Search results for " investigation"

showing 10 items of 289 documents

Phytosterol plasma concentrations and coronary heart disease in the prospective Spanish EPIC cohort

2010

Phytosterol intake with natural foods, a measure of healthy dietary choices, increases plasma levels, but increased plasma phytosterols are believed to be a coronary heart disease (CHD) risk factor. To address this paradox, we evaluated baseline risk factors, phytosterol intake, and plasma noncholesterol sterol levels in participants of a case control study nested within the European Prospective Investigation into Cancer and Nutrition (EPIC) Spanish cohort who developed CHD (n = 299) and matched controls (n = 584) who remained free of CHD after a 10 year follow-up. Sitosterol-to-cholesterol ratios increased across tertiles of phytosterol intake (P = 0.026). HDL-cholesterol level increased, …

AdultMalecampesterolmedicine.medical_specialtyCampesterolPopulationCoronary DiseaseLathosterolQD415-436lathosterolBiochemistryplant sterolsCohort Studieschemistry.chemical_compoundEndocrinologyRisk FactorsInternal medicineHumansMedicineProspective StudiesRisk factoreducationProspective cohort studyAgededucation.field_of_studyCholesterolbusiness.industrycholesterolPhytosterolsCell BiologyEuropean Prospective Investigation into Cancer and NutritionMiddle AgedDietEuropean Prospective Investigation into Cancer and NutritionEndocrinologysitosterolchemistrySpainCase-Control StudiesNested case-control studyFemalelipids (amino acids peptides and proteins)Patient-Oriented and Epidemiological ResearchbusinessJournal of Lipid Research
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Association of Anorexia Nervosa With Risk of Cancer: A Systematic Review and Meta-analysis

2019

This systematic review and meta-analysis evaluates the association of anorexia nervosa with the cancer incidence and mortality among study populations with anorexia nervosa compared with the general population or those without anorexia nervosa.

AdultMalemedicine.medical_specialtyAnorexia NervosaPopulationbehavioral disciplines and activitiesYoung Adult03 medical and health sciences0302 clinical medicineBreast cancerNeoplasmsInternal medicineObservational studymental disordersHumansMedicine030212 general & internal medicineSex DistributionYoung adulteducationOriginal InvestigationAgedCancereducation.field_of_studybusiness.industryResearchMortality ratedigestive oral and skin physiologyCancerGeneral MedicineMiddle Agedmedicine.disease3. Good healthOnline OnlyMeta-analysisOncologyAnorexia nervosa (differential diagnoses)030220 oncology & carcinogenesisMeta-analysisSystematic reviewFemaleEpidemiologic Methodsbusinesshormones hormone substitutes and hormone antagonistsCohort study
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Overview of ambulatory blood pressure monitoring in childhood and pregnancy.

2001

Despite the fact that the study and applicability of ambulatory blood pressure in children and pregnant women share characteristics which limit the potential development of knowledge for their use, advances produced in the last few years provided the present knowledge regarding the significance and the potential use of ambulatory blood pressure in children and in the pregnant women. In children ambulatory blood pressure monitoring is useful for the diagnosis of mild hypertensives, assessment of refractory hypertension, therapeutic trials with antihypertensive drugs, and clinical investigation when BP is one of the parameters to be taken into account and/or when subtle BP abnormalities are t…

AdultMalemedicine.medical_specialtyPediatricsAmbulatory blood pressurePregnancy Complications CardiovascularAssessment and DiagnosisPre-EclampsiaPregnancyClinical investigationInternal MedicinemedicineHumansIntensive care medicineChildAdvanced and Specialized NursingPregnancybusiness.industryGeneral MedicineBlood Pressure Monitoring AmbulatoryReference Standardsmedicine.diseaseTherapeutic trialBlood pressureHypertensionFemaleCardiology and Cardiovascular MedicinebusinessBlood pressure monitoring
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Trends in Incidence and Transmission Patterns of COVID-19 in Valencia, Spain

2021

Importance Limited information on the transmission and dynamics of SARS-CoV-2 at the city scale is available. Objective To describe the local spread of SARS-CoV-2 in Valencia, Spain. Design, Setting, and Participants This single-center epidemiological cohort study of patients with SARS-CoV-2 was performed at University General Hospital in Valencia (population in the hospital catchment area, 364 000), a tertiary hospital. The study included all consecutive patients with COVID-19 isolated at home from the start of the COVID-19 pandemic on February 19 until August 31, 2020. Exposures Cases of SARS-CoV-2 infection confirmed by the presence of IgM antibodies or a positive polymerase chain reacti…

AdultMalemedicine.medical_specialtyPopulation01 natural sciencesDisease Outbreakslaw.inventionCohort Studies010104 statistics & probability03 medical and health sciences0302 clinical medicineCatchment Area HealthResidence CharacteristicsRisk FactorslawEpidemiologyDisease Transmission InfectiousmedicineHumans030212 general & internal medicine0101 mathematicseducationOriginal InvestigationAgedAged 80 and overeducation.field_of_studyGeographySARS-CoV-2ResearchIncidenceIncidence (epidemiology)COVID-19OutbreakGeneral MedicineMiddle Aged3. Good healthOnline OnlyTransmission (mechanics)GeographySpainRelative riskHousehold incomeFemalePublic HealthDemographyCohort studyJAMA Network Open
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Long-term Effects of Multimodal Treatment on Adult Attention-Deficit/Hyperactivity Disorder Symptoms: Follow-up Analysis of the COMPAS Trial.

2019

Key Points Question What are the long-term results of multimodal treatment for adult attention-deficit/hyperactivity disorder (ADHD) when comparing cognitive behavioral group psychotherapy (GPT) with individual clinical management (CM) in combination with either methylphenidate or placebo? Findings In this follow-up assessment of the Comparison of Methylphenidate and Psychotherapy in Adult ADHD Study (COMPAS), a multicenter randomized clinical trial, 256 adults participated in follow-up 1.5 years after the intervention ended. The severity of ADHD symptoms improved in all 4 prior treatment groups, with no significant difference found between GPT and CM, but methylphenidate was associated wit…

AdultMalemedicine.medical_specialtyRandomizationMedizinPlacebolaw.invention03 medical and health sciencesYoung Adult0302 clinical medicineRandomized controlled triallawRating scalemental disordersmedicineAttention deficit hyperactivity disorderHumansYoung adultOriginal InvestigationPsychiatryCognitive Behavioral Therapybusiness.industryResearchBeck Depression InventoryGeneral MedicineMiddle Aged16. Peace & justicemedicine.diseaseCombined Modality Therapy030227 psychiatry3. Good healthOnline OnlyTreatment OutcomeAttention Deficit Disorder with HyperactivityPhysical therapyClinical Global ImpressionMethylphenidateCentral Nervous System StimulantsFemalebusiness030217 neurology & neurosurgeryFollow-Up StudiesJAMA network open
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Association of Cesarean Delivery With Risk of Neurodevelopmental and Psychiatric Disorders in the Offspring: A Systematic Review and Meta-analysis.

2019

This systematic review and meta-analysis examines the association between birth by cesarean delivery and risk of neurodevelopmental and psychiatric disorders in the offspring compared with birth by vaginal delivery.

Adultmedicine.medical_specialtyAdolescentOffspringAutism Spectrum DisorderSensitivity and SpecificityYoung AdultPregnancyRisk FactorsmedicineElective Cesarean DeliveryAttention deficit hyperactivity disorderHumansPsychiatryChildreproductive and urinary physiologyOriginal InvestigationPsychiatrybusiness.industryVaginal deliveryCesarean SectionMental DisordersResearchGeneral MedicineOdds ratiomedicine.diseaseDelivery ObstetricEating disordersObservational Studies as TopicOnline OnlyAutism spectrum disorderAttention Deficit Disorder with HyperactivityNeurodevelopmental DisordersCase-Control StudiesChild PreschoolFemalebusinessCohort studyJAMA network open
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Unconventional Aeronautical Investigatory Methods: The Case of Alitalia Flight AZ 112

2021

Viene svelato scientificamente la causa del disastro aereo di Montagna Longa del 5 maggio 1972 Based on unconventional air investigation techniques, this book highlights the mysterious crash of Alitalia flight AZ 112 on 5 May 1972, which killed 115 people, and was blamed solely on pilot negligence. Its findings show the cause of the disaster was not actually related to any pilot negligence, but, rather, it was the result of a criminal act. It argues that this attack was a symptom of the geopolitical tensions in Italy and Europe in that decade. Based on unconventional air investigation techniques, this book highlights the mysterious crash of Alitalia flight AZ 112 on 5 May 1972

Aeronautical Investigation Aerodynamics Flight MechanicsInvestigazione aerea Aerodinamica Meccanica del voloSettore ING-IND/06 - Fluidodinamica
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Can personality predict retirement behaviour? A longitudinal analysis combining survey and register data from Norway.

2017

Published version of an article in the journal: European Journal of Ageing. Also available from the publisher at: http://dx.doi.org/10.1007/s10433-011-0212-6 This study investigates how far personality can predict the timing and routes of people’s retirement. It uses a large comprehensive Norwegian survey, with larger sample size than earlier related studies, providing estimates of personality based on the five-factor model. The survey data are matched with administrative data, allowing observations of retirement over the 2002–2007 period. The analysis distinguishes between the disability and the non-disability retirements. Retirement is investigated using discrete time, competing risk, log…

Agreeablenesslongitudinal dataHealth (social science)Extraversion and introversionVDP::Social science: 200::Psychology: 260media_common.quotation_subjectLogistic regressionNeuroticismretirementdisabilitypersonality traitsOpenness to experienceSurvey data collectionPersonalityfive factor modelGeriatrics and GerontologyBig Five personality traitsPsychologyDemographyClinical psychologymedia_commonOriginal InvestigationEuropean journal of ageing
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El proyecto mapa escolar de Valencia: Análisis de la zonificación educativa de la ciudad de Valencia

2018

The research project Mapa Escolar de Valencia (School Map of Valencia) was born out of an agreement between the City Council and the University of Valencia in order to carry out an investigation of the compulsory education system of the city and propose, if necessary, modifications to the current school zoning. The project is structured in several research areas. An analysis of the specialized scientific literature and public policies concerning education and schooling has been done, and it is currently analysing the evolution of quantitative and qualitative data on compulsory schooling in Valencia, its school zoning, the representations of education and the school climate in the city schoo…

Análisis de la zonificación educativa de la ciudad de Valencia de Madaria Escudero [1137-7038 8537 Arxius de sociologia 514142 2018 39 6874491 El proyecto mapa escolar de Valencia]zonificación escolardezoningMuñoz Rodríguezits school zoningVila LladosaValencia 129 142the representations of education and the school climate in the city schools. The main results of the research are presented in this article Mapa escolarschool zoningUNESCO::SOCIOLOGÍAmodifications to the current school zoning. The project is structured in several research areas. An analysis of the specialized scientific literature and public policies concerning education and schooling has been doneGabaldón Estevanschool social segregation1137-7038 8537 Arxius de sociologia 514142 2018 39 6874491 El proyecto mapa escolar de Valencia: Análisis de la zonificación educativa de la ciudad de Valencia de Madaria EscuderoRequena i MoraSchoolingRodríguez VictorianoSandraJosé Manuel The research project Mapa Escolar de Valencia (School Map of Valencia) was born out of an agreement between the City Council and the University of Valencia in order to carry out an investigation of the compulsory education system of the city and proposeDanielsegregación escolareducation equityLuisescolarización:SOCIOLOGÍA [UNESCO]García De FezMarinaDavidequidad educativaif necessarydistrito únicoBorjaValenciaand it is currently analysing the evolution of quantitative and qualitative data on compulsory schooling in Valencia
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Association of plasma markers of cholesterol homeostasis with metabolic syndrome components. A cross-sectional study.

2011

Abstract Background and aims Increased plasma phytosterols, which reflect enhanced cholesterol absorption, have been related to an increased risk of cardiovascular disease (CVD). However, high CVD risk conditions, such as obesity, diabetes and the metabolic syndrome (MetS) have been associated with reduced cholesterol absorption. We investigated associations between plasma noncholesterol sterols and MetS components. Methods and results With a cross-sectional design, we related MetS components to plasma noncholesterol sterol-to-cholesterol ratios measured by gas chromatography in 674 dyslipidemic patients and 361 healthy subjects participating in a prospective cohort study. Plasma phytostero…

Apolipoprotein EAdultMalemedicine.medical_specialtyGenotypeEndocrinology Diabetes and MetabolismMedicine (miscellaneous)LathosterolBiologychemistry.chemical_compoundHigh-density lipoproteinApolipoproteins ERisk FactorsInternal medicineDiabetes mellitusmedicineHomeostasisHumansProspective StudiesProspective cohort studyMetabolic SyndromeNutrition and DieteticsPhytosterolsOdds ratioMiddle Agedmedicine.diseaseLipid MetabolismSitosterolsEuropean Prospective Investigation into Cancer and NutritionEndocrinologyCholesterolCross-Sectional StudiesPhenotypechemistryCardiovascular Diseaseslipids (amino acids peptides and proteins)FemaleMetabolic syndromeCardiology and Cardiovascular MedicineBiomarkersNutrition, metabolism, and cardiovascular diseases : NMCD
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