Search results for " culture"
showing 10 items of 5779 documents
Weed-DATA Base de données ‘Traits’ des plantes adventices des agroécosystèmes
2014
SPEEAECOLDURGEAPSIéquipe CAPA; absent
Extracellular Vesicle microRNAs Contribute to the Osteogenic Inhibition of Mesenchymal Stem Cells in Multiple Myeloma
2020
Osteolytic bone disease is the major complication associated with the progression of multiple myeloma (MM). Recently, extracellular vesicles (EVs) have emerged as mediators of MM-associated bone disease by inhibiting the osteogenic differentiation of human mesenchymal stem cells (hMSCs). Here, we investigated a correlation between the EV-mediated osteogenic inhibition and MM vesicle content, focusing on miRNAs. By the use of a MicroRNA Card, we identified a pool of miRNAs, highly expressed in EVs, from MM cell line (MM1.S EVs), expression of which was confirmed in EVs from bone marrow (BM) plasma of patients affected by smoldering myeloma (SMM) and MM. Notably,we found that miR-129-5p, whic…
Literarische Übersetzung zwischen Autotranslation und Neuschöpfung: Brygida Helbigs "Niebko" versus "Kleine Himmel"
2023
Artykuł poświęcony jest analizie translatorycznej powieści Brygidy Helbig pt. Niebko (2013) oraz jej niemieckiego przekładu (Kleine Himmel, 2019). Porównanie obu wersji pozwala stwierdzić liczne rozbieżności. Przyjęta perspektywa translatologiczna ma charakter interdyscyplinarny, łączy elementy językoznawcze oraz literaturoznawcze. Wnioski z analizy stanowią przyczynek do refleksji na temat przekładu literatury interkulturowej, zjawiska autotranslacji oraz redefinicji pojęcia „przekład”.
The prolyl-isomerase PIN1 is essential for nuclear Lamin-B structure and function and protects heterochromatin under mechanical stress.
2021
Summary: Chromatin organization plays a crucial role in tissue homeostasis. Heterochromatin relaxation and consequent unscheduled mobilization of transposable elements (TEs) are emerging as key contributors of aging and aging-related pathologies, including Alzheimer’s disease (AD) and cancer. However, the mechanisms governing heterochromatin maintenance or its relaxation in pathological conditions remain poorly understood. Here we show that PIN1, the only phosphorylation-specific cis/trans prolyl isomerase, whose loss is associated with premature aging and AD, is essential to preserve heterochromatin. We demonstrate that this PIN1 function is conserved from Drosophila to humans and prevents…
Nowa szkolna polonistyka czy powrót do źródeł? Rozważania o kształceniu literackim we współczesnej szkole
2018
Pytanie o „starą" i „nową" polonistykę szkolną jest wciąż aktualne. Pojawia się w wielu dyskusjach na temat polonistycznego kształcenia. Namysł nad nim prowadzi do kilku spostrzeżeń: uczenie literatury, uczenie odbioru tekstu zasadza się na wartościach stałych i niezbywalnych; jest procesem; stwarza czytelnika, ale przede wszystkim człowieka. Cele formacyjne są ważne i nie da się ich zastąpić modnymi hasłami, tak jak nie da się odejść od rozumnego czytania, odbioru tekstu. Można wykorzystywać jedynie metody bliższe uczniowi, „nowe" lub "przenicowane", dostosowane do danego czasu. Polonistyczny warsztat może być wzbogacony o nowe narzędzia. Jednak podstawowy „korpus" ma charakter ponadczasow…
Pulsed flow-through cultivation of Margaritifera margaritifera : effects of water source and food quantity on the survival and growth of juveniles
2020
AbstractConservation of the endangered freshwater pearl mussel (FPM) includes artificially rearing juveniles, but the pulsed flow-through (PFT) method, enabling the continuous renewal of water and food in culture containers, has not been applied to FPM. This study tested the PFT method in culture of FPM juveniles, and the effect of water source (tap vs well water) and food concentration (mixture of commercial phytoplankton products) on the survival and growth of juveniles. Beaker-specific survival rates varied from 0 to 100% (mean: 34%) and from 0 to 58% (mean: 16%) in the 1st (2-week) and 2nd (10-week) experiment, respectively. In the 1st experiment, juveniles attained statistically signif…
Bunker culturel : la régénération du patrimoine militaire urbain à Saint-Nazaire
2011
Au cours des deux dernières décennies Saint-Nazaire a relancé son développement sans se référer nécessairement aux modèles des métropoles européennes. Concentrées autour de la zone portuaire, près de la base sous-marine allemande, les nouvelles opérations urbaines ont contribué à définir un important projet touristique et culturel. La spécificité symbolique et la valorisation du patrimoine militaire ont permis à Saint-Nazaire de montrer que l’identité d’une ville pouvait activer sa croissance.Over the last two decades, the port city of Saint-Nazaire has encouraged urban redevelopment without necessarily following the models suggested by other European cities. An important cultural and touri…
Pop-Up Architecture as Urban Regeneration
2016
Recent ideas in urban planning, conceptualized e.g., as New Urbanism, emphasize the humane point of view of the city. The focus of these ideas is on the citizens and their experiences of feeling comfortable and at home in the urban space; people´s possibilities of spending leisure time in the city centre; and enabling the encounter of different people in the city space in order to bring the inner city to life. To revitalize the less used, unused, or decayed city spaces by using them as venues for diverse cultural activities is a part of these ideas. The means of urban regeneration often rely on ambitious and permanent transformations of the urban space, such as constructing cultural infrast…
Le città e l'Europa
2014
L’elaborazione dell’Agenda Urbana Europea ha, insieme all’Agenda Urbana Nazionale dei Paesi dell’Unione, lo scopo di integrare le strategie dei diversi territori ed accrescere il dinamismo economico. Laddove manchi la sinergia fra tali livelli operativi diminuisce la potenzialità e l’efficacia delle politiche urbane. Da una riflessione critica sul flop della candidatura della città di Palermo al titolo di Capitale Europea della Cultura è possibile estrapolare spunti per una buona costruzione di politiche urbane nell'ambito di un'Agenda Urbana Nazionale e per progetti competitivi nei cicli di programmazione europea.
Lithic Management in the Chassey Culture Neolithic
2009
The integrated technological approach of the lithic industries in Southern France Chassey culture and neighbouring cultures is a way to highlight a complex organisation of space. The development of long distance diffusion networks of lithic products from western Provence creates interdependence between producing-exporting sites and receiving-consuming sites. The analysis of their functioning, from raw material sources until remote consuming sites, is undergone on various scales (from supra-regional to local), through lithic technology and use wear analysis.