Search results for " jun"
showing 10 items of 611 documents
REUTILIZACIÓN DE RESIDUOS DE PODA DE VID Y DE POSIDONIA OCEANICA EN LAS OBRAS DE BIOINGENIERÍA DEL PAISAJE
La popolazione mondiale è in continua espansione e la crescita demografica ed economica inducono allo sfruttamento progressivo dell’ambiente ed al depauperamento delle risorse naturali (acqua ed energia in particolare), con conseguenti impatti potenzialmente importanti sul cambiamento globale. Si rende, pertanto, necessaria ed urgente una più efficiente gestione delle risorse basata sulla rielaborazione di obiettivi sostenibili di politiche e strategie ambientali e sulla riduzione del consumo delle risorse, promuovendo la transizione da un modello di economia lineare ad uno circolare, costituito da un ciclo continuo di sviluppo positivo che preserva e migliora il capitale naturale, ottimizz…
The importance of tight junctions in the blood-brain barrier
2021
There are two barriers in the central nervous system (CNS) responsible for maintaining the homeostatic balance of the human body’s internal environment in relation to external conditions: the blood-brain barrier (BBB) and the blood-cerebrospinal fluid barrier (BCSFB). The blood-brain barrier is a physical barrier with a fixed location between the blood and the nervous tissue. Its basic structural elements include endothelial cells of the brain capillaries, astrocytes and pericytes. The blood-brain barrier is the barrier between the blood and neurons which isolates the central nervous system from the rest of the body in a unique manner. The blood-brain barrier is formed by astrocytes and per…
Cyclic adenosine monophosphate is a key component of regulatory T cell–mediated suppression
2007
Naturally occurring regulatory T cells (T reg cells) are a thymus-derived subset of T cells, which are crucial for the maintenance of peripheral tolerance by controlling potentially autoreactive T cells. However, the underlying molecular mechanisms of this strictly cell contact–dependent process are still elusive. Here we show that naturally occurring T reg cells harbor high levels of cyclic adenosine monophosphate (cAMP). This second messenger is known to be a potent inhibitor of proliferation and interleukin 2 synthesis in T cells. Upon coactivation with naturally occurring T reg cells the cAMP content of responder T cells is also strongly increased. Furthermore, we demonstrate that natur…
Keratin 7 expression as an early marker of reflux-related columnar mucosa without intestinal metaplasia in the esophagus
2009
BACKGROUND: The role of Barrett esophagus in carcinogenesis is widely accepted, but the significance of esophageal columnar mucosa without histological intestinal metaplasia, known as columnar-lined esophagus, is debated. MATERIAL/METHODS: We studied 128 patients free of Helicobacter pylori with reflux-related symptoms and columnar mucosa in the esophagus at endoscopy, 106 patients with Barrett esophagus (referred to as the Barrett group) and 22 patients without intestinal metaplasia (columnar group). Samples from 20 subjects free of H. pylori were used as controls. Immunostaining for keratin 7 (KRT7), keratin 20 (KRT20), caudal type homeobox 2 (CDX2), mucin 2, oligomeric mucus/gel-forming …
„Służba Boża Kościoła” Josefa Andreasa Jungmanna szerokie pojmowanie liturgii i jego krytyka
2018
W pierwszej części artykułu omówiono kontrowersyjne poglądy J.A. Jungmanna, uznające za liturgię szeroko rozumianą „służbę Bożą Kościoła”. Natomiast przedmiotem drugiej części opracowania jest polemika związana z reflksją Jungmanna odnośnie do definicji liturgii. Jungmann pozostawał wierny promowanemu przez siebie dość ogólnie sformułowanemu określeniu liturgii, podkreślając potrzebę właściwego pojmowania użytych w nim terminów. Wywołana jego stanowiskiem polemika jest przykładem merytorycznej dyskusji, wnoszącej godny przypomnienia wkład w rozwój myśli teologicznej.
Eklezjalny wymiar liturgii według Josefa Andreasa Jungmanna
2019
W artykule zaprezentowano refleksje J.A. Jungmanna dotyczące eklezjalnego wymiaru liturgii. Po przedstawieniu myśli tego autora, odnoszących się do kapłańskiej wspólnoty Kościoła jako podmiotu liturgii, omówiono jego uwagi na temat liturgii jako wyrazu wiary Kościoła. Odwołując się do historii, Jungmann podkreśla, że od samego początku liturgiczne formy z reguły miały wspólnotowy charakter i że w celebrowaniu liturgii uaktywnia się cały Kościół. Analiza liturgiczno-eklezjalnej refleksji Jungmanna pozwala uplasować go w gronie tych, którzy wnieśli istotny wkład w kształtowanie świadomości, że liturgia jest celebracją integralnie pojętej wspólnoty Kościoła, a także swoistym wyrażaniem i normą…
Josephson-based Threshold Detector for Lévy-Distributed Current Fluctuations
2019
We propose a threshold detector for Lévy-distributed fluctuations based on a Josephson junction. The Lévy-noise current added to a linearly ramped bias current results in clear changes in the distribution of switching currents out of the zero-voltage state of the junction. We observe that the analysis of the cumulative distribution function of the switching currents supplies information on both the characteristics' shape parameter α of the Lévy statistics. Moreover, we discuss a theoretical model, which allows characteristic features of the Lévy fluctuations to be extracted from a measured distribution of switching currents. In view of these results, this system can effectively find an appl…
Charge transport through spin-polarized tunnel junction between two spin-split superconductors
2019
We investigate transport properties of junctions between two spin-split superconductors linked by a spin-polarized tunneling barrier. The spin-splitting fields in the superconductors (S) are induced by adjacent ferromagnetic insulating (FI) layers with arbitrary magnetization. The aim of this study is twofold: On the one hand, we present a theoretical framework based on the quasiclassical Green's functions to calculate the Josephson and quasiparticle current through the junctions in terms of the different parameters characterizing it. Our theory predicts qualitative new results for the tunneling differential conductance, $dI/dV$, when the spin-splitting fields of the two superconductors are…
High dynamic resistance elements based on a Josephson junction array
2020
A chain of superconductor–insulator–superconductor junctions based on Al–AlOx–Al nanostructures and fabricated using conventional lift-off lithography techniques was measured at ultra-low temperatures. At zero magnetic field, the low current bias dynamic resistance can reach values of ≈1011 Ω. It was demonstrated that the system can provide a decent quality current biasing circuit, enabling the observation of Coulomb blockade and Bloch oscillations in ultra-narrow Ti nanowires associated with the quantum phase-slip effect.
Progress towards innovative and energy efficient logic circuits
2020
Abstract The integration of superconductive nanowire logic memories and energy efficient computing Josephson logic is explored. Nanowire memories are based on the integration of switchable superconducting nanowires with a suitable magnetic material. These memories exploit the electro-thermal operation of the nanowires to efficiently store and read a magnetic state. In order to achieve proper memory operation a careful design of the nanowire assembly is necessary, as well as a proper choice of the magnetic material to be employed. At present several new superconducting logic families have been proposed, all tending to minimize the effect of losses in the digital Josephson circuits replacing …