Search results for " cyclodextrin"

AQUEOUS MIXTURES OF A THERMOSENSITIVE CATIONIC BLOCK COPOLYMER AND CYCLODEXTRINS. INCLUSION COMPLEXES FORMATION.

2010

Back Cover: Water Structure Recovery in Chaotropic Anion Recognition: High-Affinity Binding of Dodecaborate Clusters to γ-Cyclodextrin (Angew. Chem. …

2015

Two components hydrogels formed by host-guest interactions

Stabilization of unilamellar catanionic vesicles induced by β-cyclodextrins: A strategy for a tunable drug delivery depot.

2018

The limited stability of catanionic vesicles has discouraged their wide use for encapsulation and controlled release of active substances. Their structure can easily break down to form lamellar phases, micelles or rearrange into multilamellar vesicles, as a consequence of small changes in their composition. However, despite the limited stability, catanionic vesicles possess an attractive architecture, which is able to efficiently encapsulate both hydrophobic and hydrophilic molecules. Therefore, improving the stability of the vesicles, as well as the control on unilamellar structures, are prerequisites for their wider application range. This study focuses on the impact of β-cyclodextrins fo…

Highly Sensitive Detection of Naphthalene in Solvent Vapor Using a Functionalized PBG Refractive Index Sensor

2012

We report an optical refractive index sensor system based on a planar Bragg grating which is functionalized by substituted γ-cyclodextrin to determine low concentrations of naphthalene in solvent vapor. The sensor system exhibits a quasi-instantaneous shift of the Bragg wavelength and is therefore capable for online detection. The overall shift of the Bragg wavelength reveals a linear relationship to the analyte concentration with a gradient of 12.5 ± 1.5 pm/ppm. Due to the spectral resolution and repeatability of the interrogation system, this corresponds to acquisition steps of 80 ppb. Taking into account the experimentally detected signal noise a minimum detection limit of 0.48 ± 0.05 pp…

Modulating the Self-assembly of Block Copolymers by Selective Cyclodextrins

2009

Use of 2 hydroxypropyl-beta-cyclodextrin therapy in two adult Niemann Pick Type C patients

2016

Ring opening polymerization of cyclic esters with metal free catalysts

2012

Temperature-responsive inclusion complex of cationic PNIPAAM diblock copolymer and γ-cyclodextrin

2012

Aqueous mixtures of γ-cyclodextrin (γ-CD) and the thermosensitive cationic diblock copolymer poly(N-isopropylacrylamide)-b-poly(3-acrylamidopropyl)trimethylammonium chloride (PNIPAAM24-b-PAMPTAM(+)9) or the PNIPAAM homopolymer PNIPAAM47 have been investigated using various experimental methods. Solid γ-CD–polymer inclusion complexes (pseudopolyrotaxanes) form at ambient temperatures in fairly concentrated CD solutions. The NMR measurements showed that the stoichiometry of the inclusion complexes is close to two NIPAAM units per CD molecule. The cationic block of the copolymer is not incorporated into the CD cavity. Synchrotron radiation X-ray diffraction spectra of the solid inclusion compl…

Porphyrin tributyltin(IV) complexes for a novel approach in the tratment of human melanoma

2012

Melanoma is the most deadly form of skin cancer, largely refractory to existing therapies. The study of porphyrin derivatives as potential anti-tumor drugs has been an interesting field of investigation in the last years. Recently, a photo-independent cytotoxic effect of (Bu3Sn)4TPPS in the blocking melanoma cell proliferation an inducing a morphology cell change was investigated.[1] Amphiphilic CD (ACyD) provides more water soluble and adaptable nanovectors through modulation of the balance between hydrophobic and hydrophilic chains at both CD sides. ACyD can be conveniently tailored by covalently appending fluorescent label or receptor-targeting glycosyl- groups and can encapsulate conven…