Search results for "28"
showing 10 items of 3583 documents
Descriptive study on subjective experience of genetic testing with respect to relationship, family planning and psychosocial wellbeing among women wi…
2021
AbstractBackgroundDue to increased risk of endometrial and ovarian cancer, women belonging to known Lynch Syndrome (LS) families are recommended to undergo germline testing. Current practice in Finland is to offer counselling to women with pathogenic variant and advocate risk-reducing surgery (RRS) after completion of childbirth. The present study aimed to clarify the impacts of positive germline testing on family planning and reproductive decisions of these women, which are relatively unknown.MethodsSeventy-nine carriers of germline MMR gene pathogenic variant (path_MMR)were identified from the Finnish LS Registry as having genetic testing performed before the age of 45 years and not havin…
Pienryhmäohjaajien vertaisryhmä andragogisessa koulutuksessa
2014
Erilaisten yhteistyön muotojen, vuorovaikutuksen ja jakamisen merkitystä korostetaan tutkimuksissa, mutta opettajien ja ohjaajien kollegiaalisen tuen muotoja ei juurikaan edistetä rakenteellisin tai organisatorisin keinoin. Vertaistuki vahvistaa ohjaajien työssä kehittymistä ja jaksamista sekä koulutuksen kehittämistä.
Desempleo y crisis Económica. Los casos de España e Italia
2018
En este artículo se analiza la diferente reacción que los mercados laborales italiano y español han tenido ante la crisis económica: la tasa de paro italiana entre 2006 y 2012, ha crecido relativamente poco (pasando del 7,6 al 10,9%) mientras que la es-pañola se ha casi triplicado, pasando del 9 al 24,4%. Para ello se han analizado datos relativos a: el mercado del trabajo, la situación socioeconómica y la legislación exis-tente. Tras el estudio realizado, tres parecen ser las discrepancias más relevantes: 1) las diferencias en las tasas de actividad femenina entre ambos países; 2) la menor apertura del mercado laboral italiano en los últimos 20 años; y, 3) la diferente legis-lación sobre d…
Uniformization of two-dimensional metric surfaces
2014
We establish uniformization results for metric spaces that are homeomorphic to the Euclidean plane or sphere and have locally finite Hausdorff 2-measure. Applying the geometric definition of quasiconformality, we give a necessary and sufficient condition for such spaces to be QC equivalent to the Euclidean plane, disk, or sphere. Moreover, we show that if such a QC parametrization exists, then the dilatation can be bounded by 2. As an application, we show that the Euclidean upper bound for measures of balls is a sufficient condition for the existence of a 2-QC parametrization. This result gives a new approach to the Bonk-Kleiner theorem on parametrizations of Ahlfors 2-regular spheres by qu…
Descripción y comparación del perfil de expresión del sistema LIN28/Let-7 y microRNAs asociados en tejido placentario sano y tejido placentario proce…
2017
INTRODUCCIÓN El embarazo ectópico (EE) es una complicación precoz de la gestación en la cual un óvulo fecundado se implanta en un sitio distinto al endometrio de la cavidad uterina. siendo el lugar más frecuente la trompa de Falopio (95-98%). Su incidencia resulta variable en la literatura médica, oscilando entre el 0,6 y el 2% de los embarazos documentados, presentándose con picos más altos en la adolescencia. Este continúa siendo la principal causa de muerte materna en las primeras etapas de la gestación (4-10% de las muertes relacionadas con el embarazo en países desarrollados) y una de las urgencias quirúrgicas más frecuentes del primer trimestre. El EE no es solo una causa importante d…
Esteban, Fernando Osvaldo (ed.) (2013). Espacios transnacionales de la migración latinoamericana en Europa
2014
Ressenya de l'obra editada per Fernando Osvaldo Esteban apareguda el 2013, Espacios transnacionales de la migración latinoamericana en Europa. Buenos Aires: Antropofagia. 171 p. ISBN 978-987-1238-96-5
A Bayesian Mixed-Methods Analysis of Basic Psychological Needs Satisfaction through Outdoor Learning and Its Influence on Motivational Behavior in Sc…
2017
Research has shown that outdoor educational interventions can lead to students' increased self-regulated motivational behavior. In this study, we searched into the satisfaction of basic psychological needs (BPN), i.e., autonomy support, the learners' experience of competence, and relatedness, both within the peer group and with their teachers, through outdoor learning. From 2014 to 2016, n = 281 students attended “research weeks” at a Student Science Lab in the Alpine National Park Berchtesgaden (Germany). The program is a curriculum-based one-week residential course, centered on a 2-day research expedition. Both before and after the course, students completed a composite questionnaire addr…
Simon Starling, A l’ombre du pin tordu
2018
L’exposition consacrée à l’artiste britannique Simon Starling (1967/) à Sérignan témoigne exemplairement du tournant pris depuis les œuvres des années 1990 et 2000 dont l’une, Shedboatshed, lui a valu le prix Turner en 2005. À vrai dire, l’inflexion de son art vers une interrogation portant non sur l’identité, mais sur la présence était sensible dans une précédente exposition dédoublée entre le Mac/Val et le Parc Saint Léger en 2009. Pratiques de la déconstruction et de la reconstruction, le...
Practical Considerations for the Daratumumab Management in Portuguese Routine Clinical Practice: Recommendations From an Expert Panel of Hematologists
2022
The recent therapeutic progress in multiple myeloma (MM) has led to the introduction of novel and highly potent drug classes. Daratumumab was the first CD38-targeting antibody showing to be effective and safe in MM patients as monotherapy and in combination regimens, which led to its rapid implementation in clinical practice. Considering that treatment discontinuation for drug-related adverse events can impact patients’ quality of life and outcomes, the treatment decision should consider different factors and be weighted for each patient individually. Here, we aimed to guide clinicians using daratumumab treatment for MM by addressing practical real-world considerations based on an expert pa…
High Output Heart Failure in Multiple Myeloma: Pathogenetic Considerations.
2022
The high output heart failure is a clinical condition in which the systemic congestion is associated to a high output state, and it can be observed in a non-negligible percentage of hematological diseases, particularly in multiple myeloma, a condition in which the risk of adverse cardiovascular events may increase, with a worse prognosis for patients. For this reason, though an accurate literature search, we provided in this review a complete overview of different pathogenetic mechanisms responsible for high output heart failure in multiple myeloma. Indeed, this clinical finding is present in the 8% of multiple myeloma patients, and it may be caused by artero-venous shunts, enhanced angioge…