Search results for " paediatrics"

showing 10 items of 56 documents

Menopause and diabetes: EMAS clinical guide

2018

Abstract Introduction Whether menopause increases the risk of type 2 diabetes mellitus (T2DM) independently of ageing has been a matter of debate. Controversy also exists about the benefits and risks of menopausal hormone therapy (MHT) in women with T2DM. Aims To summarise the evidence on 1) the effect of menopause on metabolic parameters and the risk of T2DM, 2) the effect of T2DM on age at menopause, 3) the effect of MHT on the risk of T2DM, and 4) the management of postmenopausal women with T2DM. Materials and methods Literature review and consensus of experts’ opinions. Results and conclusion Metabolic changes during the menopausal transition include an increase in and the central redis…

ESTROGEN REPLACEMENTmedicine.medical_specialtyHORMONE-REPLACEMENT THERAPYendocrine system diseasesmedicine.medical_treatment030209 endocrinology & metabolismDiseaseDydrogesteroneGeneral Biochemistry Genetics and Molecular Biology03 medical and health sciences0302 clinical medicine3123 Gynaecology and paediatricsRisk FactorsInternal medicineDiabetes mellitusType 2 diabetes mellitusDiabetes MellitusmedicineHumansNATURAL MENOPAUSEMenopausal hormone therapy; Menopause; Type 2 diabetes mellitus; Estrogen Replacement Therapy; Female; Humans; Incidence; Risk Factors; Diabetes Mellitus Type 2; MenopauseESTRADIOLMETABOLIC SYNDROME030219 obstetrics & reproductive medicineProgestogenINSULIN SENSITIVITYbusiness.industryIncidenceEstrogen Replacement TherapyENERGY-EXPENDITUREnutritional and metabolic diseasesObstetrics and GynecologyType 2 Diabetes MellitusHormone replacement therapy (menopause)medicine.disease3. Good healthMenopausePOSTMENOPAUSAL WOMENDiabetes Mellitus Type 23121 General medicine internal medicine and other clinical medicineRISK-FACTORSFemaleHEALTHMenopauseMetabolic syndromebusinessType 2Menopausal hormone therapymedicine.drug
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How do early family systems predict emotion recognition in middle childhood?

2021

Facial emotion recognition (FER) is a fundamental element in human interaction. It begins to develop soon after birth and is important in achieving developmental tasks of middle childhood, such as developing mutual friendships and acquiring social rules of peer groups. Despite its importance, FER research during middle childhood continues to be rather limited. Moreover, research is ambiguous on how the quality of one's early social-emotional environment shapes FER development, and longitudinal studies spanning from infancy to later development are scarce. In this study, we examine how the cohesive, authoritarian, disengaged and enmeshed family system types, assessed during pregnancy and inf…

EXPRESSIONSociology and Political Science515 Psychologylapset (ikäryhmät)sosiaalinen vuorovaikutusMiddle childhoodkehityspsykologia050105 experimental psychologymiddle childhoodDevelopmental psychologyCompetence (law)Person orientedkouluikäisettunteet3123 Gynaecology and paediatricsemotion recognitionDevelopmental and Educational Psychologyearly social-emotional environment0501 psychology and cognitive sciencesFamily systemsKNOWLEDGEEmotion recognitionsosiaalinen kehitysSocial informationlapsen kehitysperson-orientedCONFLICT05 social sciencesSOCIAL INFORMATIONCHILDRENS RECOGNITIONCOMPETENCEperhetaustaATTACHMENTMODELfamily systemExpression (architecture)perhesuhteetADOLESCENCEPsychologySocial Sciences (miscellaneous)BEHAVIOR050104 developmental & child psychologykasvontunnistus (kognitio)
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sj-jpg-1-tau-10.1177_1756287221995683 – Supplemental material for Fibronectin urothelial gene expression as a new reliable biomarker for early detect…

2021

Supplemental material, sj-jpg-1-tau-10.1177_1756287221995683 for Fibronectin urothelial gene expression as a new reliable biomarker for early detection of local toxicity secondary to adjuvant intravesical therapy for non-muscle invasive bladder cancer by Fabrizio Di Maida, Cristina Scalici Gesolfo, Riccardo Tellini, Andrea Mari, Chiara Sanfilippo, Luca Lambertini, Antonio Andrea Grosso, Marco Carini, Andrea Minervini and Vincenzo Serretta in Therapeutic Advances in Urology

FOS: Clinical medicine111403 Paediatrics111599 Pharmacology and Pharmaceutical Sciences not elsewhere classified
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sj-pdf-1-smo-10.1177_20503121211019889 – Supplemental material for The efficacy of single suture for exit site wound closure and stabilization of hem…

2021

Supplemental material, sj-pdf-1-smo-10.1177_20503121211019889 for The efficacy of single suture for exit site wound closure and stabilization of hemodialysis central tunneled catheter by Tomasz Porazko, Andrzej Piersiak and Marian Klinger in SAGE Open Medicine

FOS: Veterinary sciences111199 Nutrition and Dietetics not elsewhere classifiedCardiology170199 Psychology not elsewhere classified111799 Public Health and Health Services not elsewhere classified110604 Sports MedicineFOS: Health sciences110306 Endocrinology110308 Geriatrics and Gerontology111099 Nursing not elsewhere classified111708 Health and Community Services160807 Sociological Methodology and Research Methods111702 Aged Health Care111403 Paediatrics110904 Neurology and Neuromuscular Diseases110203 Respiratory Diseases110315 Otorhinolaryngology70706 Veterinary MedicineFOS: Clinical medicinefungi110319 Psychiatry (incl. Psychotherapy)FOS: SociologyFOS: Psychology110599 Dentistry not elsewhere classified110323 Surgery110305 Emergency Medicine111599 Pharmacology and Pharmaceutical Sciences not elsewhere classified111299 Oncology and Carcinogenesis not elsewhere classified110314 Orthopaedics
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sj-pdf-1-smo-10.1177_20503121211019889 – Supplemental material for The efficacy of single suture for exit site wound closure and stabilization of hem…

2021

Supplemental material, sj-pdf-1-smo-10.1177_20503121211019889 for The efficacy of single suture for exit site wound closure and stabilization of hemodialysis central tunneled catheter by Tomasz Porazko, Andrzej Piersiak and Marian Klinger in SAGE Open Medicine

FOS: Veterinary sciences111199 Nutrition and Dietetics not elsewhere classifiedCardiology170199 Psychology not elsewhere classified111799 Public Health and Health Services not elsewhere classified110604 Sports MedicineFOS: Health sciences110306 Endocrinology110308 Geriatrics and Gerontology111099 Nursing not elsewhere classified111708 Health and Community Services160807 Sociological Methodology and Research Methods111702 Aged Health Care111403 Paediatrics110904 Neurology and Neuromuscular Diseases110203 Respiratory Diseases110315 Otorhinolaryngology70706 Veterinary MedicineFOS: Clinical medicinefungi110319 Psychiatry (incl. Psychotherapy)FOS: SociologyFOS: Psychology110599 Dentistry not elsewhere classified110323 Surgery110305 Emergency Medicine111599 Pharmacology and Pharmaceutical Sciences not elsewhere classified111299 Oncology and Carcinogenesis not elsewhere classified110314 Orthopaedics
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Calcium in the prevention of postmenopausal osteoporosis: EMAS clinical guide

2017

Abstract Introduction Postmenopausal osteoporosis is a highly prevalent disease. Prevention through lifestyle measures includes an adequate calcium intake. Despite the guidance provided by scientific societies and governmental bodies worldwide, many issues remain unresolved. Aims To provide evidence regarding the impact of calcium intake on the prevention of postmenopausal osteoporosis and critically appraise current guidelines. Materials and methods Literature review and consensus of expert opinion. Results and conclusion The recommended daily intake of calcium varies between 700 and 1200 mg of elemental calcium, depending on the endorsing source. Although calcium can be derived either fro…

Genetics and Molecular Biology (all)OsteoporosisElemental calciumDiseaseDAIRY-PRODUCTSBiochemistrylaw.inventionCalcium; Diet; Excess-calcium risk; Postmenopausal osteoporosis; Prevention; Biochemistry Genetics and Molecular Biology (all); Obstetrics and GynecologyFractures Bone0302 clinical medicineRandomized controlled trial3123 Gynaecology and paediatricslawVITAMIN-D SUPPLEMENTATION030212 general & internal medicineVitamin DOsteoporosis PostmenopausalDIETARY CALCIUMObstetrics and GynecologyVitaminsRANDOMIZED CONTROLLED-TRIAL3. Good healthCARDIOVASCULAR-DISEASEDietary Reference IntakeFemalemedicine.medical_specialtychemistry.chemical_element030209 endocrinology & metabolismCalciumReference Daily IntakeGeneral Biochemistry Genetics and Molecular Biology03 medical and health sciencesPostmenopausal osteoporosisInternal medicinemedicineVitamin D and neurologyHumansCORONARY-HEART-DISEASESYMPTOMATIC KIDNEY-STONESIntensive care medicinebusiness.industryPreventionSERUM-CALCIUMUPDATED METAANALYSISmedicine.diseaseFRACTURE PREVENTIONDietCalcium DietaryExcess-calcium riskEndocrinologychemistryDietary SupplementsOsteoporosisCalciumbusinessMaturitas
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Transforming Obesity Prevention for CHILDren (TOPCHILD) Collaboration: protocol for a systematic review with individual participant data meta-analysi…

2022

ABSTRACTIntroductionBehavioural interventions in early life appear to show some effect in reducing childhood overweight and obesity. However, uncertainty remains regarding their overall effectiveness, and whether effectiveness differs among key subgroups. These evidence gaps have prompted an increase in very early childhood obesity prevention trials worldwide. Combining the individual participant data (IPD) from these trials will enhance statistical power to determine overall effectiveness and enable examination of intervention-covariate interactions. We present a protocol for a systematic review with IPD meta-analysis to evaluate the effectiveness of obesity prevention interventions commen…

GerontologyobesityPediatric ObesityMEDLINEPsychological interventionCINAHLPsycINFOpreventive medicineChildhood obesityBody Mass IndexpaediatricsMeta-Analysis as TopicBehavior TherapyMedicine and Health SciencesmedicineHumansEarly childhoodProspective Studies1506ChildExerciseASSOCIATIONSResearch ethicsOVERWEIGHTbusiness.industrypublic healthRInfantGeneral Medicinemedicine.diseaseRANDOMIZED-TRIALSBODY-MASS INDEX000 DAYSPHYSICAL-ACTIVITYMeta-analysisChild PreschoolRISK-FACTORS1114 Paediatrics and Reproductive MedicineMedicineWEIGHTHEALTHTRAJECTORIESbusiness1ST 1Developmental Psychopathology1719community child healthSystematic Reviews as Topic
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Impact of maternal body mass index and gestational weight gain on pregnancy complications: an individual participant data meta-analysis of European, …

2019

ObjectiveTo assess the separate and combined associations of maternal pre‐pregnancy body mass index (BMI) and gestational weight gain with the risks of pregnancy complications and their population impact.DesignIndividual participant data meta‐analysis of 39 cohorts.SettingEurope, North America, and Oceania.Population265 270 births.MethodsInformation on maternal pre‐pregnancy BMI, gestational weight gain, and pregnancy complications was obtained. Multilevel binary logistic regression models were used.Main outcome measuresGestational hypertension, pre‐eclampsia, gestational diabetes, preterm birth, small and large for gestational age at birth.ResultsHigher maternal pre‐pregnancy BMI and gesta…

Gestational hypertensionand promotion of well-beingNutrition and DiseaseBirthweightReproductive health and childbirthLow Birth Weight and Health of the NewbornCardiovascularMedical and Health SciencesDISEASECohort Studies0302 clinical medicine3123 Gynaecology and paediatricsRisk FactorsPregnancyVoeding en ZiekteInfant MortalityOdds RatioMedicineBirth Weight2.1 Biological and endogenous factorsEPIDEMIOLOGYwq_200Aetiology2. Zero hungerPediatricRISKeducation.field_of_studyOUTCOMES030219 obstetrics & reproductive medicineObstetricspregnancy complicationsDiabetesObstetrics and GynecologyGestational ageweight gainASSOCIATIONGestational Weight GainGestational diabetesEuropeBirthweight ; Body Mass Index ; Pregnancy Complications ; Preterm Birth ; Weight GainOBESITYFemalemedicine.symptomAdultmedicine.medical_specialtyPRETERM BIRTHBirth weightPopulationGestational Agebody mass index[SDV.MHEP.GEO]Life Sciences [q-bio]/Human health and pathology/Gynecology and obstetricswa_310Healthcare improvement science Radboud Institute for Health Sciences [Radboudumc 18]03 medical and health sciencesAll institutes and research themes of the Radboud University Medical CenterPretermClinical ResearchHumanswq_100ObesityeducationObstetrics & Reproductive MedicineMetabolic and endocrineNutritionPregnancybusiness.industryContraception/ReproductionPreventionBirthweight; body mass index; pregnancy complications; preterm birth; weight gainAustraliaInfantbirth weightpreterm birthDIABETES-MELLITUSPreterm birth weight gainOverweightPerinatal Period - Conditions Originating in Perinatal Periodmedicine.diseaseNewbornPrevention of disease and conditionsReconstructive and regenerative medicine Radboud Institute for Health Sciences [Radboudumc 10]Good Health and Well BeingNorth America3.1 Primary prevention interventions to modify behaviours or promote wellbeingpregnancy complicationbusinessWeight gainBody mass indexwb_200
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Associations of partnering transition and socioeconomic status with a four-year change in daily steps among Finnish adults

2019

Aim: The aim of this prospective four-year follow-up study was to examine how socioeconomic status (SES) and change in marital status are associated with the change in pedometer-measured physical activity (PA) in adulthood among participants in the ‘Cardiovascular Risk in Young Finns Study’. Methods: Questionnaires were completed and pedometers worn at baseline in 2007 and again at follow-up in 2011 by 1051 Finnish adults (62.3% female, aged 30–45 years in 2007). A latent change score model was used to examine mean change in daily total steps, aerobic steps and non-aerobic steps during weekdays and weekend days between 2007 and 2011. Results: In women re-coupling or finding a new partner wa…

Kansanterveystiede ympäristö ja työterveys - Public health care science environmental and occupational healthsiviilisäätyphysical activityNaisten- ja lastentaudit - Gynaecology and paediatricssosioekonominen asemasocioeconomic statusPedometeradultsfollow-upseurantatutkimusfyysinen aktiivisuusaskelmittaritaikuisetmarital status
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Sirolimus treatment of severe PTEN hamartoma tumor syndrome: case report and in vitro studies

2013

Background: Phosphatase and tensin homolog (PTEN) hamartoma tumor syndrome (PHTS) is caused by germ line mutations in the PTEN gene. Symptoms include cancer pre- disposition, immune deviations, and lipomas/lipomatosis. No causal standard therapy is available. We describe a therapeutic attempt with the mammalian target of rapamycin (mTOR) inhibitor sirolimus for a PHTS patient suffering from thymus hyperplasia and lipomatosis. We furthermore assessed the in vitro effects of sirolimus and other inhibitors on lipoma cells of the patient. Methods: The patient underwent clinical and blood examinations and whole-body magnetic resonance imaging to assess tumor sizes. Lipoma cells of the patient we…

LipomatosisIn Vitro TechniquesDrug therapy Hamartoma Paediatrics PTEN PHTS PI3K AKT mTORmedicineHumansTensinPTENddc:610Protein kinase BPI3K/AKT/mTOR pathwaySirolimusbiologybusiness.industryInfant NewbornPTEN PhosphohydrolaseInfantLipomamedicine.diseaseChild PreschoolSirolimusPediatrics Perinatology and Child HealthCancer researchbiology.proteinThymus hyperplasiaHamartoma Syndrome Multiplebusinessmedicine.drugPediatric Research
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