Search results for "1H"

showing 10 items of 1291 documents

The synthesis of metallocene-labelled drugs for biological assays

1990

Several drugs (amphetamine, desipramine, nortriptyline, phenobarbital) have been labelled with metallocenic fragments in order to develop a new immunoassay method. The metallocenic fragments are cymantrenic or benchrotrenic derivatives: the linkage between the organic and organometallic moieties has been achieved by reactions between amino and acidic functional groups. All the products (metallohaptens), purified by different chromatography techniques, have been fully characterized by IR and 1H NMR spectroscopy and their mass spectra.

1h nmr spectroscopyChromatographymedicine.diagnostic_testChemistryGeneral ChemistryChemical synthesisInorganic Chemistrychemistry.chemical_compoundImmunoassay methodImmunoassaymedicineMass spectrumOrganic chemistryBioassayMetalloceneApplied Organometallic Chemistry
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N-(2,3,5,6-Tetrafluoropyridyl)sulfoximines: synthesis, X-ray crystallography, and halogen bonding

2020

In the presence of KOH, NH-sulfoximines react with pentafluoropyridine to give N-(tetrafluoropyridyl)sulfoximines (NTFP-sulfoximines) in moderate to excellent yields. Either a solution-based or a superior solvent-free mechanochemical protocol can be followed. X-Ray diffraction analyses of 26 products provided insight into the bond parameters and conformational rigidity of the molecular scaffold. In solid-state structures, sulfoximines with halo substituents on the S-bound arene are intermolecularly linked by C–X⋯OS (X = Cl, Br) halogen bonds. Hirshfeld surface analysis is used to assess the type of non-covalent contacts present in molecules. For mixtures of three different S-pyridyl-substit…

1h nmr spectroscopyHalogen bond010405 organic chemistryChemistryOrganic Chemistrychemistry.chemical_element010402 general chemistry01 natural sciencesNitrogenOxygen0104 chemical sciencesCrystallographyHalogenX-ray crystallographyMoleculeOrganic Chemistry Frontiers
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Bis-macrocyclic Ligands with Two Ferrocenyl End Groups, and Their Tetranuclear Dicopper(I) Compounds

1999

A series of bismacrocyclic ligands with two ferrocenyl groups, exo/endo-1,1‘:1‘ ‘,1‘ ‘‘-[1,2,4,5-tetrakis(5-aza-2-thiahexa-5-enyl)benzene]bisferrocene (exo/endo-FeBeFe), 1,1‘:1‘ ‘,1‘ ‘‘-[1,2:1‘,2‘-tetrakis(5-aza-2-thiahexa-5-enyl)ethene]bisferrocene (1,2-FeEnFe), 1,1‘:1‘ ‘,1‘ ‘‘-[1,1‘:2,2‘-tetrakis(5-aza-2-thiahexa-5-enyl)ethene]bisferrocene (1,1-FeEnFe), 1,1‘:1‘ ‘,1‘ ‘‘-[tetrakis(5-aza-2-thiahexa-5-enyl)methane]bisferrocene (FeMeFe), and their dicopper(I) compounds have been synthesized and characterized (electrochemistry, IR, NMR and Mossbauer spectroscopy). The molecular structure of endo-FeBeFe has been determined by X-ray structure analysis and the copper(I)-induced discrimination of t…

1h nmr spectroscopyStructure analysisStereochemistryChemistrychemistry.chemical_elementElectrochemistryMedicinal chemistryCopperInorganic Chemistrychemistry.chemical_compoundMössbauer spectroscopyMoleculePhysical and Theoretical ChemistryBenzeneInorganic Chemistry
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First synthesis of single-“strapped cyclam-porphyrins”

1994

The first synthesis of strapped cyclam porphyrins is described ; these will be studied as dioxygen carriers as well as cytochrome C oxidase models. The original derivatives are characterized by mass spectrometry and 1H NMR spectroscopy. The cofacial conformation of the two different macrocycles is confirmed by 1H NMR data.

1h nmr spectroscopybiology010405 organic chemistryStereochemistryOrganic ChemistryNuclear magnetic resonance spectroscopy010402 general chemistryMass spectrometry[ CHIM ] Chemical Sciences01 natural sciencesBiochemistry0104 chemical scienceschemistry.chemical_compoundchemistry[CHIM] Chemical SciencesDrug DiscoveryCyclamProton NMRbiology.proteinLactam[CHIM]Chemical SciencesCytochrome c oxidaseComputingMilieux_MISCELLANEOUSCyclophaneTetrahedron Letters
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Physico-chemical investigation of the state of cyanamide confined in AOT and lecithin reversed micelles

2004

Sodium bis(2-ethylhexyl)sulfosuccinate (AOT) and lecithin reversed micelles containing cyanamide have been investigated by small-angle X-ray scattering, FT-IR, and 1H NMR spectroscopy at various cyanamide-to-surfactant molar ratio (X) and at fixed surfactant concentration (0.1 mol kg-1). Experimental data are consistent with a model of cyanamide molecules confined in reversed micelles, quite uniformly distributed among them and mainly located among surfactant headgroups. SAXS data analysis leads also to hypothesize a unidimensional growth of the reversed micelles with increasing the X value. Moreover, the cyanamide state and the cyanamide/cyanamide interactions in reversed micelles have bee…

1h nmr spectroscopyfood.ingredientSodiumASSEMBLIESchemistry.chemical_elementMicelleLecithinSurfaces Coatings and FilmsFT-IRchemistry.chemical_compoundfoodAEROSOL-OTchemistrySOLVATION DYNAMICSMICROEMULSIONSMaterials ChemistryNANOPARTICLESOrganic chemistryCyanamidePhysical and Theoretical ChemistryACETAMIDENuclear chemistrySettore CHIM/02 - Chimica Fisica
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CCDC 145655: Experimental Crystal Structure Determination

2000

Related Article: J.T.Kovalainen, E.Wegelius, J.A.M.Christiaans, J.Huuskonen, J.Gynther|2000|Acta Crystallogr.,Sect.C:Cryst.Struct.Commun.|56|e216|doi:10.1107/S0108270100005291

2(S)-Amino-3-(1H-imidazol-4(5)-yl)propyl 4-bromobenzyl ether dihydrochlorideSpace GroupCrystallographyCrystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates
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CCDC 1421617: Experimental Crystal Structure Determination

2016

Related Article: Jakob Wudarczyk, George Papamokos, Vasilis Margaritis, Dieter Schollmeyer, Felix Hinkel, Martin Baumgarten, George Floudas, Klaus Müllen|2016|Angew.Chem.,Int.Ed.|55|3220|doi:10.1002/anie.201508249

22-Dimethyl-23-dihydro-1H-benzimidazole-4567-tetracarbonitrile tetrahydrofuran solvateSpace GroupCrystallographyCrystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates
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CCDC 1035162: Experimental Crystal Structure Determination

2014

Related Article: Felicitas Lips, Akseli Mansikkamäki, James C. Fettinger, Heikki M. Tuononen, Philip P. Power|2014|Organometallics|33|6253|doi:10.1021/om500947x

23-Diphenyl-11-bis((22''66''-tetraisopropyl-11':3'1''-terphenyl-2'-yl)sulfanyl)-1H-silireneSpace GroupCrystallographyCrystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates
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CCDC 734965: Experimental Crystal Structure Determination

2010

Related Article: B.R.Aluri, S.Burck, D.Gudat, M.Niemeyer, O.Holloczki, L.Nyulaszi, P.G.Jones, J.Heinicke|2009|Chem.-Eur.J.|15|12263|doi:10.1002/chem.200901753

25-Dimethyl-1H-13-benzazaphospholeSpace GroupCrystallographyCrystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates
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CCDC 1414524: Experimental Crystal Structure Determination

2016

Related Article: Vanessa Soto-Cerrato, Pilar Manuel-Manresa, Elsa Hernando, Silvia Calabuig-Fariñas, Alicia Martínez-Romero, Víctor Fernández-Dueñas, Kristoffer Sahlholm, Thomas Knöpfel, María García-Valverde, Ananda M. Rodilla, Eloisa Jantus-Lewintre, Rosa Farràs, Francisco Ciruela, Ricardo Pérez-Tomás, and Roberto Quesada|2015|J.Am.Chem.Soc.|137|15892|doi:10.1021/jacs.5b09970

2-((hexylamino)methylene)-5-(1H-indol-2-yl)-3-methoxy-2H-pyrrolium chlorideSpace GroupCrystallographyCrystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates
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