Search results for " effect"
showing 10 items of 7524 documents
Modeling cost-effectiveness and health gains of a âuniversalâ versus âprioritizedâ hepatitis C virus treatment policy in a real-life cohort
2017
We evaluated the cost-effectiveness of two alternative direct-acting antiviral (DAA) treatment policies in a real-life cohort of hepatitis C virusâinfected patients: policy 1, âuniversal,â treat all patients, regardless of fibrosis stage; policy 2, treat only âprioritizedâ patients, delay treatment of the remaining patients until reaching stage F3. A liver disease progression Markov model, which used a lifetime horizon and health care system perspective, was applied to the PITER cohort (representative of Italian hepatitis C virusâinfected patients in care). Specifically, 8,125 patients naive to DAA treatment, without clinical, sociodemographic, or insurance restrictions, were us…
Accidental poisoning with Aconitum: Case report and review of the literature
2020
Abstract Aconitine intoxication by ingestion of Aconitum roots can lead to ventricular tachycardia and cardiac arrest and provides an example of the potential effect of self‐medication. Educational campaigns should be implemented to contain acute intoxications caused by herbal‐derived products.
Hidden attractors in electromechanical systems with and without equilibria
2016
This paper studies hidden oscillations appearing in electromechanical systems with and without equilibria. Three different systems with such effects are considered: translational oscillator-rotational actuator, drilling system actuated by a DC-motor and drilling system actuated by induction motor. We demonstrate that three systems experience hidden oscillations in sense of mathematical definition. While some of these hidden oscillations can be easily seen in natural physical experiments, the localization of others requires special efforts. peerReviewed
Cannabinoid 1/2 Receptor Activation Induces Strain-Dependent Behavioral and Neurochemical Changes in Genetic Absence Epilepsy Rats From Strasbourg an…
2022
Childhood absence epilepsy (CAE) is characterized by absence seizures, which are episodes of lack of consciousness accompanied by electrographic spike-wave discharges. About 60% of children and adolescents with absence seizures are affected by major neuropsychological comorbidities, including anxiety. Endocannabinoids and monoamines are likely involved in the pathophysiology of these CAE psychiatric comorbidities. Here, we show that the synthetic cannabinoid receptor type 1/2 (CB1/2R) agonist WIN 55,212-2 (2 mg/kg) has a strain-dependent effect on anxiety-like and motor behavior when assess in the hole board test and cerebral monoaminergic levels in Genetic Absence Epilepsy Rats from Strasb…
Of Friends and Foes in Organizations: A Theoretical Perspective Upon Performance at Work
2014
Abstract The present paper highlights, from a theoretical perspective, the main challenges which aim work performance, inside meta- analytical research studies in organizations, focusing, especially, on factors and organizational concepts, directly related to performance and their relations within. Results show that, in most cases, human resources oriented management resides in an increase of performance at work. In this manner, team effectiveness, group size and proactive behavior determine and influence the levels of work performance, from a positive perspective, whilst turnover is widely associated with a negative view.
Processing Mechanism of Chinese Verbal Jokes : Evidence from ERP and Neural Oscillations
2019
The cognitive processing mechanism of humor refers to how the system of neural circuitry and pathways in the brain deals with the incongruity in a humorous manner. The past research has revealed different stages and corresponding functional brain activities involved in humor-processing in terms of time and space dimensions, highlighting the effects of the time windows of about 400 ms, 600 ms, and 900 ms. However, much less is known about humor processing in light of the frequency dimension. A total of 36 Chinese participants were recruited in this experiment, with Chinese jokes, nonjokes, and nonsensical sentences used as the stimuli. The experimental results showed that there were signific…
Short-term effects of potassium fertilization on the hydraulic conductance of Laurus nobilis L.
2011
This study reports experimental evidence on the effect of short term potassium fertilization on potassium uptake, tissue concentration and hydraulic conductance of pot-grown laurel plants. Potassium uptake and loading into the xylem of laurel seedlings increased within 24 h from fertilization. Potassium was not accumulated in roots and leaves, but the [K+] of xylem sap was 80% higher in fertilized plants (+K) than in potassium starved plants (-K), likely as a result of recirculation between xylem and phloem. This increase in xylem sap [K+] resulted in a 45% increase in transpiration rate, a 30% increase in plant hydraulic conductance (Kplant) and a 120% increase in leaf specific conductivit…
Crystal structure and Hirshfeld surface analysis of (2E)-3-(3-bromo-4-fluorophenyl)-1-(3,4-dimethoxyphenyl)prop-2-en-1-one
2018
The title compound is constructed from two aromatic rings (3-bromo-4-fluorophenyl and 3,4-dimethoxyphenyl), which are linked by a C=C—C(=O)—C enone bridge and form a dihedral angle of 17.91 (17)°. In the crystal, molecules are linked by C—H⋯O hydrogen bonds enclosing rings of (14) graph-set motif to form layers parallel to (10).
Co-reductive fabrication of carbon nanodots with high quantum yield for bioimaging of bacteria
2018
A simple and straightforward synthetic approach for carbon nanodots (C-dots) is proposed. The strategy is based on a one-step hydrothermal chemical reduction with thiourea and urea, leading to high quantum yield C-dots. The obtained C-dots are well-dispersed with a uniform size and a graphite-like structure. A synergistic reduction mechanism was investigated using Fourier transform infrared spectroscopy and X-ray photoelectron spectroscopy. The findings show that using both thiourea and urea during the one-pot synthesis enhances the luminescence of the generated C-dots. Moreover, the prepared C-dots have a high distribution of functional groups on their surface. In this work, C-dots proved …