Search results for " model"

showing 10 items of 16868 documents

Sex-allocation conflict and sexual selection throughout the lifespan of eusocial colonies.

2018

AbstractModels of sex allocation conflict are central to evolutionary biology but have mostly assumed static decisions, where resource allocation strategies are constant over colony lifespan. Here, we develop a model to study how the evolution of dynamic resource allocation strategies is affected by the queen-worker conflict in annual eusocial insects. We demonstrate that the time of dispersal of sexuals affects the sex allocation ratio through sexual selection on males. Furthermore, our model provides three predictions that depart from established results of classic static allocation models. First, we find that the queen wins the sex allocation conflict, while the workers determine the max…

0106 biological sciences0301 basic medicineConflictconflictmedia_common.quotation_subjectLongevitylife-history strategyresursointiBiology010603 evolutionary biology01 natural sciencesModels BiologicalLife history theory03 medical and health sciencesGeneticsAnimalsEcology Evolution Behavior and SystematicsSex allocationmedia_commonsex allocationsocial insectsoptimal resource allocationLongevityOriginal ArticlesMating Preference AnimalSex Determination ProcessesyhteiskuntahyönteisetEusocialityHymenoptera030104 developmental biologyAnimals; Hymenoptera/growth & development; Hymenoptera/physiology; Longevity; Mating Preference Animal; Models Biological; Sex Determination Processes; Conflict; life-history strategy; optimal resource allocation; sex allocation; social insectssukupuolivalintaSexual selectionResource allocationBiological dispersalDemographic economicsOriginal Articlelife‐history strategyGeneral Agricultural and Biological SciencesaitososiaalisuusDynamic resourceEvolution; international journal of organic evolution
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Parallel diversifications of Cremastosperma and mosannona (annonaceae), tropical rainforest trees tracking neogene upheaval of South America

2018

Much of the immense present day biological diversity of Neotropical rainforests originated from the Miocene onwards, a period of geological and ecological upheaval in South America. We assess the impact of the Andean orogeny, drainage of Lake Pebas and closure of the Panama isthmus on two clades of tropical trees ( Cremastosperma , ca 31 spp.; and Mosannona , ca 14 spp.; both Annonaceae). Phylogenetic inference revealed similar patterns of geographically restricted clades and molecular dating showed diversifications in the different areas occurred in parallel, with timing consistent with Andean vicariance and Central American geodispersal. Ecological niche modelling approaches show phyloge…

0106 biological sciences0301 basic medicineDIVERSITY01 natural sciencesNiche modellingDISPERSALlcsh:ScienceMultidisciplinarybiologyEcologyAmazon rainforest70Biology (Whole Organism)ANDEAN UPLIFTPE&RCBiosystematieknicheGeographyGeodispersalinternationalISTHMUSMolecular datingCLADESPebas systemResearch Article1001Neotropics201004PHYLOGENY RECONSTRUCTIONRainforest010603 evolutionary biologymodelling03 medical and health sciencesHISTORICAL BIOGEOGRAPHYDIVERGENCEVicarianceSPECIATIONLaboratorium voor NematologieEcological nicheAndean orogenyAndean orogenyBiology and Life Sciencesbiology.organism_classificationEVOLUTION030104 developmental biologyMosannonaPanama isthmusBiosystematicslcsh:QEPSLaboratory of NematologyTropical rainforestRoyal Society Open Science
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On the thermodynamic origin of metabolic scaling

2018

The origin and shape of metabolic scaling has been controversial since Kleiber found that basal metabolic rate of animals seemed to vary as a power law of their body mass with exponent 3/4, instead of 2/3, as a surface-to-volume argument predicts. The universality of exponent 3/4 -claimed in terms of the fractal properties of the nutrient network- has recently been challenged according to empirical evidence that observed a wealth of robust exponents deviating from 3/4. Here we present a conceptually simple thermodynamic framework, where the dependence of metabolic rate with body mass emerges from a trade-off between the energy dissipated as heat and the energy efficiently used by the organi…

0106 biological sciences0301 basic medicineFOS: Physical scienceslcsh:Medicine92B05010603 evolutionary biology01 natural sciencesPower lawArticle03 medical and health sciencesFractalPhysics - Biological PhysicsStatistical physicslcsh:ScienceQuantitative Biology - Populations and EvolutionAdditive modelScalingMathematicsMultidisciplinarylcsh:RPopulations and Evolution (q-bio.PE)Universality (dynamical systems)030104 developmental biologyBiological Physics (physics.bio-ph)13. Climate actionFOS: Biological sciencesEctothermBasal metabolic rateExponentlcsh:QScientific Reports
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A hierarchical Bayesian Beta regression approach to study the effects of geographical genetic structure and spatial autocorrelation on species distri…

2019

Global climate change (GCC) may be causing distribution range shifts in many organisms worldwide. Multiple efforts are currently focused on the development of models to better predict distribution range shifts due to GCC. We addressed this issue by including intraspecific genetic structure and spatial autocorrelation (SAC) of data in distribution range models. Both factors reflect the joint effect of ecoevolutionary processes on the geographical heterogeneity of populations. We used a collection of 301 georeferenced accessions of the annual plant Arabidopsis thaliana in its Iberian Peninsula range, where the species shows strong geographical genetic structure. We developed spatial and nonsp…

0106 biological sciences0301 basic medicineHierarchical Bayesian modelsArabidopsis thalianaRange (biology)Bayesian probabilitySpecies distributionArabidopsisGenetic admixtureBiologyResidual010603 evolutionary biology01 natural sciences03 medical and health sciencesAfrica NorthernStatisticsGeneticsSpatial analysisEcology Evolution Behavior and SystematicsSpatial AnalysisPortugalPlant DispersalGenetic heterogeneityGlobal climate changePhylogeographyGenetics Population030104 developmental biologySpainGenetic structureGeographic genetic structureMaxentPeptidesSpatial autocorrelationBiotechnology
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Daphnia invest in sexual reproduction when its relative costs are reduced

2018

The timing of sex in facultatively sexual organisms is critical to fitness, due to the differing demographic consequences of sexual versus asexual reproduction. In addition to the costs of sex itself, an association of sex with the production of dormant life stages also influences the optimal use of sex, especially in environments where resting eggs are essential to survive unfavourable conditions. Here we document population dynamics and the occurrence of sexual reproduction in natural populations of Daphnia magna across their growing season. The frequency of sexually reproducing females and males increased with population density and with decreasing asexual clutch sizes. The frequency of…

0106 biological sciences0301 basic medicineLIFE-HISTORYsexual reproductioncost of sexAsexual reproductionCYCLICAL PARTHENOGENS01 natural sciencesDaphniaPopulation density2300 General Environmental Sciencetiming of sexLOCAL ADAPTATION2400 General Immunology and Microbiologypopulation dynamicsGeneral Environmental Scienceeducation.field_of_studybiologyINDUCTIONMIXED-EFFECTS MODELSGeneral MedicineCladocera1181 Ecology evolutionary biology590 Animals (Zoology)General Agricultural and Biological SciencesEvolutionPopulationDaphnia magna1100 General Agricultural and Biological SciencesPULEX010603 evolutionary biologyGeneral Biochemistry Genetics and Molecular Biology03 medical and health sciences10127 Institute of Evolutionary Biology and Environmental Studies1300 General Biochemistry Genetics and Molecular BiologyPopulation growtheducationpopulation densityLocal adaptationROTIFERSGeneral Immunology and Microbiologysuvullinen lisääntyminenreproduction (biology)biology.organism_classificationlisääntyminenpopulaatiodynamiikkaSexual reproduction030104 developmental biologyDaphniaMAGNADENSITYvesikirputta1181570 Life sciences; biologyDemography
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Open data and digital morphology

2017

International audience; Over the past two decades, the development of methods for visualizing and analysing specimens digitally, in three and even four dimensions, has transformed the study of living and fossil organisms. However, the initial promise that the widespread application of such methods would facilitate access to the underlying digital data has not been fully achieved. The underlying datasets for many published studies are not readily or freely available, introducing a barrier to verification and reproducibility, and the reuse of data. There is no current agreement or policy on the amount and type of data that should be made available alongside studies that use, and in some cases…

0106 biological sciences0301 basic medicineLife Sciences & Biomedicine - Other TopicsDYNAMICSComputer scienceDatasets as TopicReuse01 natural sciencesFOSSILSthree-dimensional modelsNaturvetenskapData CurationGeneral Environmental ScienceEcologypalaeontology[SDV.BID.EVO]Life Sciences [q-bio]/Biodiversity/Populations and Evolution [q-bio.PE]70General Medicine11 Medical And Health SciencesCCbiomechanics Keywords: digital dataOpen dataPerspectiveComputer data storage[SDU.STU.PG]Sciences of the Universe [physics]/Earth Sciences/PaleontologyGeneral Agricultural and Biological SciencesNatural SciencesLife Sciences & BiomedicineDatasets as Topic1001TISSUESphenotypeBest practiceDigital dataLibrary science25Environmental Sciences & Ecology010603 evolutionary biologyBiological Science DisciplinesGeneral Biochemistry Genetics and Molecular BiologyQA76functional analysisSet (abstract data type)03 medical and health sciencesPALEONTOLOGYBiologySubject Category: Morphology and biomechanics Subject Areas: evolutionvisualizationdigital dataEvolutionary BiologyScience & TechnologyTOMOGRAPHIC MICROSCOPYMorphology and BiomechanicsGeneral Immunology and Microbiologybusiness.industryResearchQHReproducibility of Resultscomputed tomographyPERFORMANCE06 Biological Sciences144Data scienceEVOLUTIONVisualization030104 developmental biologyVISUALIZATION07 Agricultural And Veterinary SciencesbusinessProceedings of the Royal Society B: Biological Sciences
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Phenological and intrinsic predictors of mite and haemacoccidian infection dynamics in a Mediterranean community of lizards

2021

Ectotherms are vulnerable to environmental changes and their parasites are biological health indicators. Thus, parasite load in ectotherms is expected to show a marked phenology. This study investigates temporal host–parasite dynamics in a lizard community in Eastern Spain during an entire annual activity period. The hosts investigated were Acanthodactylus erythrurus, Psammodromus algirus and Psammodromus edwardsianus, three lizard species coexisting in a mixed habitat of forests and dunes, providing a range of body sizes, ecological requirements and life history traits. Habitat and climate were considered as potential environmental predictors of parasite abundance, while size, body conditi…

0106 biological sciences0301 basic medicineMaleMite InfestationsRange (biology)ForestsParasitemia010603 evolutionary biology01 natural sciencesParasite loadParasite LoadLife history theory03 medical and health scienceshost–parasite dynamicsAbundance (ecology)Sandbiology.animalLacertidaeAnimalsEcological interactionsEcosystemAcanthodactylus erythrurusbiologyLizardEcologyCoccidiosisLizardsbiology.organism_classificationCoccidia030104 developmental biologyInfectious DiseasesSpainEctothermLinear ModelsAnimal Science and ZoologyParasitologyFemaleLacertidaeparasite phenologyResearch ArticleIberian PeninsulaParasitology
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Origin and distribution of desert ants across the Gibraltar Straits

2017

The creation of geographic barriers has long been suspected to contribute to the formation of new species. We investigated the phylogeography of desert ants in the western Mediterranean basin in order to elucidate their mode of diversification. These insects which have a low dispersal capacity are recently becoming important model systems in evolutionary studies. We conducted an extensive sampling of species belonging to the Cataglyphis albicans group in the Iberian Peninsula (IP) and the northern Morocco (North Africa; NA). We then combined genetic, chemical and morphological analyses. The results suggest the existence of at least three and five clades in the IP and NA, respectively, whose…

0106 biological sciences0301 basic medicineMaleParapatric speciation01 natural sciencesMediterranean BasinMonophylyfylogeografiaAfrica NorthernmuurahaisetPhylogenyComputingMilieux_MISCELLANEOUS[SDV.EE]Life Sciences [q-bio]/Ecology environmentLikelihood FunctionsPrincipal Component AnalysisbiologyEcologyCataglyphisDiscriminant Analysisgenital traitsBiological EvolutionEuropeMoroccoPhylogeographyAllopatric speciation010603 evolutionary biologythermophilyModels Biological03 medical and health sciencesGeneticsAnimalsMolecular BiologyEcology Evolution Behavior and SystematicsDemographyGibraltarAntscuticular hydrocarbonsGenetic VariationBayes Theorem15. Life on landbiology.organism_classificationHydrocarbonsEnvironmental niche modellingPhylogeography030104 developmental biologyCataglyphisglaciationsBiological dispersalta1181Microsatellite Repeats[SDV.EE.IEO]Life Sciences [q-bio]/Ecology environment/Symbiosis
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Benefits of immune protection versus immunopathology costs: a synthesis from cytokine KO models.

2017

5 pages; International audience; The inflammatory response can produce damage to host tissues and in several infectious diseases the most severe symptoms are due to immunopathology rather than a direct effect of pathogen multiplication. One hypothesis for the persistence of inflammatory damage posits that the benefits of protection towards infection outweigh the costs. We used data on knocked-out (KO) cytokine models [and the corresponding wild-type (WT) controls] to test this hypothesis. We computed differences in pathogen load and host survival between WT and KO and divided them by the WT values. Using this ratio provides an internal control for variation in pathogen species, host strain,…

0106 biological sciences0301 basic medicineMicrobiology (medical)medicine.medical_treatmentVirulenceInflammationImmunopathologyBiologyCommunicable Diseases010603 evolutionary biology01 natural sciencesMicrobiologyPersistence (computer science)Gene Knockout Techniques03 medical and health sciencesImmunopathologyGeneticsmedicine[ SDV.EE.IEO ] Life Sciences [q-bio]/Ecology environment/SymbiosisAnimalsHumans[ SDV.IMM ] Life Sciences [q-bio]/ImmunologyMolecular BiologyPathogenCytokineEcology Evolution Behavior and SystematicsInflammationVirulenceHost (biology)Immune protectionHost survivalComputational BiologyPathogen loadDisease Models Animal030104 developmental biologyInfectious DiseasesCytokineHost-Pathogen InteractionsImmunologyCytokinesmedicine.symptom
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Phosphinotripeptidic Inhibitors of Leucylaminopeptidases

2021

Phosphinate pseudopeptide are analogs of peptides containing phosphinate moiety in a place of the amide bond. Due to this, the organophosphorus fragment resembles the tetrahedral transition state of the amide bond hydrolysis. Additionally, it is also capable of coordinating metal ions, for example, zinc or magnesium ions. These two properties of phosphinate pseudopeptides make them an ideal candidate for metal-related protease inhibitors. This research investigates the influence of additional residue in the P2 position on the inhibitory properties of phosphinopeptides. The synthetic strategy is proposed, based on retrosynthetic analysis. The N-C-P bond formation in the desired compounds is …

0106 biological sciences0301 basic medicineModels MolecularMolecular modelQH301-705.5StereochemistryPhosphinesProtein ConformationSwineLAP inhibitorsligand-enzyme interactionPhosphinate01 natural sciencesAminopeptidaseCatalysisArticleInorganic Chemistry03 medical and health sciencesResidue (chemistry)phosphinate pseudopeptideLeucyl AminopeptidaseMoietyPeptide bondAnimalsBiology (General)Physical and Theoretical ChemistryEnzyme InhibitorsQD1-999Molecular BiologyMagnesium ionmolecular modeling; LAP inhibitors; barley aminopeptidase inhibitor; phosphinate pseudopeptide; ligand-enzyme interaction; organophosphorus compoundSpectroscopyChemistrymolecular modelingOrganic ChemistryGeneral Medicineorganophosphorus compoundPeptide FragmentsComputer Science ApplicationsChemistry030104 developmental biologybarley aminopeptidase inhibitorHordeum vulgare010606 plant biology & botanyInternational Journal of Molecular Sciences; Volume 22; Issue 10; Pages: 5090
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