Search results for " encephalitis"

showing 10 items of 35 documents

Unusual MRI findings in an immunocompetent patient with EBV encephalitis: a case report.

2011

Abstract Blackground It is well-known that Epstein-Barr virus (EBV) can affect the central nervous system (CNS). Case presentation Herein the authors report unusual timely Magnetic Resonance Imaging (MRI) brain scan findings in an immunocompetent patient with EBV encephalitis. Diffusion weighted MRI sequence performed during the acute phase of the disease was normal, whereas the Fast Relaxation Fast Spin Echo T2 image showed diffuse signal intensity changes in white matter. The enhancement pattern suggested an inflammatory response restricted to the brain microcirculation. Acyclovir and corticosteroid therapy was administered. After three weeks, all signal intensities returned to normal and…

AdultMalePathologymedicine.medical_specialtySettore MED/07 - Microbiologia E Microbiologia ClinicaEpstein-Barr virus encephalitis MRI Diffusion-weighted imaginglcsh:Medical technologyMononucleosisSettore MED/17 - Malattie InfettiveencephalitisCentral nervous systemCase Reportmedicine.disease_causeWhite matterImmunocompromised HostNeuroimagingmedicineHumansEpstein-Barr virusRadiology Nuclear Medicine and imagingInfectious Mononucleosismedicine.diagnostic_testbusiness.industrySettore MED/37 - NeuroradiologiaMagnetic resonance imagingmedicine.diseaseEpstein–Barr virusMagnetic Resonance Imagingmedicine.anatomical_structurelcsh:R855-855.5Radiology Nuclear Medicine and imagingDiffusion-weighted imagingbusinessEncephalitisDiffusion MRIMRIBMC medical imaging
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Bickerstaff brainstem encephalitis. A case report

1992

A 33-year-old woman three weeks after a febrile illness presented with a syndrome of ophthalmoplegia, ataxia and areflexia (SOAA) that characterizes clinically both Bickerstaff and Miller Fisher syndromes. The normality of the electrophysiological tests performed, the CSF findings and the magnetic resonance images proved that the syndrome stemmed from brainstem pathology.

Adultmedicine.medical_specialtyPathologyAtaxiaNeurologyBickerstaff brainstem encephalitisDermatologyotorhinolaryngologic diseasesmedicineHumansNeuroradiologyOphthalmoplegiaReflex Abnormalmedicine.diagnostic_testbusiness.industryGeneral NeuroscienceFebrile illnessMagnetic resonance imagingSyndromeGeneral Medicinemedicine.diseaseMagnetic Resonance ImagingPsychiatry and Mental healthEncephalitisAtaxiaFemaleNeurology (clinical)NeurosurgeryBrainstemmedicine.symptombusinessBrain StemThe Italian Journal of Neurological Sciences
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Cross-reactivity of a pathogenic autoantibody to a tumor antigen in GABA(A) receptor encephalitis

2021

Encephalitis associated with antibodies against the neuronal gamma-aminobutyric acid A receptor (GABA A -R) is a rare form of autoimmune encephalitis. The pathogenesis is still unknown but autoimmune mechanisms were surmised. Here we identified a strongly expanded B cell clone in the cerebrospinal fluid of a patient with GABA A -R encephalitis. We expressed the antibody produced by it and showed by enzyme-linked immunosorbent assay (ELISA) and immunohistochemistry that it recognizes the GABA A -R. Patch-clamp recordings revealed that it tones down inhibitory synaptic transmission and causes increased excitability of hippocampal CA1 pyramidal neurons. Thus, the antibody likely contributed to…

AutoimmunityCross Reactionsmedicine.disease_causeCross-reactivityAutoantigensPathogenesisAutoimmune Diseases of the Nervous SystemAntigens NeoplasmmedicineHumansAutoantibodiesAutoimmune encephalitisB-LymphocytesMultidisciplinarybiologyPyramidal CellsAutoantibodyGABA-A-receptor encephalitis autoantibody autoimmune encephalitis epilepsy paraneoplastic encephalitisBiological Sciencesmedicine.diseaseReceptors GABA-ATumor antigennervous systemImmunologybiology.proteinImmunohistochemistryEncephalitisDisease SusceptibilityAntibodyEncephalitisBiomarkers
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Detection of tick-borne encephalitis virus in I. ricinus ticks collected from autumn migratory birds in Latvia.

2014

Birds have a potential of spreading ticks via bird migration routes. In this study, we screened 170 ticks removed during autumn 2010 from 55 birds belonging to 10 species for the presence of tick-borne encephalitis virus (TBEV). In total, TBEV RNA was detected in 14% of I. ricinus tick samples obtained from different birds species. The results of this study indicate the possible role of migrating birds in the dispersal of TBEV-infected ticks along the southward migration route.

Bird migrationBiologyTickMicrobiologyVirusEncephalitis Viruses Tick-BorneBirdsZoonosesparasitic diseasesmedicineAnimalsHumansIxodesBird DiseasesRicinusbacterial infections and mycosesmedicine.diseasebiology.organism_classificationVirologyLatviaTick-borne encephalitis virusInfectious DiseasesInsect ScienceBiological dispersalRNA ViralParasitologyAnimal MigrationArachnid VectorsSeasonsEncephalitisEncephalitis Tick-BorneTicks and tick-borne diseases
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Successful treatment of HSV encephalitis during pregnancy.

1989

A propos d'une femme presentant une grossesse de 23 semaines. Description des signes cliniques et electroencephalographiques. Les effets de l'aciclovir sur l'encephalite et sur l'evolution de la grossesse sont etudies

GynecologyAdultPregnancymedicine.medical_specialtyChemotherapybusiness.industrymedicine.medical_treatmentAcyclovirHerpes Simplexmedicine.diseasePregnancyImmunologymedicineGestationEncephalitisHumansFemaleNeurology (clinical)AciclovirHsv encephalitisPregnancy Complications InfectiousbusinessEncephalitismedicine.drugNeurology
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Misdiagnosis and pitfalls in Panayiotopoulos syndrome

2019

Abstract Panayiotopoulos syndrome (PS) is a frequent (6% among children of 1–15 years) and benign epileptic syndrome, characterized by predominantly autonomic symptoms (emesis, pallor, flushing, cyanosis, mydriasis/miosis, cardiorespiratory and thermoregulatory alterations, incontinence of urine and/or feces, hypersalivation, and modifications of intestinal motility) associated with simple motor focal seizures, which can be followed by secondary generalization. Panayiotopoulos syndrome can be extremely insidious, because it can mimic several condition, such as gastroenteritis, gastroesophageal reflux disease, encephalitis, syncope, migraine, sleep disorders, or even metabolic diseases. This…

HypersalivationMaleSleep Wake DisordersPediatricsmedicine.medical_specialtyVomitingMigraine DisordersencephalitisDiseasegastrointestinal disordersPallorSyncope Encephalitis03 medical and health sciencesBehavioral NeuroscienceEpilepsy0302 clinical medicinePleiotropismMedicineHumans030212 general & internal medicineDiagnostic ErrorsChildcyclic vomiting syndrome; gastrointestinal disorders; panayiotopoulos syndrome; sleep disorders; syncope; encephalitisbusiness.industryCyclic vomiting syndromeElectroencephalographymedicine.diseasePanayiotopoulos syndromecyclic vomiting syndromeNeurologyMigrainepanayiotopoulos syndromeChild PreschoolsyncopeGastroesophageal RefluxSettore MED/26 - NeurologiaFemalesleep disordersNeurology (clinical)Epilepsies Partialmedicine.symptombusiness030217 neurology & neurosurgery
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INTERNATIONAL COLLABORATIVE PROJECT ON TICK-BORNE ENCEPHALITIS IN THE BARENTS REGION

2018

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Infectious DiseasesGeographyImmunologyTick-borne encephalitismedicineImmunology and AllergyInfectious and parasitic diseasesRC109-216medicine.diseaseVirologyRussian Journal of Infection and Immunity
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Untersuchungen zur Bedeutung der Frühsommer-Meningoenzephalitis in Rheinland-Pfalz

2002

Within the scope of a prospective clinical study during 2001 in Rhineland-Palatinate specimen from sera and cerebrospinal fluids of 163 patients with suspected meningitis were controlled in an enzyme immunoassay concerning a TBE infection. Questionable results were checked via a neutralisation test. In no case such an infection was confirmed. No virus specific nucleic acids could be detected in 998 nymphs and adults of Ixodes ricinus in an additional investigation in 2000. Therefore Rhineland-Palatinate has to be considered as a region with low virus prevalence. A general recommendation for vaccination is not necessary.

Ixodes ricinusbiologymedicine.diagnostic_testbusiness.industryPublic Health Environmental and Occupational HealthTick-borne encephalitismedicine.diseasebiology.organism_classificationVirologyNeutralizationVirusVaccinationImmunoassayImmunologymedicineViral diseasebusinessMeningitisDas Gesundheitswesen
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Relapse risk factors in anti-N-methyl-D-aspartate receptor encephalitis

2019

Aim: To identify factors that may predict and affect the risk of relapse in anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis. Method: This was a retrospective study of an Italian cohort of patients with paediatric (≤18y) onset anti-NMDAR encephalitis. Results: Of the 62 children included (39 females; median age at onset 9y 10mo, range 1y 2mo–18y; onset between 2005 and 2018), 21 per cent relapsed (median two total events per relapsing patient, range 2–4). Time to first relapse was median 31.5 months (range 7–89mo). Severity at first relapse was lower than onset (median modified Rankin Scale [mRS] 3, range 2–4, vs median mRS 5, range 3–5; admission to intensive care unit: 0/10 vs 3/10…

Male030506 rehabilitationGastroenterologyCohort Studies0302 clinical medicineRetrospective StudieModified Rankin ScaleRecurrenceRisk FactorsChildrelapseAnti-N-Methyl-D-Aspartate Receptor EncephalitisHazard ratioItalyChild PreschoolCohortanti‐N‐methyl‐D‐aspartate receptor encephalitisFemale0305 other medical scienceEncephalitisHumanCohort studymedicine.medical_specialtyAdolescentSocio-culturaleanti-NMDAR antibodies03 medical and health sciencesanti-NMDARDevelopmental NeuroscienceInternal medicinemedicineAdolescent; Anti-N-Methyl-D-Aspartate Receptor Encephalitis; Child; Child Preschool; Cohort Studies; Female; Humans; Infant; Italy; Male; Recurrence; Retrospective Studies; Risk FactorsHumansPreschoolSurvival analysisRetrospective StudiesAutoimmune encephalitisbusiness.industryInfantRetrospective cohort studymedicine.diseaseanti-NMDAR antibodies autoimmune encephalitis anti‐N‐methyl‐D‐aspartate receptor encephalitisautoimmune encephalitisAnti-N-methyl-D-aspartate receptor encephalitis anti-NMDAR autoimmune encephalitis relapseAnti-N-Methyl-D-Aspartate Receptor EncephalitiPediatrics Perinatology and Child HealthNeurology (clinical)Cohort Studiebusiness030217 neurology & neurosurgery
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Two laboratory-confirmed cases of Japanese encephalitis imported to Germany by travelers returning from Southeast Asia

2011

Japanese encephalitis virus is the leading cause of encephalitis in Asia and parts of the Pacific. Despite the high number of symptomatic infections in endemic countries, clinical disease in travelers is rare. However, an increasing number of imported infections from popular holiday destinations in Southeast Asia have been recorded in the past few years, including serious disease courses in short-term travelers. Here we report two severe, non-fatal cases in tourists, who returned from a long-time stay in Thailand and a short-term trip to Bali, Indonesia, respectively. Recommendations for vaccination and pre-travel advice are discussed.

MaleVeterinary medicineDestinationsAntibodies ViralSoutheast asiaGermanyVirologyHumansMedicineEncephalitis JapaneseSocioeconomicsAgedTravelbiologybusiness.industryMiddle AgedJapanese encephalitisThailandbiology.organism_classificationClinical diseasemedicine.diseaseVaccinationFlavivirusInfectious DiseasesImmunoglobulin MIndonesiaImmunoglobulin GFemalebusinesshuman activitiesEncephalitisJournal of Clinical Virology
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