Search results for " migration."

Heat shock factor 2 is a stress-responsive mediator of neuronal migration defects in models of fetal alcohol syndrome

2014

Fetal alcohol spectrum disorder (FASD) is a frequent cause of mental retardation. However, the molecular mechanisms underlying brain development defects induced by maternal alcohol consumption during pregnancy are unclear. We used normal and Hsf2-deficient mice and cell systems to uncover a pivotal role for heat shock factor 2 (HSF2) in radial neuronal migration defects in the cortex, a hallmark of fetal alcohol exposure. Upon fetal alcohol exposure, HSF2 is essential for the triggering of HSF1 activation, which is accompanied by distinctive post-translational modifications, and HSF2 steers the formation of atypical alcohol-specific HSF1–HSF2 heterocomplexes. This perturbs the in vivo bindi…

Contribution à la connaissance de l'implantation Burgonde en Gaule au Ve siècle : à propos de découvertes récentes de fibules zoomorphes

2011

The recent discovery of three horse shaped fibulae – a pair with a cavalryman from Ecrille in the Jura and a fibula from the La Chambre sector in Savoie as well as a bird shaped fibula from Charpey in the Drome, all dating from the second half of the 5th century or around 500 AD, provide valuable references in the context of the Burgundian settlement in the Centre-East and the South-East of Gaul. The map is still incomplete notably for the area to the south of Lyon, precisely where La Chambre and Charpey are located. Relating to the Ecrille discovery, it provides new information in relation to this defended site underlining its importance.

Migracje absolwentów szkół wyższych a kształtowanie się kapitału ludzkiego w województwie opolskim

2019

Województwo opolskie to region silnie zdeterminowany demograficznie szczególnie procesami migracyjnymi o różnorodnych implikacjach społecznych i ekonomicznych. Intensywne migracje obok dywersyfikacji etnicznej ludności składają się na specyfikę regionu i powodują, że problemy związane z ruchem wędrówkowym nabierają istotnego znaczenia w kontekście jego dalszego rozwoju. Kapitał ludzki zarówno w wymiarze ilościowym, jak i jakościowym stanowi kluczowy endogeniczny czynnik rozwoju każdego obszaru decydujący o jego potencjale rozwojowym, dlatego też stały odpływ dobrze wykwalifikowanej kadry – absolwentów szkół wyższych za granicę, który obserwujemy nie tylko w regionie, ale również w całym kra…

(Un)framing Lampedusa: Regimes of Visibility and the Politics of Affect in Italian Media Representations

2017

The 3rd of October 2013 more than 300 migrants died after a boat sank off the coasts of Lampedusa. This probably was the most dramatic shipwreck ever happened in the Mediterranean, and certainly the one which attracted the most media attention in Italy and elsewhere. Since at least 1992 the Mediterranean has become the unstable ground where the dominant policies of regulated mobility and discontinuous surveillance are continuously challenged by bodies which struggle for their fundamental right to move. This conflict between global regimes of disciplined mobility (Philo 2014) and singular forms of embodied resistance (Agamben 1990) involves also the field of representation and its forcible e…

Transcontinental 2200 km migration of a Nathusius’ pipistrelle (Pipistrellus nathusii) across Europe

2021

A male Pipistrellus nathusii ringed in Pape Natural Park (S Latvia) in August 2015 was recovered recently dead in Pitillas’ Lagoon Natural Reserve (N Spain) in March 2017. At 2224 km in SSW direction, this is the first documented bat migration between these countries and worldwide the longest migration record of a bat. We also report other observations of this species in autumn in Northern Spain, suggesting that the Iberian Peninsula may be an important wintering area for Nathusius’ pipistrelles. Conservation measures should be agreed on by countries along the migration routes to improve the protection of this species. nonPeerReviewed

Fructose 2,6-bisphosphate as a signal for changing from sugar to lipid oxidation during flight in locusts

1986

AbstractFlight in locusts is initially powered mainly by carbohydrate but if flight is to be sustained, as in migration, the animals have to utilize fat as the predominant fuel. The molecular basis of this metabolic switch has not been identified. Fructose 2,6-bisphosphate is a potent activator of 6-phosphofructokinase (EC 2.7.1.11) purified from locust flight muscle. After the first few minutes of flight in the locust the concentration of fructose 2,6-bisphosphate in the flight muscle falls dramatically, which should lead to a decrease in the activity of 6-phosphofructokinase as part of the mechanism to conserve carbohydrate during prolonged flight.

Notch and Numb are required for normal migration of peripheral glia in Drosophila

2006

Abstract A prominent feature of glial cells is their ability to migrate along axons to finally wrap and insulate them. In the embryonic Drosophila PNS, most glial cells are born in the CNS and have to migrate to reach their final destinations. To understand how migration of the peripheral glia is regulated, we have conducted a genetic screen looking for mutants that disrupt the normal glial pattern. Here we present an analysis of two of these mutants: Notch and numb. Complete loss of Notch function leads to an increase in the number of glial cells. Embryos hemizygous for the weak NotchB-8X allele display an irregular migration phenotype and mutant glial cells show an increased formation of …

Synthesis and biological evaluation of new imidazo[2,1-b][1,3,4]thiadiazole derivatives: as anticancer and antibiofilm agents, and preclinical invest…

2020

Recensione di La questione mediterranea

2019

Review of the book La questione mediterranea, by Ian Chambers and Marta Cariello, where the mediterranean is like a fluid archive, which is never intended as a collector of dead objects, but unlike traces, removed but never dormant, consisting of cultural practices.

Translating migration: digital narratives, (anti) museums in action and documentaries

2016

This article investigates the modalities through which the migrant crisis is portrayed in the creative artistic sector that, in turn, has accelerated the spread of political participatory and activist movements in the areas of subtitling and amateur translation. This innovative trend involving the sphere of translation has been acting as an important stimulus for the international mushrooming of artistic creativities on public spaces and digital platforms, but also for the formation of new views on translation and interpretation as actively contributing to the reframing of the political aspects of the migrant crisis. Such a counter wave of artistic productions has emerged within a Europe th…