Search results for "-n"

showing 10 items of 5782 documents

Large-scale genotyping identifies 41 new loci associated with breast cancer risk

2013

Journal article Breast cancer is the most common cancer among women. Common variants at 27 loci have been identified as associated with susceptibility to breast cancer, and these account for ~9% of the familial risk of the disease. We report here a meta-analysis of 9 genome-wide association studies, including 10,052 breast cancer cases and 12,575 controls of European ancestry, from which we selected 29,807 SNPs for further genotyping. These SNPs were genotyped in 45,290 cases and 41,880 controls of European ancestry from 41 studies in the Breast Cancer Association Consortium (BCAC). The SNPs were genotyped as part of a collaborative genotyping experiment involving four consortia (Collaborat…

signaling pathwayGenotypingGenotypeSingle-nucleotide polymorphismGenome-wide association studyBreast NeoplasmsconsortiumBiologyBreast Neoplasms; Case-Control Studies; Cooperative Behavior; Female; Gene-Environment Interaction; Genetic Loci; Genome-Wide Association Study; Genotype; Humans; Meta-Analysis as Topic; Polymorphism Single Nucleotide; Risk Factors; Genetic Predisposition to Disease; GeneticsPolymorphism Single NucleotideArticle03 medical and health sciences0302 clinical medicineBreast cancerSDG 3 - Good Health and Well-beingMeta-Analysis as TopicRisk FactorsGenotypecommon variantsexpressionGeneticsmedicineHumansGenetic Predisposition to DiseasePolymorphismCooperative BehaviorgeneGenotypinghormone-related protein030304 developmental biologyGenetic associationGenetics0303 health sciencesBreast cancer susceptibilityCancerSingle Nucleotidemedicine.diseaseconfer susceptibilitysusceptibility loci3. Good health14q24.1 rad51l1TOX3Genetic Loci030220 oncology & carcinogenesisCase-Control Studiesgenome-wide associationFemaleGene-Environment InteractionGenome-Wide Association Study
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Optical hybrid nanocomposite sensors for selective explosive detection

2022

Durant l'última dècada, la detecció d'artefactes explosius improvisats (IEDs) tant en l'àmbit militar com civil s'ha convertit en una prioritat estratègica en la seguretat nacional a causa de la creixent amenaça terrorista. Encara que les tècniques convencionals, com la cromatografia de gasos acoblada a espectrometria de masses o la difracció de raigs X mostren notables avantatges degut a la seua elevada sensibilitat i selectivitat, una gran part d’aquestes presenten inconvenients, com per exemple processos de mesura lents, instrumentació cara, complexa i voluminosa, que limiten el mostreig en continu i en temps real. Per aquesta raó, existeix una recerca constant per trobar una plataforma …

silver nanoparticlesUNESCO::QUÍMICA::Química analítica::Espectroscopía de infrarrojosnanocompositeperovskite nanocrystalsUNESCO::QUÍMICA::Química inorgánicatemplate moleculequantum dotsmolecularly imprinted polymergas sensor3-nitrotoluenemultichannelsensorexplosive taggantlsprfluorescenceUNESCO::QUÍMICA::Química analítica::Análisis cromatográficoUNESCO::QUÍMICA::Química analítica::Espectroscopía de emisiónUNESCO::QUÍMICA::Química analítica::Análisis de polímeros
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Markova modeļu pielietojums notikumu vēstures pētīšanai

2020

Notikumu vēstures pētīšana ir iespējama ar vairākām metodēm, bet šajā darbā vairāk tiks apskatīta Markova modeļu pielietošana, sākot ar pirmo šādu modeli Neimaņa-Fiksa modeli un turpinot ar šobrīd aktuālajiem- divu stāvokļu modeli, konkurējošo risku modeli, slimības-nāves modeli. Vēl bez modeļiem tiks sniegta arī statistikas modeļu specifikācija un vairāki pielietojuma piemēri.

slimības-nāves modelisNeimaņa-Fiksa modelisMatemātikadivu stāvokļu modelisNotikumu vēstures pētīšanakonkurējošo risku modelis
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Ripensare gli oggetti, riprogettare la società

2021

The essay introduces a series of classical essays by Bruno Latour on design and techniques, showing the relationships between Actor Network Theory and semiotics. In particular, the theoretical convergences and problematic nodes on the methodological level concerning the application of certain semiotic notions, such as that of actant and that of enunciation, within Bruno Latour's anthropology are discussed.

sociosemiotics latour design objects actor-network theorySettore M-FIL/05 - Filosofia E Teoria Dei Linguaggi
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Can arbuscular mycorrhizal fungi enhance plant nitrogen capture from organic matter added to soil?

2012

soil proteinasesarbuscular mycorrhizal symbiosi15N-Nitrogen recoveryorganic matterSettore AGR/02 - Agronomia E Coltivazioni Erbacee
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Évolution urbaine d'un secteur de l'agglomération antique d'Intaranum : Entrains-sur-Nohain, 16 route d'Etais : rapport de fouille

2014

Cette opération a permis de comprendre l’organisation et l’évolution d’un quartier urbain de l’agglomération d’Intaranum sur les cinq premiers siècles de notre ère.Située immédiatement à l’est d’une voie reliant Entrains à Auxerre, la parcelle fouillée semble n’être investie que vers le début du Ier s. Les premiers indices d’occupation livrent l’image d’un paysage rural, peu anthropisé, centré chronologiquement sur la période augustéenne. La zone va bénéficier très rapidement de la mise en place d’une voie est-ouest, implantée de manière non perpendiculaire à l’axe principal, et qui semble polariser l’organisation générale du quartier. De part et d’autre, elle est équipée de portiques derri…

solurbanisme[SHS.ARCHEO]Humanities and Social Sciences/Archaeology and Prehistoryobjetvoiriepéristyle[SHS]Humanities and Social Sciencesatelierdallagejardinparcellaireédifice publicélément architecturalplacepuitsstatuairegallo-romainecaveEntrains-sur-Nohainlatrinesstructurescoriescéramique[SHS.ARCHEO] Humanities and Social Sciences/Archaeology and PrehistoryportiquefoyercaniveauAntiquité tardiveEmpire romainmétalliquemétallurgique[SHS] Humanities and Social Sciencesurbaine
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Shell-model computed cross sections for charged-current scattering of astrophysical neutrinos off 40Ar

2018

Charged-current (anti)neutrino-$^{40}\mathrm{Ar}$ cross sections for astrophysical neutrinos have been calculated. The initial and final nuclear states were calculated using the nuclear shell model. The folded solar-neutrino scattering cross section was found to be $1.78(23)\ifmmode\times\else\texttimes\fi{}{10}^{\ensuremath{-}42}\phantom{\rule{4pt}{0ex}}{\mathrm{cm}}^{2}$, which is higher than what the previous papers have reported. The contributions from the ${1}^{\ensuremath{-}}$ and ${2}^{\ensuremath{-}}$ multipoles were found to be significant at supernova-neutrino energies, confirming the random-phase approximation (RPA) result of a previous study. The effects of neutrino flavor conve…

solar radiationSHELL model01 natural sciencesdark matternucleus-neutrino interactionsNuclear physicspimeä aineCross section (physics)0103 physical sciences010306 general physicsauringonsäteilydark energyCharged currentPhysicsta114010308 nuclear & particles physicsScatteringNuclear shell modelneutriinotshell modelneutrinosDistribution (mathematics)solar neutrinosHigh Energy Physics::ExperimentNeutrinopimeä energiaParametrizationPhysical Review C
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Tailoring of the solid state properties of Al-Nb mixed oxides: A photoelectrochemical study

2013

Al-Nb containing mixed oxides were grown by anodizing sputter-deposited Al-Nb alloys of different compositions. A photoelectrochemical investigation was carried out in order to estimate the band gap, flat band potential, and conductivity type of these oxides as a function of their composition. The dependence of the band gap on the composition of mixed sp-d metal oxides has been rationalized by using a semiempirical correlation between the difference of electronegativity and band gap of oxides proposed in the literature some years ago and recently tested for regular d-d metal mixed oxides. The band gap increase observed as a function of Al content into the oxides seems mainly depending on th…

solid state properties Al-Nb mixed oxides photoelectrochemical studySettore ING-IND/23 - Chimica Fisica Applicata
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Elämä uusiksi : sopeutuminen sairastumisen tai vammautumisen aiheuttamaan elämänmuutokseen

2012

Tutkimukseni tarkoituksena on lisätä tietoa sopeutumisprosessista, jonka ihminen joutuu käymään läpi sairastuttuaan kroonisesti tai vammauduttuaan tapaturmassa niin, että seurauksena on pysyvä, fyysinen toimintarajoite. Nostan esille pysyvän toimintarajoitteen laaja-alaisen merkityksen sekä sen yksilölle asettamat, uudelleen määrittyvät tarpeet. Tarkastelen toimintarajoittuneisuuden merkitystä ihmiselle sekä yksilön näkökulmasta WHO:n mallin mukaisesti että ympäröivän yhteiskunnan näkökulmasta Oliverin sosiaalisen mallin mukaisesti. Teoreettisena perustana ovat sopeutumisprosessin eri vaiheet ensitiedon saamisesta identiteetin muutokseen. Sopeutumisprosessissa korostuu kokonaisvaltainen ihm…

sopeutuminentoimintarajoittuneisuussairastuminenkoko-naisvaltainen ihmiskäsitys ja identiteettiHaastattelututkimusvammautuminenidentiteettitoimintarajoitteetsopeutumisprosessiKvalitatiivinen tutkimusihmiskuva
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SparseHC: A Memory-efficient Online Hierarchical Clustering Algorithm

2014

Computing a hierarchical clustering of objects from a pairwise distance matrix is an important algorithmic kernel in computational science. Since the storage of this matrix requires quadratic space with respect to the number of objects, the design of memory-efficient approaches is of high importance to this research area. In this paper, we address this problem by presenting a memory-efficient online hierarchical clustering algorithm called SparseHC. SparseHC scans a sorted and possibly sparse distance matrix chunk-by-chunk. Meanwhile, a dendrogram is built by merging cluster pairs as and when the distance between them is determined to be the smallest among all remaining cluster pairs. The k…

sparse matrixClustering high-dimensional dataTheoretical computer scienceonline algorithmsComputer scienceSingle-linkage clusteringComplete-linkage clusteringNearest-neighbor chain algorithmConsensus clusteringmemory-efficient clusteringCluster analysisk-medians clusteringGeneral Environmental ScienceSparse matrix:Engineering::Computer science and engineering [DRNTU]k-medoidsDendrogramConstrained clusteringHierarchical clusteringDistance matrixCanopy clustering algorithmGeneral Earth and Planetary SciencesFLAME clusteringHierarchical clustering of networkshierarchical clusteringAlgorithmProcedia Computer Science
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