Search results for " region"

Conservation status of the Italian flora under the 92/43/EEC ‘Habitats’ Directive

2021

The results of the 4th National Report for the Italian flora under the 92/43/EEC ‘Habitats’ Directive are presented. The outcomes showed a general negative conservation status for plant species, with the worst situation being in the Mediterranean bioregion. At the National level, significant monitoring and conservation activities are required.

In-depth characterization of denitrifier communities across different soil ecosystems in the tundra

2022

Abstract Background In contrast to earlier assumptions, there is now mounting evidence for the role of tundra soils as important sources of the greenhouse gas nitrous oxide (N2O). However, the microorganisms involved in the cycling of N2O in this system remain largely uncharacterized. Since tundra soils are variable sources and sinks of N2O, we aimed at investigating differences in community structure across different soil ecosystems in the tundra. Results We analysed 1.4 Tb of metagenomic data from soils in northern Finland covering a range of ecosystems from dry upland soils to water-logged fens and obtained 796 manually binned and curated metagenome-assembled genomes (MAGs). We then sear…

Ultraviolet A1 radiation induces nitric oxide synthase-2 expression in human skin endothelial cells in the absence of proinflammatory cytokines.

2001

Skin exposure to ultraviolet radiation from sunlight causes erythema and edema formation as well as inflammatory responses. As some of these ultraviolet-induced effects are potentially mediated by nitric oxide synthases, we examined the role of cytokines and ultraviolet A 1 radiation (340–400 nm) on the expression of the nitric oxide synthase-2 in endothelia of normal human skin biopsies during short-term organ culture as well as expression and activity of the nitric oxide synthase-2 in in vitro cell cultures of human dermal endothelial cells. Both, cytokine challenge (interleukin-1β + tumor necrosis factor-α + interferon-γ) but also ultraviolet A 1 exposure (50 J per cm 2 ) in the absence …

Zīdaiņu mirstības atšķirības Baltijas reģionā - Latvijā, Igaunijā, Lietuvā saistībā ar makroekonomiskajiem faktoriem no 2010. līdz 2016. gadam

2020

Tēmas pamatojums: Zīdaiņu un bērnu līdz 5 mirstība ir viens no galvenajiem valstu un bērnu labklājības rādītājiem, kas joprojām ir augsti pat vairākās attīstītās valstīs. Šī iemesla dēļ ir svarīgi monitorēt veicinošos faktorus, kas rada bērnu mirstības riskus agrīnā vecumā reģionālā perspektīvā, lai varētu tos mazināt un novērst. i,. Pētījumu sērija, ko veica LU MF Pediatrijas katedra Valsts pētījumu programmas ietvaros (1996 – 2010), identificēja cēloņsakarības starp bērnu mirstību un atsevišķiem socio- un makro-ekonomiskiem faktoriem Baltijas valstīs un atklāja atšķirības to savstarpējā mijiedarbā Latvijā, salīdzinājumā ar Lietuvu un Igauniju. MērķisMērķis bija konstatēt vai Baltijas reģi…

Deconstruction and hermeneutical space as keys to understanding the rural

2020

The purpose of this article is to complement the existing literature on defining the rural by suggesting a novel approach that makes possible a holistic understanding of the rural. The proposed approach is based on deconstruction of the concept of the rural and on hermeneutical philosophy. The current approaches applied in rural studies are evaluated through the lens of holistic understanding, and solutions to the observed problems are discussed. The problems of current rural studies stem from inadequate conceptualization and biased social theory. The conceptual problems can be alleviated, firstly, by understanding the concept of space not only literally but also figuratively. Secondly, the…

Towards the ‘rurban’ scenario: plural forms of planning in Europe for a new alliance between city and countryside - Verso lo scenario ‘rurban’: forme…

2015

Nell’ultimo decennio si è manifestata una crescente attenzione alle relazioni di interdipendenza tra di- mensione urbana e dimensione rurale dello sviluppo territoriale. È un interesse alimentato dalla diversa percezione con cui ormai viene colto il rapporto tra città e campagna, tra economie urbane ed economie rurali, considerate dal pensiero economico-politico classico come due mondi separati. Questo processo è particolarmente visibile nel con- testo europeo, dove per ragioni non solo insediative e funzionali, ma anche economiche, sociali e culturali l’avvento di modelli di sviluppo post-industriali ha portato a più complesse forme di ibridazione tra modelli di sviluppo urbani e rurali. L…

Il ri-ciclo socialmente innovativo come attivatore di sviluppo urbano e regionale. I brownfield come contesto di analisi e azione.

The research topic is the re-cycling of brownfields with social innovative practices, and how it can activate the urban and regional development. The research analyses critically and interprets the re-cycle theory (Marini and Bocchi 2014; Carta 2014) developed by the Italian Research “Re-cycle Italy” (PRIN) focusing on its social innovative aspects (Moulaert et al., 2005; Phills et al., 2008, Tekin and Tekdogan, 2015). Nowadays, the community-based planning is essential for the spatial regeneration processes. These realities generate a new sense of consciousness and a huge network of local activists, social enterprises able to develop the place in an incremental way. Therefore, it is import…

UD&EP – A project to plan and design European urban regions

2008

Regulation of type 1 fimbriae synthesis and biofilm formation by the transcriptional regulator LrhA of Escherichia coli

2005

Type 1 fimbriae ofEscherichia colifacilitate attachment to the host mucosa and promote biofilm formation on abiotic surfaces. The transcriptional regulator LrhA, which is known as a repressor of flagellar, motility and chemotaxis genes, regulates biofilm formation and expression of type 1 fimbriae. Whole-genome expression profiling revealed that inactivation oflrhAresults in an increased expression of structural components of type 1 fimbriae.In vitro, LrhA bound to the promoter regions of the twofimrecombinases (FimB and FimE) that catalyse the inversion of thefimApromoter, and to the invertible element itself. TranslationallacZfusions with these genes and quantification offimEtranscript le…

Properties of transmembrane helix TM1 of the DcuS sensor kinase of Escherichia coli, the stator for TM2 piston signaling

2021

Abstract The sensor kinase DcuS of Escherichia coli perceives extracellular fumarate by a periplasmic PASP sensor domain. Transmembrane (TM) helix TM2, present as TM2-TM2′ homo-dimer, transmits fumarate activation in a piston-slide across the membrane. The second TM helix of DcuS, TM1, is known to lack piston movement. Structural and functional properties of TM1 were analyzed. Oxidative Cys-crosslinking (CL) revealed homo-dimerization of TM1 over the complete membrane, but only the central part showed α-helical +3/+4 spacing of the CL maxima. The GALLEX bacterial two-hybrid system indicates TM1/TM1′ interaction, and the presence of a TM1-TM1′ homo-dimer is suggested. The peripheral TM1 regi…