Search results for "14(59)"
showing 10 items of 19 documents
An overview of the molecular mechanisms underlying development and progression of bicuspid aortic valve disease
2019
Bicuspid aortic valve (BAV) is a common congenital heart malformation frequently associated with the development of aortic valve diseases and severe aortopathy, such as aortic dilatation, aneurysm and dissection. To date, different genetic loci have been identified in syndromic and non- syndromic forms of BAV. Among these, genes involved in the regulation of extracellular matrix remodelling, epithelial to mesenchymal transition and nitric oxide metabolism appear to be the main contributors to BAV pathogenesis. However, no- single gene model explains BAV inheritance, suggesting that more factors are simultaneously involved. In this regard, characteristic epigenetic and immunological profiles…
Measurement of Simplified Single- And Three-Phase Parameters for Harmonic Emission Assessment Based on IEEE 1459-2010
2021
This article investigates the feasibility of using a simplified approach, based on the measurement of power ratio parameters, for harmonic emissions assessment at the point of common coupling (PCC). The proposed approach comes from the common concept of power factor correction and the definitions of the IEEE Std. 1459-2010, where line utilization and harmonic pollution levels are evaluated by means of ratios between the power quantities of the apparent power decomposition. In addition to the IEEE Std. 1459–2010 indicators, in this article, the behavior is studied of additional parameters that are conceptually similar to those defined by the IEEE Std. 1459-2010. The suitability of such param…
A single-point strategy based on IEEE 1459-2000 for the Detection of Dominant Harmonic Sources in Power Systems
2008
This paper deals with a novel single-point strategy for the detection of harmonic sources in power systems. It is an enhancement of a previous strategy, developed by authors, which is based on the IEEE Std. 1459-2000 approach. In the paper, the effectiveness of the strategy is investigated, by means of simulation tests, which were carried out on a IEEE standard three-phase test power system. The analysis is carried out by considering also the presence of the measurement transducers.
Study, project and implementation of new metrics for distributed measurement system in medium voltage smart grid
2022
A DAQ-based sampling wattmeter for IEEE Std. 1459-2010 powers measurements. Uncertainty evaluation in nonsinusoidal conditions
2015
Abstract This paper presents the evaluation of the metrological performances of a DAQ-based sampling wattmeter (DAQ-SW) for the measurement of IEEE Std. 1459-2010 power quantities in non-sinusoidal conditions. The instrument makes use of two commercial data acquisition (DAQ) boards, a non-inductive current shunt, a personal computer and a commercial software for data processing. Starting from the results of an experimental characterization of the two instrument channels with non-sinusoidal voltages and currents and a correlation analysis, the combined standard uncertainties of IEEE Std. 1459-2010 quantities are evaluated, following the approach of the ISO Guide to the Expression of Uncertai…
A virtual instrument for the measurement of IEEE Std 1459-2000 power quantities
2006
In this paper, the authors present a PC-based instrument for the measurement of electrical-power quantities defined in IEEE Std. 1459. The instrument is based on a time-domain technique for the detection of the fundamental and harmonic components of voltages and currents. The time-domain strategy was originally developed by the authors for three-phase, three-wire systems. In that paper, the strategy had been extended to both three-phase, four-wire and single-phase systems. Simulation tests were carried out to assess the uncertainty contribution of the proposed strategy in the absence of the measurement transducers. Moreover, the accuracy of the PC-based instrument with its transducers was e…
A New Measurement Method for the Detection of Harmonic Sources in Power Systems Based on the Approach of the IEEE Std. 1459–2000
2010
In this paper, a novel single-point strategy is proposed for the detection of the harmonic sources in power systems. The method is an improvement of a strategy previously proposed by the authors; it is developed from the IEEE Std 1459-2000 approach and it can be entirely implemented in the time domain, thus simplifying the measurement system. The effectiveness of the proposed method is evaluated by introducing simple decision-making rules and by taking the presence of the measurement transducers into account. Several simulations and experimental tests are presented, showing that the enhanced strategy is able to give an useful information on the detection of the dominant harmonic source upst…
Un metodo single-point basato sulla IEEE 1459-2000 “effective apparent power resolution” per l’individuazione dei carichi disturbanti nei sistemi ele…
2009
A single-point approach based on nonactive power factor for the assessment of harmonic distortion sources in power systems
2022
This paper presents a study on the use of power factor indicators for the assessment of harmonic distortion sources in power systems. In detail the analysis is focused on the comparison between the proposed nonactive power factor (Q1/N) and the indicators of the IEEE Std. 1459-2010, and on the indicators feasibility in identifying the presence of harmonic distortion sources. As discussed in the paper, the proposed indicator can be evaluated with good accuracy, by means of typical power quantities measurements at the point of common coupling (PCC). Thus its measurement can be feasibly implemented in commercial platforms used for smart metering applications. To verify the proposal validity, s…
Murine tissue factor disulfide mutation causes a bleeding phenotype with sex specific organ pathology and lethality.
2019
Tissue factor is highly expressed in sub-endothelial tissue. The extracellular allosteric disulfide bond Cys186-Cys209 of human tissue factor shows high evolutionary conservation and in vitro evidence suggests that it significantly contributes to tissue factor procoagulant activity. To investigate the role of this allosteric disulfide bond in vivo, we generated a C213G mutant tissue factor mouse by replacing Cys213 of the corresponding disulfide Cys190-Cys213 in murine tissue factor. A bleeding phenotype was prominent in homozygous C213G tissue factor mice. Pre-natal lethality of 1/3rd of homozygous offspring was observed between E9.5 and E14.5 associated with placental hemorrhages. After b…