Search results for " malattie."

showing 10 items of 1941 documents

Introducing a core curriculum for respiratory sleep practitioners

2015

Abstract: The background and purpose of the HERMES (Harmonising Education in Respiratory Medicine for European Specialists) initiative has been discussed at length in previous articles [1–3]. This article aims to provide more detailed and specific insight into the process and methodology of the Sleep HERMES Task Force in developing a core curriculum in respiratory sleep medicine.

Pulmonary and Respiratory MedicineMedical educationmedicine.medical_specialty5MEDICINEDISORDERSTask forceProcess (engineering)ReviewsHERMESSettore MED/10 - Malattie Dell'Apparato RespiratorioACCREDITATIONCore curriculumSleep medicineRespiratory Medicine18medicineHuman medicineSleep (system call)PsychologyAccreditationBreathe
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Bronchial responsiveness and airway inflammation in trained subjects [9]

2008

Pulmonary and Respiratory MedicineNeutrophilSputumBronchial HyperreactivityBronchitiSettore MED/10 - Malattie Dell'Apparato RespiratorioAsthmaHumanExercise Therapy
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The Importance of Phenotyping Bronchiectasis.

2016

Bronchiectasis is considered to be one of the most heterogeneous respiratory diseases due to both multiple etiological conditions and variable clinical manifestations. This huge heterogeneity is one of the main reasons for disease complexity, and thus, there is a need to identify clinical phenotypes which have specific therapeutic and follow-up indications as in other respiratory diseases [i.e. chronic obstructive pulmonary disease (COPD) or asthma]. Unfortunately, identifying phenotypes of bronchiectasis is not an easy task, and so far, attempts to link aetiology to clinical severity have failed.

Pulmonary and Respiratory MedicinePathologymedicine.medical_specialtyBronchiectasisbusiness.industrySettore MED/10 - Malattie Dell'Apparato Respiratoriomedicine.diseaseBronchiectasis03 medical and health sciences0302 clinical medicine030228 respiratory systemmedicineHumans030212 general & internal medicinebusinessRespiration; international review of thoracic diseases
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Clinical implications of airway hyper-responsiveness in COPD

2006

COPD represents one of the leading causes of mortality in the general population. This study aimed at evaluating the relationship between airway hyperresponsiveness (AHR) and COPD and its relevance for clinical practice. We performed a MEDLINE search that yielded a total of 1919 articles. Eligible studies were defined as articles that addressed specific aspects of AHR in COPD, such as prevalence, pathogenesis, or prognosis. AHR appears to be present in at least one out of two individuals with COPD. The occurrence of AHR in COPD is influenced by multiple mechanisms, among which impairment of factors that oppose airway narrowing plays an important role. The main determinants of AHR are reduct…

Pulmonary and Respiratory MedicinePathologymedicine.medical_specialtymedicine.medical_treatmentMEDLINEPopulationReviewsSettore MED/10 - Malattie Dell'Apparato RespiratorioBioinformaticsBronchial Provocation TestsPathogenesisDiagnosis DifferentialMedical Subject HeadingsPulmonary Disease Chronic ObstructivePredictive Value of TestsmedicineRespiratory HypersensitivityCOPDHumansairway smooth muscle aging bronchial obstructioneducationLungAsthmaCOPDeducation.field_of_studyLungbusiness.industryHealth Policyairway hyperresponsivenessSmokingPublic Health Environmental and Occupational HealthGeneral Medicinerespiratory systemmedicine.diseasePrognosisAsthmarespiratory tract diseasesbronchial hyperreactivitymedicine.anatomical_structurePredictive value of testsSmoking cessationbusinessAirwayInternational Journal of Chronic Obstructive Pulmonary Disease
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An Official American Thoracic Society Workshop Report: Evaluation and Management of Asthma in the Elderly.

2016

Asthma in the elderly (>65 yr old) is common and associated with higher morbidity and mortality than asthma in younger patients. The poor outcomes in this group are due, in part, to underdiagnosis and undertreatment. There are a variety of factors related to aging itself that affect the presentation of asthma in the elderly and influence diagnosis and management. Structural changes in the aging lung superimposed on structural changes due to asthma itself can worsen the disease and physiologic function. Changes in the aging immune system influence the cellular composition and function in asthmatic airways. These processes and differences from younger individuals with asthma are not well u…

Pulmonary and Respiratory MedicinePediatricsmedicine.medical_specialtyAgingImmunosenescenceaging; immunosenescence; lung function; phenotype; reactive airways diseaseDiseaseComorbiditySettore MED/10 - Malattie Dell'Apparato RespiratorioAffect (psychology)Diagnosis Differential03 medical and health sciencesPulmonary Disease Chronic Obstructive0302 clinical medicineimmune system diseasesreactive airways diseasemedicineHumans030212 general & internal medicineDisease management (health)LungSocieties MedicalAsthmaAgedAmerican Thoracic Society DocumentsLungbusiness.industryDisease Managementlung functionImmunosenescencemedicine.diseaseComorbidityAsthmaUnited Statesrespiratory tract diseasesmedicine.anatomical_structurePhenotype030228 respiratory systemPhysical therapyAge of onsetbusinessBiomarkersAnnals of the American Thoracic Society
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Should atopy be assessed in elderly patients with respiratory symptoms suggestive of asthma?

2010

Aging is associated with modifications of the immune system and this could contribute to a reduced prevalence of allergic disease in the elderly. Atopy has rarely been considered in the clinical assessment of the geriatric respiratory patient. This article is a review of the available literature assessing the impact of age on atopy in the asthmatic patient. In the majority of papers, we found a lower prevalence of atopy in the most advanced ages, both in healthy subjects and in individuals affected by allergic respiratory diseases. No large, longitudinal studies performed in the general population have been conducted to confirm this observation. Although available data seem to favor the dec…

Pulmonary and Respiratory MedicinePediatricsmedicine.medical_specialtyAgingPopulationDiseaseSettore MED/10 - Malattie Dell'Apparato RespiratorioImmunoglobulin Emedicine.disease_causeAtopyAllergic sensitizationAllergenmedicineHypersensitivityPrevalenceImmunology and AllergyHumansaging allergy asthmaRespiratory systemeducationAsthmaAgedAged 80 and overeducation.field_of_studybiologybusiness.industryPublic Health Environmental and Occupational HealthAge FactorsAllergensmedicine.diseasePrognosisAsthmaImmunologybiology.proteinbusinessExpert review of respiratory medicine
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Role of menopause and hormone replacement therapy in sleep-disordered breathing

2020

There are suggestions that the loss of female sex hormones following menopause is critical for the development or progression of sleep-disordered breathing (SDB). We conducted a review of the literature on the role of menopause and hormone replacement therapy (HRT) in SDB risk. There is an increase in SDB during the menopausal transition period, but data on an effect beyond that of increasing age and changes in body habitus are weak or absent. Early community-based, observational studies reported a protective effect by HRT on SDB prevalence, but this could possibly be explained as a healthy user effect. Interventional studies of the effect of HRT on SDB are sparse, with only a few randomize…

Pulmonary and Respiratory MedicinePediatricsmedicine.medical_specialtymedicine.drug_classSettore MED/10 - Malattie Dell'Apparato Respiratorio03 medical and health sciencesSleep Apnea Syndromes0302 clinical medicineWomanPhysiology (medical)mental disordersPrevalenceHumansMedicineObesitycardiovascular diseasesSleep-disordered breathingbusiness.industrymedicine.diseaseEstrogenObstructive sleep apneaObesitynervous system diseasesrespiratory tract diseasesObstructive sleep apneaMenopauseMetabolismHormone replacement therapy030228 respiratory systemNeurologyEstrogenTransgender hormone therapySleep disordered breathingFemaleObservational studysense organsNeurology (clinical)Menopausebusiness030217 neurology & neurosurgeryHormoneSleep Medicine Reviews
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Serum Surfactant Protein D as a Marker of Asthma Severity

2016

Pulmonary and Respiratory MedicinePulmonary Surfactant-Associated Protein Abusiness.industryAsthma severitySurfactant protein DBiomarkerSettore MED/10 - Malattie Dell'Apparato Respiratoriomedicine.diseasePulmonary Surfactant-Associated Protein DCritical Care and Intensive Care MedicineAsthma03 medical and health sciences0302 clinical medicine030228 respiratory systemImmunologyMedicineHumans030212 general & internal medicinePulmonary Surfactant-Associated Protein DbusinessCardiology and Cardiovascular MedicineBiomarkersAsthmaPulmonary Surfactant-Associated Protein AHuman
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Why small particle fixed dose triple therapy? An excursus from COPD pathology to pharmacological treatment evolution

2022

Although bronchodilators are the cornerstone in chronic obstructive pulmonary disease (COPD) therapy, the treatment with a single-agent bronchodilator may not provide adequate symptoms control in COPD. The combination of drugs with different mechanisms of action may be more effective in inducing bronchodilation and preventing exacerbations, with a lower risk of side-effects in comparison with the increase of the dose of a single molecule. Several studies comparing the triple therapy with the association of long-acting ß2 agonist (LABA)/inhaled corticosteroid (ICS) or long-acting muscarinic antagonist (LAMA)/LABA reported improvement of lung function and quality of life. A significant reduc…

Pulmonary and Respiratory MedicineRC705-779ReviewMuscarinic AntagonistsSettore MED/10 - Malattie Dell'Apparato RespiratorioCOPD inhaled extrafine formulation triple therapyinhaled extrafine formulationBronchodilator AgentsDrug CombinationsPulmonary Disease Chronic ObstructiveDiseases of the respiratory systemtriple therapyFormoterol FumarateAdministration InhalationQuality of LifeCOPDHumansDrug Therapy CombinationPharmacology (medical)Adrenergic beta-2 Receptor AgonistsTherapeutic Advances in Respiratory Disease
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Mild obstructive sleep apnoea: clinical relevance and approaches to management

2015

Summary Obstructive sleep apnoea is highly prevalent in the general population worldwide, especially in its mild form. Clinical manifestations correlate poorly with disease severity measured by the apnoea–hypopnoea index (AHI), which complicates diagnosis. Full polysomnography might be more appropriate to assess suspected mild cases because limited ambulatory diagnostic systems are least accurate in mild disease. Treatment options in mild obstructive sleep apnoea include continuous positive airway pressure (CPAP) and oral appliance therapy, in addition to positional therapy and weight reduction when appropriate. The superior efficacy of CPAP in reducing AHI is offset by greater tolerance of…

Pulmonary and Respiratory MedicineRespiratory Therapymedicine.medical_specialtymedicine.medical_treatmentOral appliancePopulationPolysomnographySettore MED/10 - Malattie Dell'Apparato RespiratorioPatient Positioning03 medical and health sciences0302 clinical medicinestomatognathic systemmedicineHumansClinical significanceContinuous positive airway pressureDisease management (health)Intensive care medicineeducationSleep Apnea Obstructiveeducation.field_of_studyContinuous Positive Airway Pressuremedicine.diagnostic_testbusiness.industryDisease ManagementSleep apneamedicine.diseasenervous system diseasesrespiratory tract diseases030228 respiratory systemAmbulatoryPhysical therapybusiness030217 neurology & neurosurgery
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