Search results for " rev"

showing 10 items of 3376 documents

Editorial Judgments

2009

Based on participant observation of editors’ decisions for a sociology journal, the paper investigates the peer review process. It shows a hidden interactivity in peer review, which is overlooked both by authors who impute social causes to unwelcome decisions, and by the preoccupation with ‘reliability’ prevalent in peer review research. This study shows that editorial judgments are: (1) attitudes taken by editorial readers toward various kinds of text, as a result of their membership in an intellectual milieu; (2) impressions gained through the reading process (through a ‘virtual interaction’ with the author); and (3) rationalizing statements about manuscripts made by editors and addressed…

Historymedia_common.quotation_subjectGeneral Social SciencesParticipant observationPraxeologyPeer reviewEpistemologyInteractivityHistory and Philosophy of ScienceInformal communicationVotingSociologyDecision processSocial psychologymedia_commonSocial Studies of Science
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The Artistic Commitment of Kenyon Cox: An American Neoclassical Artist

2016

At the end of the nineteenth century, the United States had undergone deep transformations. The second Industrial Revolution had created huge amounts of new wealth and power. This led to an alteration of the urban social fabric and to a repositioning of the country on the international scene.Since the 1870s, the American Renaissance had been a vehicle for the diffusion of new values and new concepts. As a broad neoclassical movement in the arts, it was committed to a rewriting of the country’s national past.At the time, Kenyon Cox (1856-1919) distinguished himself as one of the major artists of the movement, but also as one of its most influential critics and theorists. Cox developed theori…

Historymedia_common.quotation_subjectSecond Industrial Revolutionclassicismevolution(ism)The artsVisual arts[SHS]Humanities and Social SciencesPower (social and political)anti-modernisme[ SHS ] Humanities and Social Sciencesévolutionnismelcsh:Social sciences (General)évolutionclassicismeComputingMilieux_MISCELLANEOUSmedia_commonEnthusiasmPaintinglcsh:English languageKenyon CoxThe RenaissanceSpanish Civil WarCox - Classicism - FormalismKenyon Cox + Neoclassicismantimodernismlcsh:H1-99[SHS] Humanities and Social Scienceslcsh:PE1-3729Classicism
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Print and online newspapers as material artefacts

2014

Traditional newspaper journalism is in a state of crisis and there have been several attempts to overcome this. Many discourses have reiterated the triumphal march of a digital revolution in newspaper journalism and anticipated the end of the print newspaper. This moment calls for an in-depth analysis of reader habits of news consumption and use in order to understand the audiences for journalistic output and their relationship with the journalistic objects. In this study, we adopt a multi-method approach, integrating (1) qualitative content analysis of student essays dealing with the physicality of printed and online newspapers, (2) ethnographic observation of the use practices of readers…

Historymedia_common.quotation_subjectritualizationemotioncomputer.software_genrereadershipNewspaperprint newspaperArts and Humanities (miscellaneous)State (polity)eleetonline newspaperRitualizationta518use practicesmedia_commonMultimediaCommunicationgesturesMedia studiesta5142posturesAudience measurementComputingMethodologies_DOCUMENTANDTEXTPROCESSINGJournalismEmotion; gestures; material objects; online newspaper; postures; print newspaper; readership; ritualization; use practicesDigital Revolutioncomputermaterial objectsGestureJournalism
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Innenrücktitelbild: Structure-Based Design of an RNA-Bindingp-Terphenylene Scaffold that Inhibits HIV-1 Rev Protein Function (Angew. Chem. 50/2013)

2013

Hiv 1 revProtein functionScaffoldStereochemistryChemistryPolymer chemistryHuman immunodeficiency virus (HIV)medicineStructure basedRNAGeneral Medicinemedicine.disease_causeAngewandte Chemie
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Structure-Based Design of an RNA-Bindingp-Terphenylene Scaffold that Inhibits HIV-1 Rev Protein Function

2013

Hiv 1 revScaffoldAnti-HIV AgentsStereochemistryHuman immunodeficiency virus (HIV)Virus Replicationmedicine.disease_causeCatalysisStructure-Activity RelationshipTerphenyl CompoundsmedicineHumansProtein functionBinding SitesDose-Response Relationship DrugMolecular StructureChemistryRNArev Gene Products Human Immunodeficiency VirusGeneral MedicineGeneral ChemistrySmall moleculeDrug DesignHIV-1RNAStructure basedAngewandte Chemie International Edition
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Inside Back Cover: Structure-Based Design of an RNA-Bindingp-Terphenylene Scaffold that Inhibits HIV-1 Rev Protein Function (Angew. Chem. Int. Ed. 50…

2013

Hiv 1 revScaffoldProtein functionStereochemistryChemistryINTStructure basedRNACover (algebra)General ChemistryCombinatorial chemistrySmall moleculeCatalysisAngewandte Chemie International Edition
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Arylpyridines, arylpyrimidines and related compounds as potential modulator agents of the VEGF, hTERT and c-Myc oncogenes.

2019

Twenty-four derivatives structurally related to honokiol have been synthesized and biologically evaluated. IC50 values were determined towards the HT-29, MCF-7 and HEK-293 cell lines. Some of these derivatives exhibited comparable or lower IC50 values than honokiol towards the HT-29 and MCF-7 cell lines or else higher selectivity indexes than the natural product. Twelve selected derivatives were evaluated for their ability to inhibit the expression of the VEGFA, hTERT and c-Myc genes and also to inhibit the production of total c-Myc protein and the secretion of the VEGF protein. One of the most promising compounds, 3-(2,4-dimethoxyphenyl)pyridine, may be a good candidate for further studies…

Honokiolantiproliferative activityVascular Endothelial Growth Factor APyridinesClinical Biochemistryaza and diazabiphenyl derivativesPharmaceutical ScienceDown-RegulationGene ExpressionAntineoplastic Agents01 natural sciencesBiochemistrygene targetingProto-Oncogene Proteins c-mycchemistry.chemical_compoundanticancer agentsCell Line TumorDrug DiscoveryGene expressionHumansSecretionTelomerase reverse transcriptaseMolecular BiologyTelomeraseCell ProliferationNatural product010405 organic chemistryOrganic ChemistryGene targeting0104 chemical sciences010404 medicinal & biomolecular chemistryVascular endothelial growth factor AHEK293 CellsPyrimidineschemistryCell cultureProtein BiosynthesisCancer researchMolecular MedicineBioorganicmedicinal chemistry
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The intestinal 3M (microbiota, metabolism, metabolome) zeitgeist – from fundamentals to future challenges

2021

The role of the intestine in human health and disease has historically been neglected and was mostly attributed to digestive and absorptive functions. In the past two decades, however, discoveries related to human nutrition and intestinal host-microbe reciprocal interaction have established the essential role of intestinal health in the pathogenesis of chronic diseases and the overall wellbeing. That transfer of gut microbiota could be a means of disease phenotype transfer has revolutionized our understanding of chronic disease pathogenesis. This narrative review highlights the major concepts related to intestinal microbiota, metabolism, and metabolome (3M) that have facilitated our fundame…

Host Microbial InteractionsbiologyMicrobiotaDiseaseGut florabiology.organism_classificationBioinformaticsBiochemistryGastrointestinal MicrobiomeIntestinesHuman healthChronic diseasePhysiology (medical)MetabolomeMetabolomeHumansNarrative reviewDietary PhytochemicalsZeitgeistFree Radical Biology and Medicine
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Democrazia deliberativa e Convenzione europea dei diritti umani

2010

Deliberative democracy and the European Convention on Human Rights Theories of deliberative democracy have rapidly become very popular amongst political scientists. The central argument of these theories is that democratic legitimacy of lawmaking does not lie (or does not only lie) in the elected character of Parliaments but in public delib- eration processes. Decisions have to be justified by reasons and reasons have to be publicly debated. Legitimacy also depends on the opportunity for citizens to participate effectively in public debates. In this paper I argue that the European Court of Human Rights can be a key player in promoting a democracy based on public deliberation and that in the…

Human rightsDemocrazia deliberativa - Convenzione europea dei diritti umani - Libertà di espressione - Necessità in una società democraticaJudicial reviewmedia_common.quotation_subjectDeliberationDemocracyRepresentative democracyDeliberative democracyLawPolitical scienceSettore IUS/13 - Diritto InternazionaleMargin of appreciationDeliberative democracy - European Convention on Human Rights - Freedom of Expression - Necessity in a democratic societyLegitimacymedia_common
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The Ambivalently Good Human Rights

2016

Human rightsGeneral Chemical Engineeringmedia_common.quotation_subjectkansainvälinen politiikkabook reviewslcsh:JC11-607lcsh:Women. Feminismhuman rightslcsh:Political theoryihmisoikeuspolitiikkaihmisoikeudetkirja-arvosteluthuman rights policyPolitical scienceLawinternational politicsta517lcsh:HQ1101-2030.7media_commonRedescriptions : Political Thought, Conceptual History and Feminist Theory
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