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RESEARCH PRODUCT
Mild obstructive sleep apnoea: clinical relevance and approaches to management
Maria R. BonsignorePatrick LevyWalter T. McnicholasSilke Ryansubject
Pulmonary and Respiratory MedicineRespiratory Therapymedicine.medical_specialtymedicine.medical_treatmentOral appliancePopulationPolysomnographySettore MED/10 - Malattie Dell'Apparato RespiratorioPatient Positioning03 medical and health sciences0302 clinical medicinestomatognathic systemmedicineHumansClinical significanceContinuous positive airway pressureDisease management (health)Intensive care medicineeducationSleep Apnea Obstructiveeducation.field_of_studyContinuous Positive Airway Pressuremedicine.diagnostic_testbusiness.industryDisease ManagementSleep apneamedicine.diseasenervous system diseasesrespiratory tract diseases030228 respiratory systemAmbulatoryPhysical therapybusiness030217 neurology & neurosurgerydescription
Summary Obstructive sleep apnoea is highly prevalent in the general population worldwide, especially in its mild form. Clinical manifestations correlate poorly with disease severity measured by the apnoea–hypopnoea index (AHI), which complicates diagnosis. Full polysomnography might be more appropriate to assess suspected mild cases because limited ambulatory diagnostic systems are least accurate in mild disease. Treatment options in mild obstructive sleep apnoea include continuous positive airway pressure (CPAP) and oral appliance therapy, in addition to positional therapy and weight reduction when appropriate. The superior efficacy of CPAP in reducing AHI is offset by greater tolerance of oral appliances, especially in mild disease. Although severe obstructive sleep apnoea is associated with adverse health consequences, including cardiometabolic comorbidities, the association with mild disease is unclear, and reports differ regarding the clinical relevance of mild obstructive sleep apnoea. Improved diagnostic techniques and evidence-based approaches to management in mild obstructive sleep apnoea require further research.
year | journal | country | edition | language |
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2015-12-14 |