Search results for " data"
showing 10 items of 7516 documents
Pathophysiology of vascular dementia.
2009
The concept of Vascular Dementia (VaD) has been recognized for over a century, but its definition and diagnostic criteria remain unclear.Conventional definitions identify the patients too late, miss subjects with cognitive impairment short of dementia, and emphasize consequences rather than causes, the true bases for treatment and prevention. We should throw out current diagnostic categories and describe cognitive impairment clinically and according to commonly agreed instruments that document the demographic data in a standardized manner and undertake a systematic effort to identify the underlying aetiology in each case.Increased effort should be targeted towards the concept of and criteri…
Meeting the Challenges of High-Dimensional Single-Cell Data Analysis in Immunology
2019
Recent advances in cytometry have radically altered the fate of single-cell proteomics by allowing a more accurate understanding of complex biological systems. Mass cytometry (CyTOF) provides simultaneous single-cell measurements that are crucial to understand cellular heterogeneity and identify novel cellular subsets. High-dimensional CyTOF data were traditionally analyzed by gating on bivariate dot plots, which are not only laborious given the quadratic increase of complexity with dimension but are also biased through manual gating. This review aims to discuss the impact of new analysis techniques for in-depths insights into the dynamics of immune regulation obtained from static snapshot …
Usages des technologies par les élèves professeurs : analyse à partir de questionnaires
2005
This article studies the appropriation and the uses of technologies by French student teachers. The methodology used is based on the analysis of answers to questionnaires submitted to the trainees of four “instituts universitaires de formation des maîtres” (teacher training schools). The results obtained tend to prove that outside the classroom trainee teachers are today well equipped and really competent as far as personal and professional uses of technologies are concerned. However, it appears that these skills are not taken advantage of in the presence of the pupils.
Farm Entrepreneurs’ Intentions to Develop Pluriactive Business Activities in Finland
2015
We contribute to the entrepreneurial intentions literature by applying the theory of planned behaviour and resource-based views to the model of active entrepreneurs’ intention to develop their pluriactive businesses. Using our 2012 survey data from farm firms in Finland, we address the limited focus on active entrepreneurs and their intentions to develop on-going income-generating, off-farm related business activities. We found that attitudinal proxy antecedents such as innovation, cooperation and growth for pluriactivity differ for active and non-active entrepreneurs and with respect to the entrepreneurs’ age and production line and innovation behaviour. Praca wnosi wkład w badania nad int…
Assessment of nonnegative matrix factorization algorithms for electroencephalography spectral analysis.
2020
AbstractBackgroundNonnegative matrix factorization (NMF) has been successfully used for electroencephalography (EEG) spectral analysis. Since NMF was proposed in the 1990s, many adaptive algorithms have been developed. However, the performance of their use in EEG data analysis has not been fully compared. Here, we provide a comparison of four NMF algorithms in terms of accuracy of estimation, stability (repeatability of the results) and time complexity of algorithms with simulated data. In the practical application of NMF algorithms, stability plays an important role, which was an emphasis in the comparison. A Hierarchical clustering algorithm was implemented to evaluate the stability of NM…
A web-based collection of genotype-phenotype associations in hereditary recurrent fevers from the Eurofever registry
2017
PubMed ID: 29047407
Impact of the terrestrial reference frame on the determination of the celestial reference frame.
2022
Currently three up-to-date Terrestrial Reference Frames (TRF) are available, the ITRF2014 from IGN, the DTRF2014 from DGFI-TUM, and JTRF2014 from JPL. All use the identical input data of space-geodetic station positions and Earth orientation parameters, but the concept of combining these data is fundamentally different. The IGN approach is based on the combination of technique solutions, while the DGFI is combining the normal equation systems. Both yield in reference epoch coordinates and velocities for a global set of stations. JPL uses a Kalman filter approach, realizing a TRF through weekly time series of geocentric coordinates. As the determination of the CRF is not independent of the T…
Approaching electrical tomography
2009
A general approach to electrical tomography is here described, based on the distribution of the experimental data to the set of voxels in which the subsoil has been divided. This approach utilizes the sensitivity coefficients as factors of the convolution procedure to execute the back projection of the data, to obtain the 3D pictures of the subsoil. A subsequent probabilistic filtering technique is described to improve the pictures in view of sharp boundary models. Some models are finally presented, mostly regarding cubic buried anomalies as well as pipe-shaped and L-shaped anomalies.
SNPs detection by eBWT positional clustering
2019
Sequencing technologies keep on turning cheaper and faster, thus putting a growing pressure for data structures designed to efficiently store raw data, and possibly perform analysis therein. In this view, there is a growing interest in alignment-free and reference-free variants calling methods that only make use of (suitably indexed) raw reads data. We develop the positional clustering theory that (i) describes how the extended Burrows–Wheeler Transform (eBWT) of a collection of reads tends to cluster together bases that cover the same genome position (ii) predicts the size of such clusters, and (iii) exhibits an elegant and precise LCP array based procedure to locate such clusters in the e…
Challenges in dental statistics: survey methodology topics
2022

 This paper gathers some contributions concerning survey methodology in dental research, as discussed during the first Workshop of the SISMEC STATDENT working group on statistical methods and applications in dentistry, held in Ancona on the 28th September 2011.
 The first contribution deals with the European Global Oral Health Indicators Development (EGOHID) Project which proposed a comprehensive and standardized system of epidemiological tools (questionnaires and clinical forms) for national data collection on oral health in Europe. The second contribution regards the design and conduct of trials to evaluate the clinical efficacy and safety of toothbrushes and mouthrinses. Final…