Search results for "2D"

showing 10 items of 305 documents

About the link between the detailed description of transitions in an ion and the average-ion models

2009

We study the link which exists between microscopic (detailed) models for the evolution of the electronic configurations in a population of ions and the macroscopic (average ion) models. Rigorous asymptotics are presented in situations where they exist (large temperature; almost empty or almost full shells), and numerical simulations are presented.

Physicseducation.field_of_studyApplied MathematicsGeneral MathematicsAverage-ion modelsrigorous asymptoticsPopulationcomparison of solutions34C11Ion37M0535Q40Statistical physicsElectron configurationmicroscopic models82D10Link (knot theory)education
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3D cultures of rat astrocytes and brain capillary endothelial cells on Poly-L-lactic acid scaffolds

2016

Tissue engineering is an emerging multidisciplinary field that aims at reproducing in vitro and/or in vivo tissues with morphological and functional features similar to the biological tissue of the human body. In this communication we report setting of three-dimensional structures able to mimic the extracellular matrix of the nervous system: we prepared Poly-L-Lactic Acid (PLLA) porous scaffolds via thermally induced phase separation (TIPS), and investigated the parameters that influence porosity, average pore size and degree of interconnection, i.e. polymer concentration, temperature and time of process. Astrocytes and brain capillary endothelial cells (BCECs) were cultured on these three-…

Poly-L-Lactic Acid (PLLA) porous scaffolds Astrocytes brain capillary endothelial cells (BCECs) 2D culture systems and 3D culture systemsSettore ING-IND/22 - Scienza E Tecnologia Dei MaterialiSettore BIO/13 - Biologia ApplicataSettore BIO/10 - BiochimicaSettore BIO/06 - Anatomia Comparata E Citologia
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Stability and l1-gain analysis for positive 2D T–S fuzzy state-delayed systems in the second FM model

2014

This paper considers the problems of delay-dependent stability and l"1-gain analysis for a class of positive two-dimensional (2D) Takagi-Sugeno (T-S) fuzzy linear systems with state delays described by the second FM model. Firstly, the co-positive type Lyapunov function method is applied to establish sufficient conditions of asymptotical stability for the addressed positive 2D T-S fuzzy system. Then, the l"1-gain performance analysis for the positive 2D T-S fuzzy delayed system is studied. All the obtained results are formulated in the form of linear matrix inequalities (LMIs) which are computationally tractable. Finally, an illustrative example is given to verify the effectiveness of the p…

Positive 2D systemsLyapunov functionT-S fuzzy systemsCognitive NeuroscienceLinear systemLinear matrix inequalityDelay-dependent stabilityComputer Science Applications1707 Computer Vision and Pattern RecognitionFuzzy control systemState (functional analysis)Fuzzy logicStability (probability)Computer Science Applicationssymbols.namesakeArtificial IntelligenceControl theorysymbolsCo-positive type Lyapunov functionFuzzy numberCo-positive type Lyapunov function; Delay-dependent stability; Positive 2D systems; T-S fuzzy systems; Computer Science Applications1707 Computer Vision and Pattern Recognition; Cognitive Neuroscience; Artificial IntelligenceMathematicsNeurocomputing
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Dual film-like organelles enable spatial separation of orthogonal eukaryotic translation

2021

Summary Engineering new functionality into living eukaryotic systems by enzyme evolution or de novo protein design is a formidable challenge. Cells do not rely exclusively on DNA-based evolution to generate new functionality but often utilize membrane encapsulation or formation of membraneless organelles to separate distinct molecular processes that execute complex operations. Applying this principle and the concept of two-dimensional phase separation, we develop film-like synthetic organelles that support protein translation on the surfaces of various cellular membranes. These sub-resolution synthetic films provide a path to make functionally distinct enzymes within the same cell. We use t…

Protein designComputational biologyBiology2D phase separationArticleGeneral Biochemistry Genetics and Molecular BiologySynthetic biologyEukaryotic translationOrganelleHumansRNA MessengerAmino AcidsOrganellesmembrane signalingsynthetic biomolecular condensatesProteinsTranslation (biology)Intracellular MembranesProtein engineeringGenetic codeenzyme engineeringHEK293 Cellsgenetic code expansionEukaryotic CellsGenetic CodeProtein Biosynthesisorthogonal translationsynthetic biologyRibosomesFunction (biology)Cell
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Proteomic analysis of exosome-like vesicles derived from breast cancer cells.

2012

Background/Aim: The phenomenon of membrane vesicle-release by neoplastic cells is a growing field of interest in cancer research, due to their potential role in carrying a large array of tumor antigens when secreted into the extracellular medium. In particular, experimental evidence show that at least some of the tumor markers detected in the blood circulation of mammary carcinoma patients are carried by membrane-bound vesicles. Thus, biomarker research in breast cancer can gain great benefits from vesicle characterization. Materials and Methods: Conditioned medium was collected from serum starved MDA-MB-231 sub-confluent cell cultures and exosome-like vesicles (ELVs) were isolated by ultra…

ProteomicsBreast NeoplasmsExosomesCulture Media Serum-FreeNeoplasm ProteinsBreast cancer extracellular vesicles protein biomarker 2D-PAGE proteomic profiling MALDI-ToF mass spectrometry MDA-MB-231 cellsMicroscopy Electron TransmissionSettore BIO/13 - Biologia ApplicataTandem Mass SpectrometrySettore BIO/10 - BiochimicaCell Line TumorHumansFemaleSettore BIO/06 - Anatomia Comparata E CitologiaChromatography LiquidAnticancer research
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Effect of ivermectin on the liver of gilthead sea bream Sparus aurata: a proteomic approach.

2010

23 p., 2 tablas, 4 figuras y bibliografía

ProteomicsFish ProteinsEnvironmental EngineeringNew biomarkersSparidaeProteomeHealth Toxicology and MutagenesisDifference gel electrophoresisBiologyIvermectinAquaculturemedicineEnvironmental ChemistryAnimalsGilthead seabreamIvermectinAntiparasitic AgentsEcologybusiness.industryPublic Health Environmental and Occupational HealthHepatotoxinLipid metabolismAquatic animalGeneral MedicineGeneral ChemistryMetabolismbiology.organism_classificationPollutionSea BreamMass spectrometry (MS)BiochemistryLiver2D-DIGEbusinessBiomarkersWater Pollutants Chemicalmedicine.drugChemosphere
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Differential proteomic analysis of an engineered Streptomyces coelicolor strain reveals metabolic pathways supporting growth on n-hexadecane

2012

The alkB gene, encoding an alkane monooxygenase in the actinomycete Gordonia sp. SoCg, was expressed in the non-alkane-degrading actinomycete Streptomyces coelicolor M145. The resulting engineered strain, M145-AH, can grow on n-hexadecane as sole carbon source. To unravel proteins associated with growth on n-alkanes, proteome of M145-AH after 6, 24, and 48 h of incubation in the Bushnell-Haas (BH) mineral medium containing n-hexadecane as sole carbon source (H condition) and in BH without any carbon source (0 condition) were compared using 2D-differential gel electrophoresis. Proteome analysis revealed significant changes only at 48 h, showing 48 differentially abundant proteins identified …

ProteomicsProteomeAlkBProtein metabolismGene ExpressionStreptomyces coelicolorSettore BIO/19 - Microbiologia GeneraleProteomicsApplied Microbiology and BiotechnologyStreptomyceschemistry.chemical_compoundAlkanesElectrophoresis Gel Two-DimensionalbiologyStreptomyces coelicolorProteomicGeneral MedicineMetabolism2d-dige analysisMembrane transportbiology.organism_classificationCarbonRecombinant ProteinsStreptomycesCulture MediaN-alkane monoxygenaseStreptomyceN-hexadecane utilizationchemistryBiochemistryEngineered strainProteomebiology.protein2D-DIGE analysiCytochrome P-450 CYP4AMetabolic Networks and PathwaysBiotechnologyApplied Microbiology and Biotechnology
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Adaptative biochemical pathways and regulatory networks in Klebsiella oxytoca BAS-10 producing a biotechnologically relevant exopolysaccharide during…

2012

Abstract Background A bacterial strain previously isolated from pyrite mine drainage and named BAS-10 was tentatively identified as Klebsiella oxytoca. Unlikely other enterobacteria, BAS-10 is able to grow on Fe(III)-citrate as sole carbon and energy source, yielding acetic acid and CO2 coupled with Fe(III) reduction to Fe(II) and showing unusual physiological characteristics. In fact, under this growth condition, BAS-10 produces an exopolysaccharide (EPS) having a high rhamnose content and metal-binding properties, whose biotechnological applications were proven as very relevant. Results Further phylogenetic analysis, based on 16S rDNA sequence, definitively confirmed that BAS-10 belongs t…

Proteomicsmetal binding exopolysaccharideRhamnoseeducationlcsh:QR1-502BioengineeringSettore BIO/19 - Microbiologia GeneraleFerric CompoundsApplied Microbiology and BiotechnologyCitric Acidlcsh:Microbiology03 medical and health scienceschemistry.chemical_compoundAcetic acidRNA Ribosomal 16SGene Regulatory NetworksPhylogeny030304 developmental biology2. Zero hunger0303 health sciencesbiology030306 microbiologyResearchKlebsiella oxytocaKlebsiella oxytocabiology.organism_classificationBacterial strainKlebsiella oxytoca; 2D-DIGE analysis; metal binding exopolysaccharide;Metabolic pathwaychemistryBiochemistryFermentation2D-DIGE analysiFermentationEnergy sourceCitric acidMetabolic Networks and PathwaysBiotechnology
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On the quasi-isometric and bi-Lipschitz classification of 3D Riemannian Lie groups.

2021

AbstractThis note is concerned with the geometric classification of connected Lie groups of dimension three or less, endowed with left-invariant Riemannian metrics. On the one hand, assembling results from the literature, we give a review of the complete classification of such groups up to quasi-isometries and we compare the quasi-isometric classification with the bi-Lipschitz classification. On the other hand, we study the problem whether two quasi-isometrically equivalent Lie groups may be made isometric if equipped with suitable left-invariant Riemannian metrics. We show that this is the case for three-dimensional simply connected groups, but it is not true in general for multiply connec…

Pure mathematicsDimension (graph theory)Quasi-isometricisometric53C2301 natural sciencesdifferentiaaligeometria0103 physical sciencesSimply connected spaceMathematics::Metric Geometry0101 mathematicsIsometric20F65bi-LipschitzMathematicsTransitive relationOriginal PaperLie groupsRiemannian manifold010102 general mathematics22D05ryhmäteoriaLie groupBi-Lipschitz; Classification; Isometric; Lie groups; Quasi-isometric; Riemannian manifoldRiemannian manifoldLipschitz continuityClassificationmetriset avaruudetquasi-isometricBi-LipschitzclassificationDifferential geometrygeometria010307 mathematical physicsGeometry and TopologyMathematics::Differential GeometryCounterexampleGeometriae dedicata
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Interaction between flavour compounds and beta-lactoglobulin: approach by NMR and 2D/3D-QSAR studies of ligands

2004

 author cannot archive publisher's version/PDF; International audience; Interactions between flavour compounds and beta-lactoglobulin (BLG) have been the subject of several studies, but there are no unanimous binding site explanations. In our laboratory, interactions between BLG, and two flavour compounds, beta-ionone and gamma-decalactone, were studied by 2D-NMR spectroscopy. It appears that several amino acids affected by binding of gamma-decalactone are buried in the central cavity, whereas binding of beta-ionone affects amino acids located in a groove near the outer surface of the protein. 2D/3D-QSAR studies were performed using QSAR+ module of Cerius2 and Catalyst. The QSAR equation pr…

Quantitative structure–activity relationshipAROMAMolecular modelStereochemistry01 natural sciences03 medical and health sciencesComputational chemistryMolecular descriptor[SDV.IDA]Life Sciences [q-bio]/Food engineeringFLAVOURBinding site030304 developmental biology3D-QSAR0303 health sciencesChemistryHydrogen bondLigand[ SDV.IDA ] Life Sciences [q-bio]/Food engineeringGeneral Chemistry[SDV.IDA] Life Sciences [q-bio]/Food engineeringAffinitiesBETA-LACTOGLOBULIN0104 chemical sciences010404 medicinal & biomolecular chemistry2D-QSAR2D-NMRTwo-dimensional nuclear magnetic resonance spectroscopyFood Science
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