Search results for "312"

sj-docx-1-aut-10.1177_13623613211039950 – Supplemental material for Systematic review of prenatal exposure to endocrine disrupting chemicals and auti…

2021

Supplemental material, sj-docx-1-aut-10.1177_13623613211039950 for Systematic review of prenatal exposure to endocrine disrupting chemicals and autism spectrum disorder in offspring by Salvador Marí-Bauset, Isabel Peraita-Costa, Carolina Donat-Vargas, Agustín Llopis-González, Amelia Marí-Sanchis, Juan Llopis-Morales and María Morales Suárez-Varela in Autism

AUT898331_Supplemental_material_Appendix_II – Supplemental material for A framework of evidence-based practice for digital support, co-developed with…

2020

Supplemental material, AUT898331_Supplemental_material_Appendix_II for A framework of evidence-based practice for digital support, co-developed with and for the autism community by Vanessa Zervogianni, Sue Fletcher-Watson, Gerardo Herrera, Matthew Goodwin, Patricia Pérez-Fuster, Mark Brosnan and Ouriel Grynszpan in Autism

Cronica del muy valeroso rey don Fernando, Visnieto del sancto rey don Fernado que gano a Seuilla ... : Este es el rey don Fernado que dizen que muri…

1554

Sign.: A-H8, I6 Port. orlada i a dos tintes, vermella i negra. - Errors en la fol. - Grav. en la port. - Tipus gót. - Capll. orn. - Text a dos col. - Reclams

Innovative teaching strategies in sciences teaching. Case study: teachers of the Rural Education Foundation of Valencia (1958-1985).

2017

Este trabajo aborda la reintroducción de estrategias didácticas en ciencias experimentales en el mundo rural de la provincia de Valencia que tuvo lugar a partir de los años 60 del siglo pasado. Para ello se han analizado documentos relativos al Patronato de Educación Rural (1958-1985), organismo dependiente de la Diputación de Valencia constituido con el objetivo de mejorar la educación en zonas rurales de la provincia. La metodología utilizada en la investigación se fundamenta en el método analítico descriptivo mediante la búsqueda, revisión y análisis de fuentes históricas e iconográficas depositadas en el Archivo de la Diputación Provincial de Valencia. La investigación pretende poner de…

Vicente Lleó Balbastre y el género sicalíptico

2016

Association of maternal prenatal smoking GFI1-locus and cardio-metabolic phenotypes in 18,212 adults

2018

Background: DNA methylation at the GFI1-locus has been repeatedly associated with exposure to smoking from the foetal period onwards. We explored whether DNA methylation may be a mechanism that links exposure to maternal prenatal smoking with offspring's adult cardio-metabolic health.Methods: We meta-analysed the association between DNA methylation at GFI1-locus with maternal prenatal smoking, adult own smoking, and cardio-metabolic phenotypes in 22 population-based studies from Europe, Australia, and USA (n= 18,212). DNA methylation at the GFI1-locus was measured in whole-blood. Multivariable regression models were fitted to examine its association with exposure to prenatal and own adult s…

Calcium in the prevention of postmenopausal osteoporosis: EMAS clinical guide

2017

Abstract Introduction Postmenopausal osteoporosis is a highly prevalent disease. Prevention through lifestyle measures includes an adequate calcium intake. Despite the guidance provided by scientific societies and governmental bodies worldwide, many issues remain unresolved. Aims To provide evidence regarding the impact of calcium intake on the prevention of postmenopausal osteoporosis and critically appraise current guidelines. Materials and methods Literature review and consensus of expert opinion. Results and conclusion The recommended daily intake of calcium varies between 700 and 1200 mg of elemental calcium, depending on the endorsing source. Although calcium can be derived either fro…

PSD3 downregulation confers protection against fatty liver disease

2022

Fatty liver disease (FLD) is a growing health issue with burdening unmet clinical needs. FLD has a genetic component but, despite the common variants already identified, there is still a missing heritability component. Using a candidate gene approach, we identify a locus (rs71519934) at the Pleckstrin and Sec7 domain-containing 3 (PSD3) gene resulting in a leucine to threonine substitution at position 186 of the protein (L186T) that reduces susceptibility to the entire spectrum of FLD in individuals at risk. PSD3 downregulation by short interfering RNA reduces intracellular lipid content in primary human hepatocytes cultured in two and three dimensions, and in human and rodent hepatoma cell…

RISK OF CARDIOVASCULAR DISEASE MORBIDITY AND MORTALITY IN FRAIL AND PRE-FRAIL OLDER ADULTS:RESULTS FROM A META-ANALYSIS AND EXPLORATORY META-REGRESSI…

2017

Frailty is common and associated with poorer outcomes in the elderly, but its role as potential cardiovascular disease (CVD) risk factor requires clarification. We thus aimed to meta-analytically evaluate the evidence of frailty and pre-frailty as risk factors for CVD. Two reviewers selected all studies comparing data about CVD prevalence or incidence rates between frail/pre-frail vs. robust. The association between frailty status and CVD in cross-sectional studies was explored by calculating and pooling crude and adjusted odds ratios (ORs)+/- 95% confidence intervals (CIs); the data from longitudinal studies were pooled using the adjusted hazard ratios (HRs). Eighteen cohorts with a total …

A comprehensive fracture prevention strategy in older adults : The European union geriatric medicine society (EUGMS) statement

2016

Published also in Aging Clinical and Experimental Research, Vol.28, No.4, WOS: 000379034800030 Prevention of fragility fractures in older people has become a public health priority, although the most appropriate and cost-effective strategy remains unclear. In the present statement, the Interest group on falls and fracture prevention of the European union geriatric medicine society (EUGMS), in collaboration with the International association of gerontology and geriatrics for the European region (IAGG-ER), the European union of medical specialists (EUMS), the Fragility fracture network (FFN), the International osteoporosis foundation (IOF) - European society for clinical and economic aspects …