Search results for " mobility"
showing 10 items of 577 documents
Cycloamphilectenes, a new type of potent marine diterpenes: inhibition of nitric oxide production in murine macrophages.
2003
The inhibitory effect of a series of 6 cycloamphilectenes, novel marine diterpenes based on amphilectene skeletons and isolated from the Vanuatu sponge Axinella sp., on NO, PGE(2) and TNFalpha production in murine peritoneal macrophages was studied. These compounds reduced potently nitric oxide production in a concentration-dependent manner with IC(50) values in the submicromolar range (0.1-4.3 microM). Studies on intact cells and Western blot analysis showed that the more potent cycloamphilectenes reduced the expression of inducible nitric oxide synthase without affecting cyclo-oxygenase-2 expression. Among them cycloamphilectene 2, the unique compound bearing an exocyclic methylene group,…
Peptidases specific for proline-containing peptides and their unusual peptide-dependent regulation in Oenococcus oeni
2009
International audience; Growth of the lactic acid bacterium (LAB) Oenococcus oeni, which is involved in malolactic fermentation during the winemaking process, is stimulated by peptides originating from yeast. In this study, we investigated the impact of peptides on O. oeni growth, peptidase activity and the expression of genes encoding the studied peptidases. Low levels of PepN activity and very high levels of PepI activity were observed in O. oeni, whereas levels of PepX activity were intermediate. The level of biosynthesis of these O. oeni peptidases was shown to depend on peptides present in the culture medium. These results were confirmed by transcriptional analyses of putative pep gene…
Dislocation mobility study of heavy ion induced track damage in LiF crystals
2008
Track damage created in LiF crystals by swift U, Kr, Xe and Ni ions with a specific energy of 11.1 MeV/u was studied using dislocation mobility measurements, track etching, SEM, AFM and optical microscopy. The results demonstrate continuity of etching of U tracks while discontinuities of etching are observed in the case of Xe ions. The relationship between the track structure and dislocation mobility in irradiated crystals is discussed. The dislocation mobility technique can serve as a highly sensitive method for track core damage studies.
A mobility analysis of the occupational status of the graduates of the University of Palermo in an economic crisis context
2019
In such a global economic crisis context, our aims are describing the mobility of the Palermitan graduates in the labour market, identifying the variables that influence most their occupational status and finally outlining a transition probability structure among the states: Work, Search for a Job, Study, Other. The availability of a large amount of longitudinal data provided by the surveys carried out by STELLA (Statistics about Graduates and Labour Market) allowed us to analyze the mobility of the graduates of the University of Palermo among the different occupational states in three different times. We analyze data coming from a disproportionate stratified sample of graduates in 2009, in…
Association of low-penetrance alleles with male breast cancer risk and clinicopathological characteristics: results from a multicenter study in Italy
2013
It is well-known that male breast cancer (MBC) susceptibility is mainly due to high-penetrance BRCA1/2 mutations. Here, we investigated whether common low-penetrance breast cancer (BC) susceptibility alleles may influence MBC risk in Italian population and whether variant alleles may be associated with specific clinicopathological features of MBCs. In the frame of the Italian Multicenter Study on MBC, we genotyped 413 MBCs and 745 age-matched male controls at 9 SNPs annotating known BC susceptibility loci. By multivariate logistic regression models, we found a significant increased MBC risk for 3 SNPs, in particular, with codominant models, for rs2046210/ESR1 (OR = 1.71; 95 % CI: 1.43–2.05;…
Common Breast Cancer Susceptibility Alleles and the Risk of Breast Cancer for BRCA1 and BRCA2 Mutation Carriers: Implications for Risk Prediction
2010
Abstract The known breast cancer susceptibility polymorphisms in FGFR2, TNRC9/TOX3, MAP3K1, LSP1, and 2q35 confer increased risks of breast cancer for BRCA1 or BRCA2 mutation carriers. We evaluated the associations of 3 additional single nucleotide polymorphisms (SNPs), rs4973768 in SLC4A7/NEK10, rs6504950 in STXBP4/COX11, and rs10941679 at 5p12, and reanalyzed the previous associations using additional carriers in a sample of 12,525 BRCA1 and 7,409 BRCA2 carriers. Additionally, we investigated potential interactions between SNPs and assessed the implications for risk prediction. The minor alleles of rs4973768 and rs10941679 were associated with increased breast cancer risk for BRCA2 carrie…
Determination of charge carrier mobility of hole transporting polytriarylamine-based diodes
2010
Hole transport properties of three different side chain poly(triarylamines) have been determined by means of the analysis of steady-state current-voltage characteristics using co-planar diode structures. The interpretation is based on space-charge limited models with field-dependent mobility. Mobilities between ~ 10- 8 and 10- 6 cm2 V- 1 s- 1 are obtained. The highest mobility is achieved for poly(tetraphenylbenzidine) devices and the lowest for poly(triphenylamine) devices. Electron-rich methoxy substituents increase the mobility of poly(triphenylamine)s. A comparison of the mobility values with those obtained using organic field-effect transistors is also given. © 2009 Elsevier B.V. All r…
The labour market consequences of self-employment spells:European evidence
2008
Hundreds of thousands of Europeans enter self-employment each year, but because self-employment spells are typically brief, many of them exit soon after entry. We examine how those who return to paid-employment fare on the labour market using the European Community Household Panel (ECHP). Like earlier evidence for the US, ours indicate that, in general, brief spells of self-employment do not increase average hourly earnings upon return to paid-employment. For highly educated men, an additional year of self-employment actually decreases their earnings by 4-5% relative to a year of continued wage employment. We also find that brief spells of self-employment are associated with increased proba…
Proyecto migratorio y trayectorias laborales de cuidadoras latinoamericanas: efectos de la Gran Recesión. Un estudio cualitativo en el Área Metropoli…
2021
Este texto aborda el proyecto migratorio y las trayectorias laborales de mujeres latinoamericanas que trabajan como cuidadoras en el ámbito doméstico en el Área Metropolitana de Valencia. A partir del uso de una metodología cualitativa se llega a varias conclusiones: existe una explicación multicausal de los proyectos migratorios, predominando los de carácter económico/laboral, y, en segundo lugar, sus trayectorias laborales se caracterizan por el mantenimiento en las mismas ocupaciones con ligeros cambios, o con modificaciones en sectores muy concretos. Además, la Gran Recesión ha afectado de manera negativa aquellas que habían visto levemente mejoradas sus posiciones en el mercado laboral…
L'inflation scolaire : Les désillusions de la méritocratie
2006
06001 - Il existe une édition japonaise, parue en décembre 2007, avec préface inédite.; « Les études, plus on fait, mieux on se porte ». Voici ce qu'on pourrait lire dans le Dictionnaire des idées reçues contemporaines à l'entrée « Ecole ». Cette conviction partagée est-elle encore pertinente ? On peut en douter. Pour les individus d'abord, dont le mérite ne se trouve pas nécessairement mieux reconnu, ni l'hérédité sociale mieux conjurée, parce qu'ils seront restés plus longtemps sur les bancs de l'école. Pour la société ensuite, car la distribution des places et des emplois ne se fait pas forcément de manière plus pertinente quand elle s'appuie sur les seuls diplômes délivrés par l'école. …