Search results for " mani"
showing 10 items of 623 documents
Groups acting freely on Calabi-Yau threefolds embedded in a product of del Pezzo surfaces
2011
In this paper, we investigate quotients of Calabi-Yau manifolds $Y$ embedded in Fano varieties $X$, which are products of two del Pezzo surfaces — with respect to groups $G$ that act freely on $Y$. In particular, we revisit some known examples and we obtain some new Calabi-Yau varieties with small Hodge numbers. The groups $G$ are subgroups of the automorphism groups of $X$, which is described in terms of the automorphism group of the two del Pezzo surfaces.
Essential versus accessory aspects of cell death: recommendations of the NCCD 2015
2015
Cells exposed to extreme physicochemical or mechanical stimuli die in an uncontrollable manner, as a result of their immediate structural breakdown. Such an unavoidable variant of cellular demise is generally referred to as ?accidental cell death' (ACD). In most settings, however, cell death is initiated by a genetically encoded apparatus, correlating with the fact that its course can be altered by pharmacologic or genetic interventions. "Regulated cell death" (RCD) can occur as part of physiologic programs or can be activated once adaptive responses to perturbations of the extracellular or intracellular microenvironment fail. The biochemical phenomena that accompany RCD may be harnessed to…
Effectiveness of classic physical therapy proposals for chronic non-specific low back pain: a literature review
2018
Introduction Chronic low back pain is a pathological process that compromises the functionality and quality of life worldwide. The objective of the study was to evaluate the effectiveness of classical physiotherapy in the management of non-specific chronic low back pain. Methods A literature search in English electronic databases was performed from November to December of 2015. Only those studies addressing chronic non-specific low back pain by manual therapy and different types of exercises methods were included, and those, which combined acute or subacute pain with systematic reviews and clinical practice guidelines, were excluded. Studies involving cognitive-behavioral approaches were al…
Atypical Antipsychotics in the Treatment of Acute Bipolar Depression with Mixed Features: A Systematic Review and Exploratory Meta-Analysis of Placeb…
2016
Evidence supporting the use of second generation antipsychotics (SGAs) in the treatment of acute depression with mixed features (MFs) associated with bipolar disorder (BD) is scarce and equivocal. Therefore, we conducted a systematic review and preliminary meta-analysis investigating SGAs in the treatment of acute BD depression with MFs. Two authors independently searched major electronic databases from 1990 until September 2015 for randomized (placebo-) controlled trials (RCTs) or open-label clinical trials investigating the efficacy of SGAs in the treatment of acute bipolar depression with MFs. A random-effect meta-analysis calculating the standardized mean difference (SMD) between SGA an…
Holistic and unified approach to facilitate graphical data visualization and statistical predictive modelling for diseases at the microorganism level
2015
Borrelia species are predominantly responsible for the most common form of Tick-borne diseases (TBD) which is Lyme borreliosis (LB). Episodes of Lyme arthritis (LA) is a hallmark symptom of LB patients. LA is an atypical form of reactive arthritis (ReA) that is a sub-type of Spondyloarthritis (SpA). Coinfections such as Ehrlichia chaffeensis accompany primary Borrelia species during the later stages of LB infection to induce severe symptoms. Currently, there is no holistic approach that would unify different TBD pathogens into independent and multiple TBD infection (MTBDI) combination categories to facilitate graphical and statistical analysis between any two patients groups. The chronic ma…
Calibrations and isoperimetric profiles
2007
We equip many noncompact nonsimply connected surfaces with smooth Riemannian metrics whose isoperimetric profile is smooth, a highly nongeneric property. The computation of the profile is based on a calibration argument, a rearrangement argument, the Bol-Fiala curvature dependent inequality, together with new results on the profile of surfaces of revolution and some hardware know-how.
Dipolar Rings of Microscopic Ellipsoids: Magnetic Manipulation and Cell Entrapment
2016
We study the formation and dynamics of dipolar rings composed by microscopic ferromagnetic ellipsoids, which self-assemble in water by switching the direction of the applied field. We show how to manipulate these fragile structures and control their shape via application of external static and oscillating magnetic fields. We introduce a theoretical framework which describes the ring deformation under an applied field, allowing to understand the underlying physical mechanism. Our microscopic rings are finally used to capture, entrap and later release a biological cell via magnetic command, i.e. performing a simple operation which can be implemented in other microfluidic devices which make us…
A Multicentric Randomized Trial to Evaluate the ROle of Uterine MANipulator on Laparoscopic/Robotic HYsterectomy for the Treatment of Early-Stage End…
2021
ObjectiveThis prospective randomized trial aimed to assess the impact of the uterine manipulator in terms of lymph vascular space invasion (LVSI) in patients undergoing minimally invasive staging for early-stage endometrial cancer.MethodsIn this multicentric randomized trial, enrolled patients were randomly allocated in two groups according to the no use (arm A) or the use (arm B) of the uterine manipulator. Inclusion criteria were G1-G2 early-stage endometrial cancer at preoperative evaluation. The variables collected included baseline demographic characteristics, perioperative data, final pathology report, adjuvant treatment, and follow-up.ResultsIn the study, 154 patients (76 in arm A an…
Oral Manifestations of Wolf-Hirschhorn Syndrome: Genotype-Phenotype Correlation Analysis
2020
Background: Wolf-Hirschhorn syndrome (WHS) is a rare disease caused by deletion in the distal moiety of the short arm of chromosome 4. The objectives of this study were to report the most representative oral findings of WHS, relate them with other clinical characteristics of the disease, and establish possible phenotype-genotype correlation. Methods: The study was conducted at 6 reference centers distributed throughout Spain during 2018&ndash
Il Castello Maniace di Siracusa. Stereotomia e tecniche costruttive nell’architettura del Mediterraneo
2011
L’enigma del castello Maniace di Siracusa, realizzato nella prima metà del XIII secolo per volontà dell’imperatore Federico II, ruota intorno all’immensa sala colonnare, alla sua funzione e ai criteri costruttivi adottati per edificarla. L’autrice ha avuto l’opportunità di studiare capillarmente la fabbrica, assumendo una conoscenza materica diretta, grazie alla lunga frequentazione, resa possibile dal cantiere di restauro che ha recentemente restituito il “monumento” alla fruizione pubblica. Queste informazioni sono state utilizzate per verificare le diverse letture e ipotesi sinora formulate e l’indagine procede a partire dalla densa serie di quesiti inevasi. Di fronte a una architettura …