Search results for " translatio"
showing 10 items of 503 documents
Outline for a Relevance Theoretical Model of Machine Translation Post-editing
2018
Translation process research (TPR) has advanced in the recent years to a state which allows us to study “in great detail what source and target text units are being processed, at a given point in time, to investigate what steps are involved in this process, what segments are read and aligned and how this whole process is monitored” (Alves 2015, p. 32). We have sophisticated statistical methods and with the powerful tools to produce a better and more detailed understanding of the underlying cognitive processes that are involved in translation. Following Jakobsen (2011), who suspects that we may soon be in a situation which allows us to develop a computational model of human translation, Alve…
Monolingual and cross-lingual intent detection without training data in target languages
2021
Due to recent DNN advancements, many NLP problems can be effectively solved using transformer-based models and supervised data. Unfortunately, such data is not available in some languages. This research is based on assumptions that (1) training data can be obtained by the machine translating it from another language
Dal martire al cacciatore. Traduzioni intersemiotiche dell’eroismo antimafia
2022
Questo contributo muove da un'analisi comparativa tra la biografia di Alfonso Sabella "Cacciatore di mafiosi" (Mondadori, 2008) e le prime due stagioni della fiction Rai "Il Cacciatore" (2018-2020), tratte dal libro. L'obbiettivo è problematizzare questo processo di traduzione intersemiotica alla luce dell'evoluzione dei modelli d'eroismo dei personaggi. Nel saggio, ricolleghiamo questa evoluzione a una riflessione più generale sulla natura transmediale della memoria collettiva, sempre più legata allo spettacolo del passato costruito dai media, che ibridano tra loro generi diversi. Per situare le tendenze contemporanee della memoria dell'eroismo antimafia all'interno di una genealogia pià a…
Translating intracarotid artery transplantation of bone marrow-derived NCS-01 cells for ischemic stroke: Behavioral and histological readouts and mec…
2019
Abstract The present study used in vitro and in vivo stroke models to demonstrate the safety, efficacy, and mechanism of action of adult human bone marrow‐derived NCS‐01 cells. Coculture with NCS‐01 cells protected primary rat cortical cells or human neural progenitor cells from oxygen glucose deprivation. Adult rats that were subjected to middle cerebral artery occlusion, transiently or permanently, and subsequently received intracarotid artery or intravenous transplants of NCS‐01 cells displayed dose‐dependent improvements in motor and neurological behaviors, and reductions in infarct area and peri‐infarct cell loss, much better than intravenous administration. The optimal dose was 7.5 × …
Genome-wide Analyses Identify KIF5A as a Novel ALS Gene
2018
© 2018 Elsevier Inc.
Can the TLR-4-mediated signaling pathway be "a key inflammatory promoter for sporadic TAA"?
2014
Thoracic aorta shows with advancing age various changes and a progressive deterioration in structure and function. As a result, vascular remodeling (VR) and medial degeneration (MD) occur as pathological entities responsible principally for the sporadic TAA onset. Little is known about their genetic, molecular, and cellular mechanisms. Recent evidence is proposing the strong role of a chronic immune/inflammatory process in their evocation and progression. Thus, we evaluated the potential role of Toll like receptor- (TLR-) 4-mediated signaling pathway and its polymorphisms in sporadic TAA. Genetic, immunohistochemical, and biochemical analyses were assessed. Interestingly, the rs4986790 TLR4…
Attenuation of disease phenotype through alternative translation initiation in low-penetrance retinoblastoma
2006
Hereditary predisposition to retinoblastoma (RB) is caused by germline mutations in the retinoblastoma 1 (RB1) gene and transmits as an autosomal dominant trait. In the majority of cases disease develops in greater than 90% of carriers. However, reduced penetrance with a large portion of disease-free carrier is seen in some families. Unambiguous identification of the predisposing mutation in these families is important for accurate risk prediction in relatives and their genetic counseling but also provides conceptual information regarding the relationship between the RB1 genotype and the disease phenotype. In this study we report a novel mutation detected in 10 individuals of an extended fa…
Results from Finland’s 2014 Report Card on Physical Activity for Children and Youth
2014
The Finnish 2014 Report Card on Physical Activity (PA) for Children and Youth is the first assessment of Finland’s efforts in promoting and facilitating PA opportunities for children and youth using the Active Healthy Kids Canada grading system. The Report Card relies primarily on research findings from 6 Research Institutes, coordinated by the University of Jyväskylä. The Research Work Group convened to evaluate the aggregated evidence and assign grades for each of the 9 PA indicators, following the Canadian Report Card protocol. Grades from A (highest) to F (lowest) varied in Finland as follows: 1) Overall physical activity—fulfillment of recommendations (D), 2) Organized sport participat…
A translational paradigm to dtudy the rffects of uncontrollable stress in humans
2020
Theories on the aetiology of depression in humans are intimately linked to animal research on stressor controllability effects. However, explicit translations of established animal designs are lacking. In two consecutive studies, we developed a translational paradigm to study stressor controllability effects in humans. In the first study, we compared three groups of participants, one exposed to escapable stress, one yoked inescapable stress group, and a control group not exposed to stress. Although group differences indicated successful stress induction, the manipulation failed to differentiate groups according to controllability. In the second study, we employed an improved paradigm and co…
A comparative evaluation of NB30, NB54 and PTC124 in translational read-through efficacy for treatment of an USH1C nonsense mutation
2012
Translational read-through-inducing drugs (TRIDs) promote read-through of nonsense mutations, placing them in the spotlight of current gene-based therapeutic research. Here, we compare for the first time the relative efficacies of new-generation aminoglycosides NB30, NB54 and the chemical compound PTC124 on retinal toxicity and read-through efficacy of a nonsense mutation in the USH1C gene, which encodes the scaffold protein harmonin. This mutation causes the human Usher syndrome, the most common form of inherited deaf-blindness. We quantify read-through efficacy of the TRIDs in cell culture and show the restoration of harmonin function. We do not observe significant differences in the read…