Search results for " stratification"

Risk Stratification by nrTMS Language Mapping

2017

Resecting language-eloquent brain lesions is a major challenge in neurosurgery since we need to weight the risks of worsening the patients’ functional integrity and achieving a maximum safe resection. Although relevant functional brain structures can be identified intraoperatively by direct cortical mapping during awake surgery, a preoperative identification of functional anatomy is recommended in order to gauge surgical risks, evaluate resectability, plan the surgical approach, and identify potential starting points for intraoperative stimulation mapping.

Risk stratification of normotensive pulmonary embolism based on the sPESI — Does it work for all patients?

2015

P6456Neopterin for risk stratification of patients with acute chest pain

2018

Response to Letter Regarding Article, “The Inflammatory Hypothesis: Any Progress in Risk Stratification and Therapeutic Targets?”

2007

We thank Drs Ridker and Everett for their interest in our work,1 and we commend Ridker’s pioneering work describing an association between C-reactive protein (CRP) and the risk of myocardial infarction or stroke. Subsequent studies have both confirmed and refuted these original observations. The former studies “controlled” or “adjusted” for fewer other risk factors; when they did so, they dichotomized variables (a weaker approach) rather than using them as continuous variables. By contrast, the latter studies have incorporated adjustments for other markers (especially of abdominal obesity, because visceral fat …

Treatment of patients with essential hypertension and microalbuminuria.

1998

There has been increasing interest in the question of whether microalbuminuria can be used in the risk stratification of patients with essential hypertension. A cluster of cardiovascular and/or renal risk factors may be associated with microalbuminuria in hypertension. Despite this, prospective data about the potential role of microalbuminuria as a prognostic marker of cardiovascular and/or renal risk have been sparse and inconclusive until now. Blood pressure values have been considered the most important determinant of microalbuminuria in essential hypertension; however, hyperinsulinaemia--a metabolic component-was noted to be present in conjunction with high blood pressure. Furthermore, …

Advances in detection and characterization of atherosclerosis using contrast agents targeting the macrophage

2006

With advances in imaging technology and our understanding of the role of inflammation in atherosclerosis, the macrophage appears to be an excellent target for imaging the progression of disease. In addition to imaging the macrophage with only 1 modality, contrast agents can be created that can be imaged with multiple modalities. This seems extremely attractive, as lesion morphology and characteristics can be determined with modalities that provide high picture resolution, such as CT or MRI, whereas macrophage quantity can be accurately determined through the creation of a radiolabeled contrast agent such as FDG via PET. Although this combination of imaging technologies may yield clinically …

Hemithyroidectomy versus total thyroidectomy in the intermediate-risk differentiated thyroid cancer: the Italian Societies of Endocrine Surgeons and …

2021

The surgical treatment of the intermediate-risk DTC (1–4 cm) remains still controversial. We analyzed the current practice in Italy regarding the surgical management of intermediate-risk unilateral DTC to evaluate risk factors for recurrence and to identify a group of patients to whom propose a total thyroidectomy (TT) vs. hemithyroidectomy (HT). Among 1896 patients operated for thyroid cancer between January 2017 and December 2019, we evaluated 564 (29.7%) patients with unilateral intermediate-risk DTC (1–4 cm) without contralateral nodular lesions on the preoperative exams, chronic autoimmune thyroiditis, familiarity or radiance exposure. Data were collected retrospectively from the clini…

Pulmonary Embolism: Contemporary Medical Management and Future Perspectives

2018

Pulmonary embolism (PE) contributes substantially to the global disease burden. A key determinant of early adverse outcomes is the presence (and severity) of right ventricular dysfunction. Consequently, risk-adapted management strategies continue to evolve, tailoring acute treatment to the patients' clinical presentation, hemodynamic status, imaging and biochemical markers, and comorbidity. For subjects with hemodynamic instability or 'high-risk' PE, immediate systemic reperfusion treatment with intravenous thrombolysis is indicated; emerging approaches such as catheter-directed pharmacomechanical reperfusion might help to minimize the bleeding risk. Currently, direct, non-vitamin K-depende…

Una nota sobre crisis y estratificación social

2012

La crisis actual ha creado un colectivo específico de personas en riesgo de caer en la exclusión social. Básicamente se trata de jóvenes e inmigrantes. En ambos casos se agrava cuando coincide con escasa formación y cargas familiares. Su futuro es más que incierto y cabe predecir que la sociedad tardará en encontrarles acomodo pues ni el actual modelo productivo, ni el que pueda sustituirlo, van a generar empleo para esos perfiles. Pero es que tampoco el actual modelo de protección social, lento en sus reacciones y sesgado en favor de currícula laborales estables y continuados, les dará cobertura suficiente. La E.P.A. nos permite una aproximación al problema desde el ejemplo de la Comunidad…

Możliwości i potrzeby edukacyjne skazanych poszkodowanych w więziennej rzeczywistości

2018

Skazani poszkodowani - pod względem funkcjonowania w zakładzie karnym - reprezentują specyficzną grupę osadzonych. Tekst w całości poświęcony jest kategorii osób, którzy w środowisku więziennym są napiętnowani przez współosadzonych. Izolacja od potencjalnych oprawców skłania kadrę do prowadzenia oddziaływań penitencjarnych - w tym także i edukacyjnych - odrębnie od pozostałej społeczności inkarcerowanej. Istotne wydaje się więc, w jaki sposób ich sytuacja społeczna (izolacja od pozostałych więźniów) oraz psychologiczna (degradacja poprzez wykluczenie) determinuje aktywność edukacyjną w instytucji totalnej, jaką jest więzienie. W tekście uwagę zwrócono zarówno na edukacji formalnej (szkoła),…