Search results for "38"
showing 10 items of 1730 documents
A quasiconformal composition problem for the Q-spaces
2017
Given a quasiconformal mapping $f:\mathbb R^n\to\mathbb R^n$ with $n\ge2$, we show that (un-)boundedness of the composition operator ${\bf C}_f$ on the spaces $Q_{\alpha}(\mathbb R^n)$ depends on the index $\alpha$ and the degeneracy set of the Jacobian $J_f$. We establish sharp results in terms of the index $\alpha$ and the local/global self-similar Minkowski dimension of the degeneracy set of $J_f$. This gives a solution to [Problem 8.4, 3] and also reveals a completely new phenomenon, which is totally different from the known results for Sobolev, BMO, Triebel-Lizorkin and Besov spaces. Consequently, Tukia-V\"ais\"al\"a's quasiconformal extension $f:\mathbb R^n\to\mathbb R^n$ of an arbitr…
The impact of study design and diagnostic approach in a large multi-centre ADHD study. Part 1: ADHD symptom patterns
2011
Contains fulltext : 96439.pdf (Publisher’s version ) (Open Access) BACKGROUND: The International Multi-centre ADHD Genetics (IMAGE) project with 11 participating centres from 7 European countries and Israel has collected a large behavioural and genetic database for present and future research. Behavioural data were collected from 1068 probands with the combined type of attention deficit/hyperactivity disorder (ADHD-CT) and 1446 'unselected' siblings. The aim was to analyse the IMAGE sample with respect to demographic features (gender, age, family status, and recruiting centres) and psychopathological characteristics (diagnostic subtype, symptom frequencies, age at symptom detection, and com…
A survey on features of allergic rhinitis in children
2013
Objective: A number of epidemiologic studies evaluated the prevalence of allergic rhinitis (AR), but few data are available on its different clinical presentations. We addressed this survey to assess the features of AR in children and adolescents. Methods: Thirty-five centers in Italy included 2623 pediatric patients with rhinitis, of whom 2319 suffered from AR, while 304 had other kinds of rhinitis. For each patient a standardized questionnaire was filled in, including ARIA classification, the duration of symptoms, the allergen identified as clinically relevant, the co-morbidities, the kind of treatment, the response to treatment, the satisfaction with the treatment, and the feasibility of…
Clostridium difficile toxin A induces expression of the stress-induced early gene product RhoB.
2004
Clostridium difficile toxin A monoglucosylates the Rho family GTPases Rho, Rac, and Cdc42. Glucosylation leads to the functional inactivation of Rho GTPases and causes disruption of the actin cytoskeleton. A cDNA microarray revealed the immediate early gene rhoB as the gene that was predominantly up-regulated in colonic CaCo-2 cells after treatment with toxin A. This toxin A effect was also detectable in epithelial cells such as HT29 and Madin-Darby canine kidney cells, as well as NIH 3T3 fibroblasts. The expression of RhoB was time-dependent and correlated with the morphological changes of cells. The up-regulation of RhoB was approximately 15-fold and was based on the de novo synthesis of …
LA RMN NEL FOLLOW UP DELLA FUNZIONALITA’ GONADICA NELLE ADOLESCENTI CON S. DI TURNER
2012
Age-dependent regulation of antioxidant genes by p38α MAPK in the liver
2018
p38α is a redox sensitive MAPK activated by pro-inflammatory cytokines and environmental, genotoxic and endoplasmic reticulum stresses. The aim of this work was to assess whether p38α controls the antioxidant defense in the liver, and if so, to elucidate the mechanism(s) involved and the age-related changes. For this purpose, we used liver-specific p38α-deficient mice at two different ages: young-mice (4 months-old) and old-mice (24 months-old). The liver of young p38α knock-out mice exhibited a decrease in GSH levels and an increase in GSSG/GSH ratio and malondialdehyde levels. However, old mice deficient in p38α had higher hepatic GSH levels and lower GSSG/GSH ratio than young p38α knock-…
Global (pharmacological and non pharmacological) prevention of RSV infection
2012
Un problema emergente: il rachitismo carenziale nei bambini adottati dall’estero.
2006
Analysis methods of safe Coulomb-excitation experiments with radioactive ion beams using the gosia code
2016
With the recent advances in radioactive ion beam technology, Coulomb excitation at safe energies becomes an important experimental tool in nuclear-structure physics. The usefulness of the technique to extract key information on the electromagnetic properties of nuclei has been demonstrated since the 1960's with stable beam and target combinations. New challenges present themselves when studying exotic nuclei with this technique, including dealing with low statistics or number of data points, absolute and relative normalisation of the measured cross sections and a lack of complimentary experimental data, such as excited-state lifetimes and branching ratios. This paper addresses some of these…
La transmissió lingüística intergeneracional a Castelló de la Plana i la Franja: La rellevància dels usos entre progenitors
2020
Fa 50 anys, a Conflicte lingüístic valencià, Rafael L. Ninyoles situava el trencament de la transmissió familiar del català com a resultat i manifestació externa de conflictes socials i de classes, especialment visibles enmig del procés de modernització econòmica i mobilitat social accelerada del País Valencià dels anys 60 del segle XX. En aquest article partim de dos estudis de cas quantitatius sobre la transmissió intergeneracional de les llengües a Castelló de la Plana i les comarques centrals de la Franja per a actualitzar el seu diagnòstic i matisar la visió d'aquest fenomen com a resultat de decisions dels progenitors imposades verticalment a la descendència. Hi proposem que els usos …