Search results for "26"
showing 10 items of 3194 documents
Memory for time intervals is impaired in left hemi-Parkinson patients.
2004
The basal ganglia have been proposed as one of the neural correlates of timekeeping functions. Both encoding and memory retrieval components for time perception are impaired in Parkinson's disease (PD). The aim of our study was to investigate in hemi-Parkinsonian patients the existence of a specific alteration in memory for time depending on the affected side, to better understand the contribution of the left or right basal ganglia circuits in different components of time perception. Right and left hemi-PD patients performed a time reproduction task in which they were required to reproduce in the same session short (5 s) and long (15 s) time intervals, in off- and on-therapy condition. Whil…
Neutralization of acid and base solutions by Reverse Electrodialysis with Bipolar Membranes: a sustainable way to recover energy
2020
The large amount of acidic wastewaters produced in various industrial processes can have a large economic and environmental impact. Companies producing waste acid solutions have to send them to specific sites for the neutralization with alkaline solutions. However, efforts have been devoted so far to promote the acid recovery or its reuse. In the perspective of a more circular manufacturing approach, the present work proposes for the first time the use of the novel Bipolar Membrane Reverse Electrodialysis technology as a viable on-site way to convert the chemical energy associated to the pH gradient of waste acid/base solutions into electrical energy. Bipolar Membrane Reverse Electrodialysi…
L’ampliamento come occasione di recupero della memoria e dell’identità
2012
We present the enlargement plan of an isolated cemetery in a small town of the west Sicily as it exemplifies some way to carry out the design for an “addition”. The enlargement faces a still readable and characteristic nineteenth-century building. Even introducing unavoidable innovative characteristics, the architecture we designed tries to resolve the difficult relationship between the new portion and the old cemetery, bell shaped, in steep slope above the town. The recovery of this place for collective memory, once realized as a closed enclosure, is realized by the mediation of a space which seeks to maintain, recover and reinforce the identity of places altered in the last years by uncon…
In vitro glucuronidation of 7-hydroxycoumarin derivatives in intestine and liver microsomes of Beagle dogs
2019
Beagle dog is a standard animal model for evaluating nonclinical pharmacokinetics of new drug candidates. Glucuronidation in intestine and liver is an important first-pass drug metabolic pathway, especially for phenolic compounds. This study evaluated the glucuronidation characteristics of several 7-hydroxycoumarin derivatives in beagle dog's intestine and liver in vitro. To this end, glucuronidation rates of 7-hydroxycoumarin (compound 1), 7-hydroxy-4-trifluoromethylcoumarin (2), 6-methoxy-7-hydroxycoumarin (3), 7-hydroxy-3-(4-tolyl)coumarin (4), 3-(4-fluorophenyl)coumarin (5), 7-hydroxy-3-(4-hydroxyphenyl)coumarin (6), 7-hydroxy-3-(4-methoxyphenyl)coumarin (7), and 7-hydroxy-3-(1H-1,2,4-t…
LACOSAMIDE: TERAPIA IN ADD ON NEL TRATTAMENTO DELL’EPILESSIA PARZIALE
2012
Razionale ed obiettivi: La lacosamide è una nuova molecola con spiccata attività anticonvulsivante utilizzata nelle forme di epilessia ad esordio focale. Obiettivo del nostro studio è quello di valutare la tollerabilità, le interazioni farmacologiche e l’efficacia di questo nuovo farmaco usato in associazione ai vecchi ed ai nuovi farmaci antiepilettici. Pazienti e metodi: Abbiamo arruolato 30 pazienti afferenti al nostro Centro per la Diagnosi e la Cura dell’Epilessia dell’Università degli studi di Palermo affetti da epilessia parziale in bi-politerapia. L’età media dei pazienti era di 36,6 anni, l’età media di esordio della prima crisi di 15,9; 25 erano farmacoresistenti e 22 hanno presen…
Sagittal Plane Hip, Knee, and Ankle Biomechanics and the Risk of Anterior Cruciate Ligament Injury: A Prospective Study
2018
Background: Stiff landings with less knee flexion and high vertical ground-reaction forces have been shown to be associated with an increased risk of anterior cruciate ligament (ACL) injury. The literature on the association between other sagittal plane measures and the risk of ACL injuries with a prospective study design is lacking. Purpose: To investigate the relationship between selected sagittal plane hip, knee, and ankle biomechanics and the risk of ACL injury in young female team-sport athletes. Study Design: Case-control study; Level of evidence, 3. Methods: A total of 171 female basketball and floorball athletes (age range, 12-21 years) participated in a vertical drop jump test usin…
Resultados vs. Realidad: un ejemplo en las actitudes lingüísticas
2018
Source at https://doi.org/10.7203/Normas.v8i1.13437. Este artículo presenta una revisión de parte de un estudio de investigación sobre actitudes lingüísticas: “Estudio sobre las actitudes lingüísticas en Andalucía: andaluz oriental y andaluz occidental” (Ruiz Pareja, 2015). El objetivo de este trabajo es arrojar un poco de luz sobre el contraste que existe en Sociolingüística entre las actitudes afectivas y cognitivas, que además están presentes en numerosos cuestionarios y estudios en esta disciplina. Para ello se repite parte del cuestionario original, donde parecía haber cierta contradicción entre actitudes y comportamientos. Los nuevos resultados indican que esta contradicción sigue exi…
Effect of extracellular vesicles from CSF of multiple sclerosis patients and healthy controls on astrocytes in culture
2017
INTRODUCTION Secretion of extracellular vesicles (EVs) and EV-mediated exchange of molecules among brain cells, under physiological conditions, has been described years ago. At the same time, ability of EVs to transfer proteins and nucleic acids to the surrounding cells, thus modifying their phenotypes, has been clearly demonstrated for tumor cells of different origins, including brain cancers. More recently, involvement of EVs in pathological processes affecting the Central Nervous System (CNS), and their capacity of transferring damaging cargoes have been also suggested. To explore these functions, we exposed primary cultures of astrocytes to EVs isolated from cerebral spinal fluid (CSF) …
En kvalitativ studie om ungdom, tro og psykisk helse : Troen har ganske mye å si for din psykiske helse. Det er et fundament for hvordan du takler li…
2019
Masteroppgave psykisk helsearbeid ME504 - Universitetet i Agder 2019 Background:The theme of this study is "Youth, Faith and Mental Health". The background for choosing this theme is the major focus of our time on adolescents and their mental health. According to the Institute of Public Health (2009), 15-20% of children and youth have mental health problems, with complex symptoms that influences their well-being, learning ability, daily activities and socializing with others.Purpose:The purpose of this study is to investigate the coherence between Christian faith and mental health in adolescents. The following issue was selected: what coherences does youth experience concerning their person…
Marx y Engels y la división sexual del trabajo en la familia: ambigüedades, equívocos y vacíos teóricos
2018
Dada la importante influencia de Marx y Engels en el análisis de la estructura social, no sorprende el notable impacto de su obra en el estudio del papel de la mujer en la familia. Sin embargo, su herencia en este ámbito sociológico ha dado lugar a interpretaciones muy polarizadas. Este artículo quiere aportar algo de luz evidenciando las contradicciones del marxismo al estudiar el papel de la mujer en la familia. Para ello se comparan las contribuciones de Marx y Engels para calibrar posibles diferencias en las posturas de dos autores que en otros ámbitos han presentado un pensamiento muy homogéneo. Los resultados obtenidos permiten afirmar que, a pesar de su innegable influencia en el pen…