Search results for "2019"
showing 10 items of 1190 documents
Explorando las desigualdades sociales y formas de contrarrestarlas
2019
Production of INCASI Project H2020-MSCA-RISE-2015 GA 691004 La propuesta de este artículo es presentar una experiencia actual de innovación docente en la que se vincula la enseñanza de la Sociología con la investigación desarrollada en el proyecto europeo INCASI: International Network for Comparative Analysis of Social Inequalities. La experiencia docente se aplica en la asignatura de Sociología, con alumnado de primer curso, del grado de Gestión y Administración Pública, de la Facultad de Derecho, de la Universidad de Barcelona. El eje central del trabajo desarrollado por el alumnado es realizar una investigación sociológica exploratoria sobre una desigualdad social y observar e idear polí…
The cell nucleus. A study in Burgundy
2019
ABSTRACT Wilhelm Bernhard’s revolutionary microscopy techniques helped him put forward the hypothesis of specialized compartmentalization of the nucleus. He also described for the first time the nuclear bodies and peri-chromatin fibrils, and demonstrated that these granules contain an RNA component. The tradition of biennial workshops, named after this great scientist, continues, and this year it took place in the heart of Burgundy, in Dijon, France (May 20–24, 2019, organized by INSERM UMR1231, UBFC), where well-fed participants emphasized the importance of viewing the cell nucleus as a hub of specialized colloidal compartments that orchestrate replication, transcription and nuclear transp…
Immune Response Failure in Paucisymptomatic Long-Standing SARS-CoV-2 Spreaders
2021
The coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has rapidly spread throughout the world. This disease has a spectrum of different clinical pictures with different outcomes. Herein, we report all the data from three paucisymptomatic patients during a hospital stay that might represent a paradigmatic example of the method by which SARS-CoV-2 is shed. We demonstrated the lack of an adequate qualitative and quantitative immune response by multiparametric flow cytometry analysis. Our data can provide a new perspective about the method by which SARS-CoV-2 is shed and the clinical weight of viral persistence. In all three cases, the …
Diabetic Kidney Disease and COVID-19: The Crash of Two Pandemics
2020
Rationale and evidence on the use of tocilizumab in COVID-19: A systematic review. Authors’ reply
2021
Adoption of digital innovations in rural enterprises during COVID-19
2021
The COVID-19 pandemic has rapidly affected the operating conditions of enterprises. Traditional customers and operational models are changing radically in the short term. Digitalisation and digital methods provide an opportunity to re-organise working methods and create a new kind of business to replace old methods and business models. Compared to urban enterprises, rural enterprises have less experience with digital tools and are less likely to adopt digital innovations. This makes rural enterprises especially vulnerable. The purpose of this study is to provide insights into how micro-enterprises and small and medium-sized enterprises in rural areas have addressed the COVID-19 pandemic, th…
Stay at Home and Teach: A Comparative Study of Psychosocial Risks Between Spain and Mexico During the Pandemic
2020
Context The emergency situation caused by coronavirus disease 2019 (COVID-19) has affected different facets of society. Although much of the attention is focused on the health sector, other sectors such as education have also experienced profound transformations and impacts. This sector is usually highly affected by psychosocial risks, and this could be aggravated during the current health emergency. Psychosocial risks may cause health problems, lack of motivation, and a decrease of effectiveness at work, which in turn affect the quality of teaching. Despite their importance, there are hardly any studies that analyze psychosocial risks of non-university teachers during a health emergency su…
Orthostatic hypotension and health outcomes: an umbrella review of observational studies
2019
To investigate potential relationships between orthostatic hypotension (OH) and negative health outcomes and mortality, through an umbrella review with integrated meta-analyses. Orthostatic hypotension is significantly associated with several negative outcomes in older people, but a suggestive evidence is available only for higher risk of coronary heart disease congestive heart failure, stroke, falls dementia, and all-cause mortality. Orthostatic hypotension seems to be significantly associated with several negative health outcomes in older people, even if only associations with coronary heart disease, congestive heart failure, stroke, falls, dementia, and all-cause mortality are supported …
Severe asthma at COVID-19 time: what is new on biologic therapies.
2021
COVID-19 Vaccination Willingness and Hesitancy in Patients With Inflammatory Bowel Diseases: Analysis of Determinants in a National Survey of the Ita…
2021
The coronavirus disease 2019 (COVID-19) pandemic has not finished yet, and the most promising option towards its ending is widespread vaccination. Because patients with inflammatory bowel diseases (IBDs), namely Crohn’s disease (CD) and ulcerative colitis (UC), often require immune-modifying treatment, which might increase the risk of opportunistic infection,1 their vaccination history for several infectious diseases is routinely checked, and when inadequate, vaccination is performed at diagnosis or ideally before immune suppressive treatment is started.1 However, IBD patients were not found to be at an increased risk of developing COVID-19 or of experiencing a more severe disease course.2