Search results for " pediatria"

showing 10 items of 667 documents

Lessons from the COVID-19 Pandemic—Unique Opportunities for Unifying, Revamping and Reshaping Epidemic Preparedness of Europe’s Public Health Systems

2020

Microbiology (medical)2019-20 coronavirus outbreakEconomic growthmedicine.medical_specialtyCoronavirus disease 2019 (COVID-19)Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Public healthCOVID-19General Medicinelcsh:Infectious and parasitic diseasesInfectious DiseasesSettore MED/38 - PEDIATRIA GENERALE E SPECIALISTICAPreparednessPolitical sciencePandemicmedicinelcsh:RC109-216International Journal of Infectious Diseases
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Is the monoclonal spread of the ST258, KPC-3-producing clone being replaced in southern Italy by the dissemination of multiple clones of carbapenem-n…

2015

D. M. Geraci, C. Bonura, M. Giuffre, L. Saporito, G. Graziano, A. Aleo, T. Fasciana, F. Di Bernardo, T. Stampone, D. M. Palma and C. Mammina 1) Department of Sciences for Health Promotion and Mother-Child Care ‘G. D’Alessandro’, University of Palermo, 2) Postgraduate Specialty School in Hygiene and Preventive Medicine, University of Palermo, 3) Laboratory of Microbiology, General Hospital ARNAS ‘Civico, Di Cristina & Benfratelli’, 4) Laboratory of Microbiology, General Hospital Azienda Ospedaliera ‘Villa Sofia-V, Cervello’ and 5) II Intensive Care Unit, General Hospital ARNAS ‘Civico, Di Cristina & Benfratelli’, Palermo, Italy

Microbiology (medical)CarbapenemSettore MED/07 - Microbiologia E Microbiologia ClinicaKlebsiella pneumoniaeKPC Klebsiella pneumoniae epidemiology multidrug resistanceSettore MED/42 - Igiene Generale E Applicatabeta-Lactam Resistancebeta-LactamasesMicrobiologySettore MED/38 - Pediatria Generale E SpecialisticaBacterial ProteinsMedicineHumansGeneral hospitalbiologybusiness.industryGeneral Medicinebiology.organism_classificationKlebsiella InfectionsKlebsiella pneumoniaeInfectious DiseasesCarbapenemsItalybusinessHumanitiesmedicine.drugClinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases
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MRSA infection in the neonatal intensive care unit

2013

Methicillin-resistant Staphylococcus aureus (MRSA) is well known as one of the most frequent etiological agents of healthcare-associated infections. The epidemiology of MRSA is evolving with emergence of community-associated MRSA, the clonal spread of some successful clones, their spillover into healthcare settings and acquisition of antibacterial drug resistances. Neonatal intensive care unit (NICU) patients are at an especially high risk of acquiring colonization and infection by MRSA. Epidemiology of MRSA in NICU can be very complex because outbreaks can overlap endemic circulation and make it difficult to trace transmission routes. Moreover, increasing prevalence of community-associated…

Microbiology (medical)Methicillin-Resistant Staphylococcus aureusmedicine.medical_specialtyNeonatal intensive care unitMRSA infectionSettore MED/42 - Igiene Generale E ApplicataMicrobiologySettore MED/38 - Pediatria Generale E SpecialisticaVirologyIntensive Care Units NeonatalEpidemiologymedicinePrevalenceInfection controlHumansIntensive care medicineAntibacterial drugDeveloping CountriesInfection Controlbusiness.industryTransmission (medicine)Developed CountriesAustraliaInfant NewbornMRSA CA-MRSA HA-MRSA NICU epidemiology prevention controlOutbreakbiochemical phenomena metabolism and nutritionStaphylococcal Infectionsbacterial infections and mycosesUnited StatesAnti-Bacterial AgentsEuropeInfectious DiseasesEpidemiological MonitoringEpidemiological Monitoringbusiness
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incidence and risk factors of bacterial sepsis and invasive fungal infection in neonates and infants requiring major surgery: an Italian multicentre …

2022

Background: Limited data are currently available on the incidence rates and risk factors for bacterial sepsis and invasive fungal infections (IFIs) among neonates and infants undergoing major surgery. Aim: To assess the incidence of bacterial sepsis and IFI, fungal colonization, risk factors for sepsis, and mortality in neonates and infants aged <3 months undergoing major surgery. Methods: A multicentre prospective study was conducted involving 13 level-3 neonatal intensive care units in Italy, enrolling all infants aged ≤3 months undergoing major surgery. Findings: From 2018 to 2021, 541 patients were enrolled. During hospitalization, 248 patients had a bacterial infection, and 23 patie…

Microbiology (medical)Settore MED/38 - Pediatria Generale e SpecialisticaFungal infectionAntifungal AgentsIncidenceInfant NewbornInfantGeneral MedicineCandida; Fungal colonization; Fungal infection; Neonatal sepsis; SurgerySurgery.Infectious DiseasesMycosesRisk FactorsSepsisNeonatal sepsisHumansSurgeryProspective StudiesNeonatal sepsifungal infection Fungal colonization Neonatal sepsis Surgery CandidaInvasive Fungal InfectionsCandidaFungal colonization
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Surgical Antimicrobial Prophylaxis in Pediatric Patients Undergoing Plastic Surgery: A RAND/UCLA Appropriateness Method Consensus Study

2022

For many years, it was clearly shown that surgical procedures might be associated with surgical site infection (SSI). Many scientific institutions prepared guidelines to use in surgery to reduce abuse and misuse of antibiotics. However, in the general guidelines for surgical antibiotic prophylaxis, plastic surgical procedures are not addressed or are only marginally discussed, and children were almost systematically excluded. The main aim of this Consensus document is to provide clinicians with recommendations on antimicrobial prophylaxis for pediatric patients undergoing plastic surgery. The following scenarios were considered: clean plastic surgery in elective procedures with an exclusive…

Microbiology (medical)Settore MED/38 - Pediatria Generale e SpecialisticawoundBiochemistryMicrobiologyantibiotics; burn; pediatric infectious diseases; plastic surgery; surgical antibiotic prophylaxis; woundantibioticspediatric infectious diseaseInfectious Diseasessurgical antibiotic prophylaxisantibioticplastic surgeryburnPharmacology (medical)surgical antibiotic prophylaxiGeneral Pharmacology Toxicology and PharmaceuticsKeywords: antibioticpediatric infectious diseaseswound.
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Characterization of a complex rearrangement involving chromosomes 1, 4 and 8 by fish and array-CGH

2012

Complex chromosomal rearrangements (CCRs) are structural aberrations involving more than two chromosomes with at least three breakpoints. CCRs can be divided into familial and de novo. Balanced CCR are extremely rare in humans and are at high risk of producing unbalanced gametes. Individuals with balanced CCR are usually phenotipically normal but report fertility problems, recurrent miscarriages or congenital anomalies in newborn offsprings as consequence of either meiotic failure or imbalanced chromosomes segregation.We describe the case of an unbalanced CCR involving chromosomes 1, 4 and 8 found in a girl with developmental delay, hexadactilia and microcephaly. The rearrangement, apparent…

MicrocephalyArray-CGHIntellectual disabilityChromosomal rearrangementBiologySettore MED/38 - Pediatria Generale E SpecialisticaFISHMeiosisGeneticsmedicineChromosomes HumanHumansIn Situ Hybridization FluorescenceGene RearrangementGeneticsComparative Genomic HybridizationComplex chromosomal rearrangementBreakpointInfant NewbornInfantChromosomeKaryotypeGeneral Medicinemedicine.diseaseHuman geneticsChromosome BandingSettore MED/03 - Genetica MedicaChromosomes Human Pair 1KaryotypingFish <Actinopterygii>FemaleChromosomes Human Pair 4Chromosomes Human Pair 8Journal of Applied Genetics
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Road Traffic Pollution and Childhood Leukemia: A Nationwide Case-control Study in Italy

2016

Background The association of childhood leukemia with traffic pollution was considered in a number of studies from 1989 onwards, with results not entirely consistent and little information regarding subtypes. Aim of the study We used the data of the Italian SETIL case-control on childhood leukemia to explore the risk by leukemia subtypes associated to exposure to vehicular traffic. Methods We included in the analyses 648 cases of childhood leukemia (565 Acute lymphoblastic–ALL and 80 Acute non lymphoblastic-AnLL) and 980 controls. Information on traffic exposure was collected from questionnaire interviews and from the geocoding of house addresses, for all periods of life of the children. Re…

MyeloidMaleFuture studies010501 environmental sciencesSettore MED/42 - Igiene Generale E Applicata01 natural sciences0302 clinical medicineEconomicahemic and lymphatic diseasesMedicine030212 general & internal medicineChildRoad trafficacute non lymphoblastic leukemia; childhood; environment; leukemia; road traffic; air pollution; case-control studies; child; child preschool; female; humans; infant; Italy; leukemia myeloid acute; male; precursor cell lymphoblastic leukemia-lymphoma; risk; motor vehicles; medicine (all)LeukemiaTraffic pollutionMedicine (all)General MedicinePrecursor Cell Lymphoblastic Leukemia-LymphomaLeukemiaMotor VehiclesLeukemia Myeloid AcuteItalyAcute non Lymphoblastic LeukemiaSettore MED/38 - PEDIATRIA GENERALE E SPECIALISTICARoad TrafficChild PreschoolFemaleMedical emergencyCase-Control StudieHumanRiskChildhood leukemiaSocio-culturaleAcuteEnvironmentPrecursor Cell Lymphoblastic Leukemia Lymphoma03 medical and health sciencesEnvironmental healthAir PollutionHumansPreschool0105 earth and related environmental sciencesbusiness.industryCase-control studyType specificAmbientaleInfantmedicine.diseaseChildhoodCase-Control StudiesMotor Vehiclebusiness
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Trattamento della Nefrite Lupica in età pediatrica: dalla clinical practice alla letteratura

2021

Nefrite Lupica Lupus Eritematoso SistemicoSettore MED/38 - Pediatria Generale E Specialistica
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PTEN hamartoma tumor syndromes in childhood: description of two cases and a proposal for follow-up protocol

2013

PTEN hamartoma tumor syndromes (PHTS) are a spectrum of hamartomatous overgrowth syndromes associated with germ-line mutations in the tumor suppressor PTEN gene located on 10q23.3. It is widely accepted that two of these disorders, Cowden syndrome and Bannayan-Riley-Ruvalcaba syndrome, are allelic conditions. Because PTEN mutations are not identifiable in every case of the PHTS phenotype, the inability to detect a mutation within the PTEN gene does not invalidate the clinical diagnosis of Cowden syndrome, or Bannayan-Riley-Ruvalcaba syndrome, in patients who meet diagnostic criteria for these disorders. PTEN mutations are associated with an increased risk for developing breast, thyroid, end…

OncologyPTENmedicine.medical_specialtymedicine.disease_causeBannayan–Riley–Ruvalcaba syndromeSettore MED/38 - Pediatria Generale E SpecialisticaInternal medicineGeneticsmedicinePTEN Hamartoma tumor syndromeHamartomaPTENAllelePTEN Hamartoma tumor syndromes; PTEN gene; Cowden syndrome; Bannayan-Riley-Ruvalcaba syndromGenetics (clinical)Bannayan-Riley-Ruvalcaba syndromMutationbiologybusiness.industryThyroidCancerCowden syndromeCowden syndromePTEN genemedicine.diseasemedicine.anatomical_structureSettore MED/31 - OtorinolaringoiatriaSettore MED/03 - Genetica Medicabiology.proteinCancer researchbusiness
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PAPA syndrome: novelties from the Eurofever registry

2019

Introduction: PAPA syndrome is a very rare autoinflammatory condition. Few data are nowadays available about the clinical characteristic, the response to treatment and the outcome of this disease. Objectives:To analyse the data of the PAPA patients enrolled to the Eurofever registry. Methods: the data analysed in the study were extracted from the Eurofever registry, which is hosted in the PRINTO website (www.printo. it). The patients were included in the study in the presence of mutations in the PSTPIP1 gene or, in genetically negative patients, in the presence of at least two of the following clinical manifestation: recurrent pyogenic arthritis, pyoderma gangrenousm or skin abscess with ne…

PAPA Eurofever registry Pyogenic arthritis Pyoderma gangrenousmSettore MED/38 - Pediatria Generale E Specialistica
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