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showing 10 items of 2362 documents

Results of the Thyroid Cancer Alliance international patient/survivor survey: Psychosocial/informational support needs, treatment side effects and in…

2013

To comprehensively assess the experience of a large, diverse cohort and identify potential care improvements, the Thyroid Cancer Alliance, an international patient/survivor group coalition, surveyed thyroid cancer patients/survivors worldwide.English, German, French or Spanish versions of a self-developed 43-item questionnaire were completed, predominantly online, by 2398 respondents from the US (37.9%), Germany (21.3%), the UK (11.5%), Canada (11.4%), France (9%), and 35 other countries. Females and differentiated thyroid carcinoma patients each comprised ~87% of respondents. Diagnosis occurred at age 30-59 years in 71.8%, within1 (1-5) year(s) before survey completion in 16.4% (55%).At di…

AdultMalemedicine.medical_specialtyCanadaReferralCross-sectional studyEndocrinology Diabetes and MetabolismThyroid carcinomaCohort StudiesIodine RadioisotopesSocial supportGermanySurveys and QuestionnairesmedicineHumansSurvivorsThyroid NeoplasmsThyroid cancerReferral and Consultationbusiness.industrySocial SupportGeneral MedicineMiddle Agedmedicine.diseaseUnited KingdomUnited StatesCross-Sectional StudiesFamily medicineCohortThyroidectomyFemaleFrancebusinessPsychosocialStress PsychologicalCohort studyHormones (Athens, Greece)
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Evaluation of posttreatment response of hepatocellular carcinoma: comparison of ultrasonography with second-generation ultrasound contrast agent and …

2010

We evaluated the ability of one-month follow-up contrast-enhanced ultrasound (CEUS) with second-generation contrast agent in monitoring radio frequency ablation (RFA) and transcatheter arterial chemoembolization (TACE) treatments of hepatocellular carcinoma (HCC). One-hundred forty-eight HCCs were studied using CEUS: 110 nodules were treated with RFA [41/110 RFA were performed using a pretreatment and an immediate postablation evaluation using CEUS (group 1); 69/110 using only US guidance (group 2)] and 38 nodules treated with TACE. For statistical analysis, McNemar test was used. Overall complete response was observed in 107/148 nodules (92/110 treated with RFA and 15/38 with TACE). A bett…

AdultMalemedicine.medical_specialtyCarcinoma HepatocellularRadiofrequency ablationUrologymedicine.medical_treatmentSulfur HexafluorideContrast MediaCatheter ablationAntineoplastic AgentsSensitivity and Specificitylaw.inventionlawmedicineHumansRadiology Nuclear Medicine and imagingEmbolizationChemoembolization TherapeuticTranscatheter arterial chemoembolizationPhospholipidsAgedUltrasonographyRadiological and Ultrasound Technologymedicine.diagnostic_testbusiness.industryUltrasoundLiver NeoplasmsGastroenterologyGeneral MedicineMiddle Agedmedicine.diseasesurgical procedures operativeHepatocellular carcinomaAngiographyCatheter AblationFemaleRadiologyNuclear medicinebusinessTomography X-Ray ComputedSettore MED/36 - Diagnostica Per Immagini E RadioterapiaContrast-enhanced ultrasoundContrast-enhanced ultrasound—Radiofrequency ablation—Hepatocellular carcinoma—Transcatheter arterial chemoembolization—Computed tomography
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Integrating Downstaging in the Risk Assessment of Patients With Locally Advanced Rectal Cancer Treated With Neoadjuvant Chemoradiotherapy: Validation…

2017

Abstract Background Adjuvant chemotherapy is controversial in patients with locally advanced rectal cancer after preoperative chemoradiation. Valentini et al developed 3 nomograms (VN) to predict outcomes in these patients. The neoadjuvant rectal score (NAR) was developed after VN to predict survival. We aimed to validate these tools in a retrospective cohort at an academic institution. Patients and Methods VN and the NAR were applied to 158 consecutive patients with locally advanced rectal cancer treated with chemoradiation followed by surgery. According to the score, they were divided into low, intermediate, or high risk of relapse or death. For statistical analysis, we performed Kaplan-M…

AdultMalemedicine.medical_specialtyColorectal cancermedicine.medical_treatmentRectal neoplasms prognosisLocally advancedUrologyKaplan-Meier EstimateRisk AssessmentAdjuvant; Chemotherapy; Rectal neoplasms prognosis; Oncology; GastroenterologyDisease-Free Survival03 medical and health sciences0302 clinical medicinemedicineChemotherapyHumans030212 general & internal medicineAdjuvantSettore MED/36 - DIAGNOSTICA PER IMMAGINI E RADIOTERAPIAAgedNeoplasm StagingProportional Hazards ModelsRetrospective StudiesAged 80 and overChemotherapyRectal NeoplasmsProportional hazards modelbusiness.industryHazard ratioGastroenterologyRetrospective cohort studyChemoradiotherapy AdjuvantMiddle AgedNomogrammedicine.diseaseNeoadjuvant TherapySurgeryNomogramsTreatment OutcomeOncology030220 oncology & carcinogenesisFemaleRisk assessmentbusinessClinical Colorectal Cancer
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Three-dimensional images contribute to the diagnosis of mucous retention cyst in maxillary sinus

2011

Objective: To evaluate the detection of mucous retention cyst of maxillary sinus (MRCMS) using panoramic radiography and cone beam computed tomography (CBCT). Study Design: A digital database with 6,000 panoramic radiographs was reviewed for MRCMS. Suggestive images of MRCMS were detected on 185 radiographs, and patients were located and invited to return for follow-up. Thirty patients returned, and control panoramic radiographs were obtained 6 to 46 months after the initial radiograph. When MRCMS was found on control radiographs, CBCT scans were obtained. Cysts were measured and compared on radiographs and scans. The Wilcoxon, Spearman and Kolmorogov-Smirnov tests were used for statistical…

AdultMalemedicine.medical_specialtyCone beam computed tomographyPanoramic radiographMaxillary sinusAdolescentRadiographyOdontologíaYoung AdultImaging Three-DimensionalRadiography PanoramicmedicineParanasal Sinus DiseasesHumansStatistical analysisChildGeneral Dentistrybusiness.industryMucous retention cystCystsClinical and Experimental dentistryCone-Beam Computed TomographyMaxillary SinusMiddle Agedrespiratory systemmedicine.disease:CIENCIAS MÉDICAS [UNESCO]Ciencias de la saludrespiratory tract diseasesmedicine.anatomical_structureOtorhinolaryngologyUNESCO::CIENCIAS MÉDICASSurgeryFemaleResearch-ArticleRadiologybusiness
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Splenic hemangiomas: contrast-enhanced sonographic findings

2012

Objectives The purpose of this study was to illustrate the baseline appearance and enhancement patterns of splenic hemangiomas on contrast-enhanced sonography. Methods Two experienced radiologists retrospectively reviewed by consensus baseline and contrast-enhanced sonographic examinations of 27 patients (14 women and 13 men; mean age, 58.7 years) with 27 splenic hemangiomas (mean size, 2 cm) confirmed by splenectomy, biopsy, computed tomography, and magnetic resonance imaging and follow-up. Results On baseline sonography, 77.8% of the lesions showed a homogeneous echo texture that was mainly hyperechoic. Color Doppler imaging did not show any signal in 81.5% of the cases. After contrast ag…

AdultMalemedicine.medical_specialtyContrast-enhanced sonography; spleen; splenic hemangioma; splenic neoplasmsContrast enhancementmedicine.medical_treatmentmedia_common.quotation_subjectSplenectomySulfur HexafluorideContrast MediaSensitivity and SpecificityBiopsyParenchymaMedicineContrast (vision)HumansRadiology Nuclear Medicine and imagingPhospholipidsmedia_commonAgedUltrasonographyRadiological and Ultrasound Technologymedicine.diagnostic_testbusiness.industrySplenic NeoplasmsReproducibility of ResultsMagnetic resonance imagingMiddle AgedContrast-enhanced sonographyHomogeneousspleenFemaleRadiologybusinessHemangiomaSettore MED/36 - Diagnostica Per Immagini E Radioterapiasplenic hemangiomaArterial phase
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Influence of heart rate in the selection of the optimal reconstruction window in routine clinical multislice coronary angiography

2008

Purpose. The aim of our study was to assess the influence of heart rate on the selection of the optimal reconstruction window with 40-slice multidetector-row computed tomography (40-MDCT) coronary angiography. Materials and methods. We studied 170 patients (114 men, age 60 +/- 11.3 years) with suspected or known coronary artery disease with 40-MDCT coronary angiography. Patients [mean heart rate (HR) 62.9 +/- 9.3 bpm, range 42-94 bpm] were clustered in two groups (group A: HR <= 65 bpm; group B: HR >65 bpm). Multiphase reconstruction data sets were obtained with a retrospective electrocardiogram (ECG)-gated 40-MDCT coronary angiography scan from 0% to 95% every 5% of the R-R interval.…

AdultMalemedicine.medical_specialtyCoronary AngiographyHeart RateHeart rateImage Processing Computer-AssistedHumansMedicineRadiology Nuclear Medicine and imagingMultislicecardiovascular diseasesSelection (genetic algorithm)AgedNeuroradiologyAged 80 and overmedicine.diagnostic_testbusiness.industryUltrasoundWindow (computing)Interventional radiologyGeneral MedicineMiddle Agedcardiovascular systemFemaleTomographyRadiologyArtifactsTomography X-Ray ComputedbusinessRadiologia Medica
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Thromboembolic complications of COVID-19: the combined effect of a pro-coagulant pattern and an endothelial thrombo-inflammatory syndrome.

2020

Coronavirus disease 2019 (COVID-19) is a newly emerging human infectious disease that has quickly become a worldwide threat to health, mainly causing severe acute respiratory syndrome. In addition to the widely described respiratory syndrome, COVID-19 may cause life-treating complications directly or indirectly related to this infection. Among these, thrombotic complications have emerged as an important issue in patients with COVID-19 infection, particularly in patients in intensive care units. Thrombotic complications due to COVID-19 are likely to occur due to a pro-coagulant pattern encountered in some of these patients or to a progressive endothelial thrombo-inflammatory syndrome causing…

AdultMalemedicine.medical_specialtyCoronavirus disease 2019 (COVID-19)Pneumonia ViralDiseaseThromboembolic complicationsCOVID-19 CT ComplicationsSevere Acute Respiratory SyndromeCommunicable Diseases EmergingArticle030218 nuclear medicine & medical imagingBrain IschemiaThromboplastin03 medical and health sciences0302 clinical medicineIntensive careCause of DeathThromboembolismmedicineHumansRadiology Nuclear Medicine and imagingIn patientClinical significanceIntensive care medicinePandemicsAgedbusiness.industrypandemicAnticoagulantsCOVID-19General MedicineMiddle AgedstrokeSurvival AnalysisItalyRadiology Nuclear Medicine and imagingInfectious disease (medical specialty)030220 oncology & carcinogenesisFemaleRadiography ThoracicbusinessSettore MED/36 - Diagnostica Per Immagini E RadioterapiaCoronavirus InfectionsPulmonary EmbolismTomography X-Ray ComputedThrombotic complicationClinical radiology
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Radiation-related superficial oral mucoceles : an under-recognized acute toxicity in head and neck cancer patients

2018

Background Acute toxicity is usually defined as adverse changes occurring immediately or a short time after the start of oncological treatment. Material and Methods Cross-sectional retrospective study performed with head and neck cancer patients who underwent radiotherapy from 2013 to 2016. Results Ten (1.2%) patients developed SOMs during radiotherapy, most (80%) of which were men with a mean age of 59.5 years at diagnosis. SOMs mainly affected the floor of the mouth (60%) between the fourth and the sixth weeks of radiation therapy. All lesions were asymptomatic and spontaneously ruptured approximately 9 days after diagnosis. Conclusions Although rare, SOMs may be regarded as an acute oral…

AdultMalemedicine.medical_specialtyCross-sectional studymedicine.medical_treatmentMucoceleAsymptomaticHead and neck radiotherapymedicineCarcinomaHumansRadiation InjuriesGeneral DentistryAgedRetrospective StudiesOral Medicine and Pathologybusiness.industryResearchHead and neck cancerRetrospective cohort studyMiddle Agedmedicine.disease:CIENCIAS MÉDICAS [UNESCO]Acute toxicityRadiation therapyCross-Sectional StudiesOtorhinolaryngologyHead and Neck NeoplasmsUNESCO::CIENCIAS MÉDICASAcute DiseaseCarcinoma Squamous CellSurgeryFemaleRadiologymedicine.symptombusinessMouth Diseases
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Relationship between dopamine D2 receptor occupancy, clinical response, and drug and monoamine metabolites levels in plasma and cerebrospinal fluid. …

2009

Combining measurements of the monoamine metabolites in the cerebrospinal fluid (CSF) and neuroimaging can increase efficiency of drug discovery for treatment of brain disorders. To address this question, we examined five drug-naive patients suffering from schizophrenic disorder. Patients were assessed clinically, using the Positive and Negative Syndrome Scale (PANSS): at baseline and then at weekly intervals. Plasma and CSF levels of quetiapine and norquetiapine as well CSF 3,4-dihydroxyphenylacetic acid (DOPAC), homovanillic acid (HVA), 5-hydroxyindole-acetic acid (5-HIAA) and 3-methoxy-4-hydroxyphenylglycol (MHPG) were obtained at baseline and again after at least a 4 week medication trai…

AdultMalemedicine.medical_specialtyDibenzothiazepinesFluorine RadioisotopesPyrrolidinesmedicine.drug_classCaudate nucleusAtypical antipsychoticPilot ProjectsTritiumMethoxyhydroxyphenylglycolchemistry.chemical_compoundQuetiapine FumarateYoung AdultInternal medicinemedicineHumansBiogenic MonoaminesBiological PsychiatryTemporal cortexFirst episodeBrain Mappingbusiness.industryReceptors Dopamine D2Homovanillic acidHomovanillic AcidMiddle AgedMagnetic Resonance ImagingPsychiatry and Mental healthMonoamine neurotransmitterEndocrinologyFallypridechemistryPositron-Emission TomographyBenzamidesSchizophreniaQuetiapine34-Dihydroxyphenylacetic Acidbusinessmedicine.drugAntipsychotic AgentsProtein BindingJournal of psychiatric research
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Postoperative pain therapy after lumbar disc surgery.

2000

Object. This study was undertaken to determine whether a special postoperative pain administration of tramadol and diclofenac provides any benefits in patients who underwent microsurgical lumbar discectomy.  Methods. The study consisted of 60 patients undergoing microsurgical lumbar discectomy. Patients were randomly divided into two groups based on the postoperative pain management: 1) Group A (n=30): no standardized pain therapy; these patients received on demand different analgesics and at variable dosages which were selected by the neurosurgeons; 2) Group B (n=30): standardized pain therapy with specific dosages of tramadol and diclofenac in regular time intervals during the first 48 ho…

AdultMalemedicine.medical_specialtyDiclofenacAnalgesicPainLumbar vertebraeDiclofenacPostoperative ComplicationsmedicineHumansHerniaIntervertebral DiscTramadolAgedPain MeasurementLumbar Vertebraemedicine.diagnostic_testbusiness.industryAnti-Inflammatory Agents Non-SteroidalInterventional radiologyMiddle Agedmedicine.diseaseSurgeryAnalgesics OpioidIntervertebral diskmedicine.anatomical_structureAnesthesiaSurgeryDrug Therapy CombinationFemaleNeurology (clinical)TramadolComplicationbusinessmedicine.drugDiskectomyActa neurochirurgica
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