Search results for " value"

Synthesis and biological evaluation of novel peptidomimetics as rhodesain inhibitors

2016

Novel rhodesain inhibitors were developed by combining an enantiomerically pure 3-bromoisoxazoline warhead with a 1,4-benzodiazepine scaffold as specific recognition moiety. All compounds were proven to inhibit rhodesain with Ki values in the low-micromolar range. Their activity towards rhodesain was found to be coupled to an in vitro antitrypanosomal activity, with IC50 values ranging from the mid-micromolar to a low-micromolar value for the most active rhodesain inhibitor (R,S,S)-3. All compounds showed a good selectivity against the target enzyme since all of them were proven to be poor inhibitors of human cathepsin L. Novel rhodesain inhibitors were developed by combining an enantiomeri…

Casual, Colloquial, Commonsensical: A News Values Stylistic Analysis of a Populist Newsfeed

2021

This study explores a mediated variety of right-wing populist discourse in the digital context, given the populists’ inclination to bypass legacy media to connect directly to the citizens to garner political support. It analyzes a sample of the Tea Party’s newsfeed headlines posted in the spring of 2019. A corpus of 308 headlines collected according to a “constructed week” formula has been coded first according to selected news values parameters (Bednarek and Caple 2017), and then with respect to stylistic devices operationalized in terms of “casual,” “colloquial” and “commonsensical” expressions. Methodologically, the study aims to combine the perspectives of newsworthiness and stylistics …

Mixing pop and politics : a study of political pop music in Britain in the 1980s

2000

L'interaction lieu – objet comme modélisation de l'expérience culturelle vécue : définition, mesure et validation empirique dans le cas du spectacle …

2006

This article proposes to reconsider the concept of lived cultural experience. In a first part, we explore the track of value. We try to justify of its interest to apprehend the experience. We also seek to improve the conceptualization of the experience by defining it as an interaction place - object. Then, in a second part, we present an empirical test of this conceptualization in the field of lives performance. This test is followed of a discussion about the results.

Conceptualisation et mesure de la valeur perçue d'un lieu de consommation. Application au domaine du spectacle vivant

2005

This article seeks to understand the role of a place during a consumption experience. We explore the track of value and present a scale of perceived value of a place. In this way, we have done a state of art about the value and we justify for using this concept to grasp the physical environment. We present the stages of the scale's building.

Constructing a “breakthrough”: News values in Science Magazine's 2017 ranking of most important discoveries

2018

The objective of this study is to conduct a stylistic analysis of the synopses publicized in the end-of-the-year ranking list of 2017 scientific “breakthroughs” from Science Magazine. The article provides a review of literature on science popularization (also known as science accommodation) and presents the typology of news values and rationalization cues that are used by editors to make science-related coverage both newsworthy and credible at the same time. The article lists the possible ways in which scientific findings can be stylistically constructed as “breakthroughs”. The analysis consists in quantifying and illustrating the typical stylistic maneuvers for framing selected science-rel…

Developing and comparing methods for mapping habitat types and conservation values using remote sensing data and GIS methods

2014

Inny/obcy: doświadczenie języka i rzeczywistości (literacko-kulturowa ponowoczesność)

2017

The subject matter is developed around the Other, their presence and their personalising in the literary-cultural space. The reality becomes the source of observation (fiction and non-fiction) and reveals not only a variety of human experience in the world of multiculturalism, but also forms of “branding” the Other (rhetoric of the dominant communities towards cultural minorities) which correspond to them. The analysis of the rhetoric of speech and image permits to reveal the good and the bad side of language-cultural stereotypes, including also attitudes and behaviours affected by ideology.

Singular (p, q)-equations with superlinear reaction and concave boundary condition

2020

We consider a parametric nonlinear elliptic problem driven by the sum of a p-Laplacian and of a q-Laplacian (a (Formula presented.) -equation) with a singular and (Formula presented.) -superlinear reaction and a Robin boundary condition with (Formula presented.) -sublinear boundary term (Formula presented.). So, the problem has the combined effects of singular, concave and convex terms. We look for positive solutions and prove a bifurcation-type theorem describing the changes in the set of positive solutions as the parameter varies.

Judo as a tool for social integration in adolescents at risk of social exclusion: A pilot study

2020

Purpose: Social policies of the advanced countries have begun to incorporate sport to speak on manifestations of social exclusion, as tool to reach out to young people, strengthen their identity or enhance self-esteem vulnerable groups. Judo can be a good tool for the fulfilment of this purpose because has a philosophy and educational practice that contains much of the core competencies of the educational system. The aim of this study is to analyse the incidence of judo practice in changing attitudes, values, norms and capabilities across organizational forms as a means of enhancing socialization in their interventions with young people at risk of social exclusion. Material/Methods: We used…