Search results for " jun"
showing 10 items of 611 documents
A Neurovascular Blood–Brain Barrier In Vitro Model
2014
The cerebral microvasculature possesses certain cellular features that constitute the blood-brain barrier (BBB) (Abbott et al., Neurobiol Dis 37:13-25, 2010). This dynamic barrier separates the brain parenchyma from peripheral blood flow and is of tremendous clinical importance: for example, BBB breakdown as in stroke is associated with the development of brain edema (Rosenberg and Yang, Neurosurg Focus 22:E4, 2007), inflammation (Kuhlmann et al., Neurosci Lett 449:168-172, 2009; Coisne and Engelhardt, Antioxid Redox Signal 15:1285-1303, 2011), and increased mortality. In vivo, the BBB consists of brain endothelial cells (BEC) that are embedded within a precisely regulated environment conta…
Wideband modeling of cascaded H-plane waveguide junctions using the generalised impedance matrix representation
2009
A strong interest in H-plane waveguide components composed of a large number of cascaded planar junctions is recently renewed. Therefore, the more efficient development of full-wave analysis tools of such devices is again receiving consideration, specially for its potential use within modern design tools. A novel technique for providing the wideband generalised impedance matrix representation of the inductive devices in the form of pole expansions, thus extracting the most expensive computations from the frequency loop is proposed. For such purpose, the whole device is first decomposed into simpler building blocks, i.e. planar junctions and uniform waveguides, which are modelled in terms of…
Noise and gain performance of PSA transistor series for personal communication systems vs. emitter number and operating conditions
1995
The booming market of communication system applications in the low microwave range put greater demands on the component performance at lower supply voltages and limited current consumption, as well as on production cost and integration level. In this work, we present the results of an extensive characterization activity carried out on several advanced polysilicon bipolar transistors as requested by the manufacturer. The devices were grouped according to their emitter finger number and were characterized over the 2-6 GHz frequency range in terms of noise, gain and scatterino parameters at different bias conditions. A comparative analysis has been performed to explore how the transistor perfo…
Melatonin alleviates Ochratoxin A-induced liver inflammation involved intestinal microbiota homeostasis and microbiota-independent manner.
2021
Melatonin (MEL) shows an anti-inflammatory effect and regulates intestinal microbiota communities in animals and humans; Ochratoxin A (OTA) induces liver inflammation through intestinal microbiota. However, it remains to know whether MEL alleviates the liver inflammation induced by OTA. In this study, MEL reversed various adverse effects induced by OTA. MEL recovered the swarming and motility of intestinal microbiota, decreased the accumulation of lipopolysaccharide (LPS), enhanced the tight junction proteins of jejunum and cecum segments; ultimately alleviated OTA-induced liver inflammation in ducks. However, it is worth noting that MEL still had positive effects on the OTA-exposed ducks a…
Polmunary epithelial barrier formation on biodegradable poly-L-lactic-acid (PLLA) membrane
2016
Aims: Investigation of epithelial barrier formation using PLLA membranes for application in bioengineering. Background: The development of functional and biocompatible substitutes for damaged tissue or organs is a major challenge in biomedical engineering. The epithelial barrier plays a central role in tissue homeostasis and immunity preventing damage and contamination of the interstitial tissues. Different in vitro models of the lung and intestinal epithelial barriers have been well characterized, however these tend to use non-biodegradable and/or poorly biocompatible scaffolds. Therefore, there is a need for better supports for epithelial cells for future applications in tissue engineerin…
The gap junctional intercellular communication is no prerequisite for the stabilization of xenobiotic metabolizing enzyme activities in primary rat l…
1995
In primary monocultures of adult rat liver parenchymal cells (PC), the activities of the xenobiotic metabolizing enzymes microsomal epoxide hydrolase (mEHb), soluble epoxide hydrolase (sEH), glutathione S-transferases (GST), and phenolsulfotransferase (ST) were reduced after 7 d to values below 33% of the initial activities. Furthermore, the gap junctional intercellular communication (GJIC), measured after microinjection by dye transfer, decreased from 90% on Day 1 to undetectable values after 5 d in monoculture. Co-culture of PC with nonparenchymal rat liver epithelial cells (NEC) increased (98% on Day 1) and stabilized (82% on Day 7) the homotypic GJIC of PC. Additionally, most of the mea…
La personalidad de las sociedades. Descripción y dinámica
2018
[EN] Extraversion is considered as the fundamental and basic dimension of personality from the Unique Trait Personality Theory [1]. Extraversion, as temperamental dimension, involves cognitive dimensions such as racionality and emotionality. Carl Jung¿s theory of types [2] states a complex dynamics among these dimensions. From this theory a typology of personality arises. Amigó [3] adapted Jung¿s theory to applye it to societies. A reflexion about history is given by the dynamics of societies through time. This approach starts from Jung's idea of the opposite dimensions that complement and imprint movement, and from Amigó's theory about societies survivance [4], which argues that crises cau…
Superconducting tunnel junction fabrication on three-dimensional topography via direct laser writing
2020
Superconducting junctions are widely used in multitude of applications ranging from quantum information science and sensing to solid-state cooling. Traditionally, such devices must be fabricated on flat substrates using standard lithographic techniques. In this study, we demonstrate a highly versatile method that allows for superconducting junctions to be fabricated on a more complex topography. It is based on maskless direct laser writing (DLW) two-photon lithography, which allows writing in 3D space. We show that high-quality normal metal-insulator-superconductor (NIS) tunnel junctions can be fabricated on top of a 20 $\mu$m tall three-dimensional topography. Combined with more advanced r…
Relation between the distance from the cementoenamel junction to the bone crest and the thickness of the facial bone in anterior maxillary teeth: A c…
2018
Background The purpose of this cross-sectional study was to evaluate radiologically, the relation between the distance from the cementoenamel junction (CEJ) to the facial bone crest (FBC), and the facial alveolar bone (FAB) width at maxillary anterior teeth. A further aim was to assess if the CEJ-FBC distance had an impact in the prevalence to find a FAB thickness greater than one mm. Material and Methods CBCT images were retrospectively obtained from the database of the Oral Surgery Unit of the University of Valencia. The teeth were divided in 3 groups according to the CEJ-FBC distance: Shorter (≤3mm), Middle (>3 ≤4.5 mm) and Larger (>4.5 mm). FAB thickness was measured by two different ex…
Horseshoe-shaped maps in chaotic dynamics of long Josephson junction driven by biharmonic signals
2000
Abstract A collective coordinate approach is applied to study chaotic responses induced by an applied biharmonic driven signal on the long Josephson junction influenced by a constant dc-driven field with breather initial conditions. We derive a nonlinear equation for the collective variable of the breather and a new version of the Melnikov method is then used to demonstrate the existence of Smale horseshoe-shaped maps in its dynamics. Additionally, numerical simulations show that the theoretical predictions are well reproduced. The subharmonic Melnikov theory is applied to study the resonant breathers. Results obtained using this approach are in good agreement with numerical simulations of …