE) and the malic enzyme (ME) pathways. Whereas the ME pathway enables L. casei to grow on l -malate, MLE does not support growth. The mle gene cluster consists of three genes encoding MLE ( mleS ), the putative l -malate transporter MleT, and the putative regulator MleR. The mae gene cluster consists of four genes encoding ME ( maeE ), the putative transporter MaeP, and the two-component system MaeKR. Since both pathways compete for the same substrate, we sought to determine whether they are coordinately regulated and their role in l -m…