Search results for " lactate"

RETRACTED ARTICLE: Volume replacement with HES 130/0.4 may reduce the inflammatory response in patients undergoing major abdominal surgery

2003

Objectif : Verifier les effets du remplissage intravasculaire sur la reaction inflammatoire pendant une intervention chirurgicale majeure. Methode : Trente-six patients devant subir une intervention abdominale reglee ont ete repartis au hasard et ont recu soit de l'hydroxyethylamidon a 6 % (poids moleculaire moyen de 130 000 Dalton, degre de substitution de 0,4 ; n = 18, groupe HEA), soit une solution de Ringer-lactate (groupe RL ; n = 18) comme remplissage intravasculaire. Les liquides ont ete administres avant l'operation et, pendant 48 h a l'unite des soins intensifs. Le remplissage vasculaire dependait de parametres physiologiques. Les concentrations seriques d'interleukine (IL-6, IL-8 …

Cannabinoid control of brain bioenergetics: Exploring the subcellular localization of the CB1 receptor

2014

Brain mitochondrial activity is centrally involved in the central control of energy balance. When studying mitochondrial functions in the brain, however, discrepant results might be obtained, depending on the experimental approaches. For instance, immunostaining experiments and biochemical isolation of organelles expose investigators to risks of false positive and/or false negative results. As an example, the functional presence of cannabinoid type 1 (CB1) receptors on brain mitochondrial membranes (mtCB1) was recently reported and rapidly challenged, claiming that the original observation was likely due to artifact results. Here, we addressed this issue by directly comparing the procedures…

Photonic non-contact estimation of blood lactate level

2015

The ability to measure the blood lactate level in a non-invasive, non-contact manner is very appealing to the sports industry as well as the home care field. That is mainly because this substance level is an imperative parameter in the course of devolving a personal workout programs. Moreover, the blood lactate level is also a pivotal means in estimation of muscles' performance capability. In this manuscript we propose an optical non-contact approach to estimate the concentration level of this parameter. Firstly, we introduce the connection between the physiological muscle tremor and the lactate blood levels. Secondly, we suggest a photonic optical method to estimate the physiological tremo…

EFFECTS OF THREE DISTINCT PROTOCOLS OF FITNESS TRAINING ON BODY COMPOSITION STRENGTH AND BLOOD LACTATE

2008

THE COMPETITIVE DEMANDS OF ELITE MALE RINK HOCKEY

2013

The aim of this study was to simulate the activity pattern of rink hockey by designing a specific skate test (ST) to study the energy expenditure and metabolic responses to this intermittent high-intensity exercise and extrapolate the results from the test to competition. Six rink hockey players performed, in three phases, the 20-metre multi-stage shuttle roller skate test, a tournament match and the ST. Heart rate was monitored in all three phases. Blood lactate, oxygen consumption, ventilation and respiratory exchange ratio were also recorded during the ST. Peak HR was 190.7±7.2 beats · min(-1). There were no differences in peak HR between the three tests. Mean HR was similar between the …

Incidence, risk factors, and thrombotic load of pulmonary embolism in patients hospitalized for COVID-19 infection

2021

Summary Objective To determine the incidence, characteristics, and risk factors of pulmonary embolism (PE) among patients hospitalized for COVID-19. Patients and Methods We performed a prospective observational study of a randomly selected cohort of consecutive patients hospitalized for COVID-19 infection between March 8, 2020 through April 25, 2020. All eligible patients underwent a computed tomography pulmonary angiography independently of their PE clinical suspicion and were pre-screened for a baseline elevated D-dimer level. Results 119 patients were randomly selected from the 372 admitted to one tertiary hospital in Valencia (Spain) for COVID-19 infection during the period of study. Se…

LDHA-Associated Lactic Acid Production Blunts Tumor Immunosurveillance by T and NK Cells

2015

Elevated lactate dehydrogenase A (LDHA) expression is associated with poor outcome in tumor patients. Here we show that LDHA-associated lactic acid accumulation in melanomas inhibits tumor surveillance by T and NK cells. In immunocompetent C57BL/6 mice, tumors with reduced lactic acid production (Ldhalow) developed significantly slower than control tumors and showed increased infiltration with IFN-γ-producing T and NK cells. However, in Rag2-/-γc-/- mice, lacking lymphocytes and NK cells, and in Ifng-/- mice, Ldhalow and control cells formed tumors at similar rates. Pathophysiological concentrations of lactic acid prevented upregulation of nuclear factor of activated T cells (NFAT) in T and…

Effects of resistance training frequency on cardiorespiratory fitness in older men and women during intervention and follow-up.

2017

This study investigated the effects of resistance training (RT) performed with different frequencies, including a follow-up period, on cardiorespiratory fitness in healthy older individuals. Eighty-eight men and women (69 ± 3 years, 167 ± 9 cm and 78 ± 14 kg) were randomly placed into four groups: training one- (M1 = 11, W1 = 12), two- (M2 = 7, W2 = 14), or three- (M3 = 11, W3 = 13) times-per-week or a non-training control group (MCon = 11, WCon = 9). During months 1–3, all subjects trained two-times-per-week while during the subsequent 6 months, training frequency was set according to the group. Oxygen consumption (cycling economy: CE), gross efficiency (GE), blood lactate concentrations (…

Fatigue in a simulated cross-country skiing sprint competition

2009

The aim of this study was to assess fatigue during a simulated cross-country skiing sprint competition based on skating technique. Sixteen male skiers performed a 30-m maximal skiing speed test and four 850-m heats with roller skies on a tartan track, separated by 20 min recovery between heats. Physiological variables (heart rate, blood lactate concentration, oxygen consumption), skiing velocity, and electromyography (EMG) were recorded at the beginning of the heats and at the end of each 200-m lap during the heats. Maximal skiing velocity and EMG were measured in the speed test before the simulation. No differences were observed in skiing velocity, EMG or metabolic variables between the he…

Acute in vivo administration of a fish oil-containing emulsion improves post-ischemic cardiac function in n-3-depleted rats

2006

International audience; A novel i.v. lipid preparation (MCT:FO) containing 80% medium chain-triacylglycerols and 20% fish oil was recently developed to rapidly replenish cell membrane phospholipids with omega 3 (n-3) polyunsaturated fatty acids (PUFA). In regard of this property, we investigated the effect of a single i.v. administration of MCT:FO on the recovery of cardiac function after ischemia in control and n-3-depleted rats. Results were compared with those obtained either with a control preparation, where FO was replaced by triolein (MCT:OO), or with saline. Saline (1 ml) or lipid preparation (also 1 ml) was injected as a bolus via the left saphenous vein. After 60 min the heart was …