Search results for " protocol"
showing 10 items of 1320 documents
Translation through Visualization
2005
There are many aspect of professional translation. Problem solving is certainly one of them, and visualization has occasionally been recommended in this context. In this article, think aloud protocols (dialogue protocols) are analysed with the aim of observing instances of visualizations that lead to successful translations. As a heuristic means cognitive notions (prototypes, scenes and frames and focus) are used. In general, it seems that visualizing details of a scene helps translators to arrive at creative translations.
A Multi-Phase Decode-and-Forward Transmission Protocol in Cognitive Relay Networks: Outage Analysis and Relay Power Allocation
2015
Consider an underlay cognitive relay network with multiple source and destination pairs and that a decode-and-forward scheme is adopted at the relay. We propose a multi-phase transmission protocol in this paper which involves cooperation among source, relay and destination nodes. Given perfect interference elimination before decoding at the destination nodes, we derive closed-form expressions for outage probability calculation over Rayleigh fading channels. Furthermore, the optimal relay power allocation factor which leads to minimal outage probability is determined. Numerical results reveal the conditions under which satisfactory performance can be achieved based on the proposed scheme.
Is TCP Packet Reordering Always Harmful?
2004
IP networks do not provide any guarantee that packets belonging to the same flow are delivered in the correct order. Out-of-order reception of packets was commonly considered due to pathological network conditions (such as link failures, etc.). However, it has been shown that packet reordering is a phenomenon which occurs even in normal network operation, due to a number of link-level and/or router-level implementation features, such as local parallelism and load balancing. Packet reordering is intuitively considered as a negative phenomenon, which may severely affect TCP traffic performance since it is expected to cause inefficient usage of the available link bandwidth and is expected to i…
Seeding after radiofrequency ablation of hepatocellular carcinoma in patients with cirrhosis: a prospective study.
2008
Abstract Background Neoplastic seeding of hepatocellular carcinoma may arise after radiofrequency ablation. Aims In order to clarify the real risk of seeding, we observed a prospective cohort of patients undergoing radiofrequency ablation. Methods Ninety-three (22.9%) out of 406 consecutive patients with hepatocellular carcinoma superimposed to cirrhosis diagnosed at our Liver Unit (2000–2005) were selected for radiofrequency ablation according to the Barcelona 2000 EASL guidelines. Seventy-one patients were treated by a percutaneous approach and 22 at laparotomy. After radiofrequency ablation ultrasound scan was repeated every 3 months and spiral-computed tomography every 6 months. Results…
Multisciplinary management of patients with liver metastasis from colorectal cancer
2016
Abstract: Colorectal cancer (CRC) is one of the leading causes of cancer-related death. Surgery, radiotherapy and chemotherapy have been till now the main therapeutic strategies for disease control and improvement of the overall survival. Twenty-five per cent (25%) of CRC patients have clinically detectable liver metastases at the initial diagnosis and approximately 50% develop liver metastases during their disease course. Twenty-thirty per cent (20%-30%) are CRC patients with metastases confined to the liver. Some years ago various studies showed a curative potential for liver metastases resection. For this reason some authors proposed the conversion of unresectable liver metastases to res…
A Coexistence Analysis of Blockchain, SCADA Systems, and OpenADR for Energy Services Provision
2022
The advent of blockchain technology allows the raise of new business models for the electricity market, opening the way also to end-users and letting them offer regulation services to the power grid. Thanks to the characteristic of being distributed, the blockchain technology could be a solution to balancing problems caused by the penetration of renewable sources, implementing a platform for Demand-Response programs delivery. Demand-Response allows consumers to respond to market signals by increasing or reducing their energy consumption, contributing to greater flexibility and stability of the grid and to a more efficient use of infrastructures and energy resources. Currently, Demand-Respon…
Driver mutations and differential sensitivity to targeted therapies: a new approach to the treatment of lung adenocarcinoma
2010
The adenocarcinoma of the lung has recently shown peculiar molecular characteristics, which relate with both carcinogenesis and response to targeted drugs. Several molecular alterations have been defined as "driver mutations". These are responsible for both the initiation and maintenance of the malignancy. The epidermal growth factor receptor (EGFR) pathway is the main regulator of cell function and cancer development. It has a widely defined role in the occurrence of driver mutations. Up till now EGFR gene mutations, KRAS gene mutations and EML4-ALK fusion genes are the most widely recognized alterations involved in both the biology and the clinical management of lung adenocarcinoma. In th…
Novel therapeutic strategies for patients with NSCLC that do not respond to treatment with EGFR inhibitors
2014
Abstract: Introduction: Treatment with epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) yields tumour responses in non-small cell lung cancer (NSCLC) patients harbouring activating EGFR mutations. However, even in long-lasting responses, resistance to EGFR TKIs invariably occurs. Areas covered: This review examines resistance mechanisms to EGFR TKI treatment, which mainly arise from secondary EGFR mutations. Other resistance-inducing processes include mesenchymal-epithelial transition factor (MET) amplification, epithelial-mesenchymal transformation, phenotypic change from NSCLC to small-cell lung carcinoma, and modifications in parallel signalling pathways. Current…
Non-linear protocols for optimal distributed consensus in networks of dynamic agents
2006
We consider stationary consensus protocols for networks of dynamic agents with fixed topologies. At each time instant, each agent knows only its and its neighbors'' state, but must reach consensus on a group decision value that is function of all the agents'' initial state. We show that the agents can reach consensus if the value of such a function is time-invariant when computed over the agents'' state trajectories. We use this basic result to introduce a non-linear protocol design rule allowing consensus on a quite general set of values. Such a set includes, e.g., any generalized mean of order p of the agents'' initial states. As a second contribution we show that our protocol design is t…
Emerging MEK inhibitors
2010
IMPORTANCE OF THE FIELD: The Ras/Raf/MEK/ERK pathway is often activated by genetic alterations in upstream signaling molecules. Integral components of this pathway such as Ras and B-Raf are also activated by mutation. The Ras/Raf/MEK/ERK pathway has profound effects on proliferative, apoptotic and differentiation pathways. This pathway can often be effectively silenced by MEK inhibitors. AREAS COVERED BY THIS REVIEW: This review will discuss targeting of MEK which could lead to novel methods to control abnormal proliferation which arises in cancer and other proliferative diseases. This review will cover the scientific literature from 1980 to present and is a follow on from a review which fo…