Search results for " sigma"
showing 10 items of 76 documents
A Study on Different Approaches of Six-Sigma and Knowledge Management Integrated Models to Identify the Leveraging Effects
2014
Abstract The purpose of this paper is to review the different models which integrate Six Sigma and Knowledge Management (KM) approaches and also to identify the advantages and disadvantages of those models. Based on literature, the available Six Sigma and KM models have been reviewed. All the models have been critically analysed according to their structure and end users and finally the advantages and disadvantages are enlisted. The Overview expressed that more or less every model has been proposed aiming to the specific endues and each model has both strength and weakness for application to all sectors. In this article, the advantages and disadvantages of existing Six Sigma-KM models have …
KPD: An Investigation into the Usability of Knowledge Portal in DMAIC Knowledge Management
2016
Knowledge is considered as a resource that contributes an important role in the success of Six Sigma DMAIC methodology. However, knowledge resides brain of the individuals and exists in various forms and different places. This rise the problem of how to collect and share DMAIC knowledge everywhere all time. In this paper, we introduce a proposed Knowledge Portal named KPD that had been designed as a tool to manage DMAIC knowledge. Through the deployment of the Knowledge Portal, this paper aims at investigating its impacts on DMAIC execution based on experiments and appreciation of experts who are working in the areas of quality management and information technology. The results of the surve…
The cognition‐enhancing activity of E1R , a novel positive allosteric modulator of sigma‐1 receptors
2013
Background and Purpose Here, we describe the in vitro and in vivo effects of (4R,5S)-2-(5-methyl-2-oxo-4-phenyl-pyrrolidin-1-yl)-acetamide (E1R), a novel positive allosteric modulator of sigma-1 receptors. Experimental Approach E1R was tested for sigma receptor binding activity in a [3H](+)-pentazocine assay, in bradykinin (BK)-induced intracellular Ca2+ concentration ([Ca2+]i) assays and in an electrically stimulated rat vas deferens model. E1R's effects on cognitive function were tested using passive avoidance (PA) and Y-maze tests in mice. A selective sigma-1 receptor antagonist (NE-100), was used to study the involvement of the sigma-1 receptor in the effects of E1R. The open-field test…
3D-Chiral quadratic indices of the ‘molecular pseudograph’s atom adjacency matrix’ and their application to central chirality codification: classific…
2004
Quadratic indices of the 'molecular pseudograph's atom adjacency matrix' have been generalized to codify chemical structure information for chiral drugs. These 3D-chiral quadratic indices make use of a trigonometric 3D-chirality correction factor. These indices are nonsymmetric and reduced to classical (2D) descriptors when symmetry is not codified. By this reason, it is expected that they will be useful to predict symmetry-dependent properties. 3D-Chirality quadratic indices are real numbers and thus, can be easily calculated in TOMOCOMD-CARDD software. These descriptors circumvent the inability of conventional 2D quadratic indices (Molecules 2003, 8, 687-726. http://www.mdpi.org) and othe…
Atom-based Stochastic and non-Stochastic 3D-Chiral Bilinear Indices and their Applications to Central Chirality Codification
2006
Abstract Non-stochastic and stochastic 2D bilinear indices have been generalized to codify chemical structure information for chiral drugs, making use of a trigonometric 3D-chirality correction factor. In order to evaluate the effectiveness of this novel approach in drug design we have modeled the angiotensin-converting enzyme inhibitory activity of perindoprilate's σ-stereoisomers combinatorial library. Two linear discriminant analysis models, using non-stochastic and stochastic linear indices, were obtained. The models had shown an accuracy of 95.65% for the training set and 100% for the external prediction set. Next the prediction of the σ-receptor antagonists of chiral 3-(3-hydroxypheny…
The radiative decay of the Lambda(1405) and its two-pole structure
2007
We evaluate theoretically the radiative decay widths into $\gamma\Lambda$ and $\gamma\Sigma^0$ of the two poles of the $\Lambda(1405)$ found in chiral unitary theories and we find quite different results for each of the two poles. We show that, depending on which reaction is used to measure the $\Lambda(1405)$ radiative decays, one gives more weight to one or the other pole, resulting in quite different shapes in the $\gamma\Lambda(\Sigma^0)$ invariant mass distributions. Our results for the high-energy pole agree with those of the empirical determination of the $\gamma\Lambda$ and $\gamma\Sigma^0$ radiative widths (based on an isobar model fitting of the $K^-p$ atom data), which are someti…
Measurements of Sigma(+) and Sigma(-) time-like electromagnetic form factors for center-of-mass energies from 2.3864 to 3.0200 GeV
2021
Physics letters / B 814, 136110 (2021). doi:10.1016/j.physletb.2021.136110
"Table 2" of "Investigation of the p-$\Sigma^{0}$ interaction via femtoscopy in pp collisions"
2020
Measured correlation function of p$-\Sigma^{0}$p $\oplus$ $\overline{\mathrm{p}}-\overline{\Sigma^{0}}$
"Table 1" of "Measurement of the polarization of Lambda0, anti-Lambda0, Sigma+ and Xi- produced in a Sigma- beam of 330-GeV/c"
1995
Target Consisted of a copper and a carbon block arranged side by side.
"K0S0_dcs02" of "$K^+\Lambda$ and $K^+\Sigma^0$ photoproduction with fine center-of-mass energy resolution"
2022
Excitation function at cos(Theta_K+)cm = -0.7