Search results for "4 D"
showing 10 items of 15011 documents
Study engagement and burnout profiles among Finnish higher education students
2017
A person-oriented approach was applied to identify profiles of study engagement and burnout (i.e., exhaustion, cynicism, inadequacy) in higher education in a large and representative sample of 12,394 higher education students at different phases of their studies in universities and polytechnics in Finland. Four profiles were identified: Engaged (44%), engaged-exhausted (30%) inefficacious (19%) and burned-out (7%). The engaged students had the most positive engagement accompanied with the least burnout symptoms compared to other groups. The engaged-exhausted students experienced emotional exhaustion simultaneously with academic engagement. The inefficacious group had heightened experience o…
School burnout and engagement profiles among digital natives in Finland: a person-oriented approach
2016
AbstractApplying a person-oriented approach, this study set out to examine what profiles of school engagement and school burnout (i.e., exhaustion, cynicism, inadequacy) can be identified among elementary school children at age 12, a generation also often referred to as the generation of digital natives. We compared the group memberships in their use of socio-digital technologies and related functioning as we expected to find a gap between some digital natives and current educational practices which do not include socio-digital technology in feelings of cynicism towards school. Latent profile analysis identified five groups: Engaged (50%) students, who formed the majority; Stressed (4%) stu…
Genome degeneration and adaptation in a nascent stage of symbiosis
2014
Symbiotic associations between animals and microbes are ubiquitous in nature, with an estimated 15% of all insect species harboring intracellular bacterial symbionts. Most bacterial symbionts share many genomic features including small genomes, nucleotide composition bias, high coding density, and a paucity of mobile DNA, consistent with long-term host association. In this study, we focus on the early stages of genome degeneration in a recently derived insect-bacterial mutualistic intracellular association. We present the complete genome sequence and annotation of Sitophilus oryzae primary endosymbiont (SOPE). We also present the finished genome sequence and annotation of strain HS, a close…
Associations between perceived parental psychological control and internalizing difficulties in emerging adulthood: the role of identity
2016
Our study investigated the associations among two expressions of perceived parental psychological control (dependency-oriented parental control [DPC] and achievement-oriented parental control [APC]), identity, and internalizing difficulties among college-attending emerging adults. In particular, our aim was to examine the potential role of identity in the pathways linking both DPC and APC to internalizing difficulties. Our participants included 495 Italian college students (49% males), between 19 and 28 years of age (mean = 23.37 years, standard deviation = 2.35). Our findings highlighted the existence of associations between APC, identity, and internalizing difficulties. Specifically, APC…
Does daily distress make parents prone to using psychologically controlling parenting?
2016
The aim of the present study was to investigate whether parental daily distress in terms of negative emotions is associated with the daily variation in parental use of psychological control with their children. Whether parental positive emotions play a role in the use of psychological control was also investigated. The participants were 149 Finnish families with a child between the ages of 6 and 7 years. Parents’ negative and positive emotions, children’s misconduct, and parental use of psychological control when interacting with their children were measured daily using diary questionnaires filled in by the mothers and fathers over 7 successive days in the fall term of the children’s first…
Longitudinal associations between teacher-child interactions and academic skills in elementary school
2017
This study examined the extent to which the quality of teacher-child interactions assessed in kindergarten (6-year-olds) is associated with children's reading and math development across the elementary school years. The sample consisted of 515 Finnish children (271 boys, 244 girls). Teacher-child interactions were observed in 49 kindergarten classrooms. The findings from the latent growth curve models showed that high-quality teacher–child interactions in kindergarten were positively associated with the initial levels of reading and math skills. Furthermore, the results indicated that high-quality teacher-child interactions in kindergarten were positively associated with children's academic…
Do teachers’ professional vision and teaching experience always go hand in hand? Examining knowledge-based reasoning of Finnish Grade 1 teachers
2021
This mixed-method study explored 54 Finnish Grade 1 teachers' professional vision and teaching experience. Teachers' retrospective think-aloud interviews, conducted while watching their eye-tracking recordings of classroom actions, were analysed according to the domains of knowledge-based reasoning. Negative associations between teaching experience and amount of knowledge-based reasoning were found. The qualitative examination of three teachers with different amounts of teaching experience provided concrete examples and broadened the findings. We suggest that teachers’ knowledge-based reasoning should be seen not only as an ability that increases with experience but also as an ability that …
RAB18 Loss Interferes With Lipid Droplet Catabolism and Provokes Autophagy Network Adaptations
2020
Autophagy is dependent on appropriate lipid supply for autophagosome formation. The regulation of lipid acquisition and the autophagy network response to lipid-limiting conditions are mostly elusive. Here, we show that the knockout of the RAB GTPase RAB18 interferes with lipid droplet catabolism, causing an impaired fatty acid release. The resulting reduced lipid-droplet-derived lipid availability influences autophagy and provokes adaptive modifications of the autophagy network. These adjustments include increased expression and phosphorylation of ATG2B as well as augmented formation of the ATG12-ATG5 conjugate. Moreover, ATG9A shows an enhanced phosphorylation at amino acid residues tyrosi…
Activation of NF-kappaB and IL-8 by yersinia enterocolitica invasin protein is conferred by engagement of rac1 and MAP kinase cascades.
2003
International audience; Yersinia enterocolitica triggers activation of the nuclear factor (NF)-kappaB and production of the proinflammatory chemokine interleukin (IL)-8 in intestinal epithelial cells. This activation is due to adhesion of the bacteria via their outer membrane protein invasin to the host cells. Using Clostridium difficile toxins that specifically inactivate small GTPases, and transfection of inhibitory proteins of the Rho-GTPases, we demonstrate that Rac1, but not Cdc42 or Rho, is required for activation of NF-kappaB by invasin. Invasin activated the mitogen activated protein kinases (MAPK) p38 and c-Jun N-terminal protein kinase (JNK) but not extracellular signal regulated …
Enterobacter cloacae administration induces hepatic damage and subcutaneous fat accumulation in high-fat diet fed mice.
2018
Accumulating evidence indicates that gut microbiota plays a significant role in obesity, insulin resistance and associated liver disorders. Family Enterobacteriaceae and especially Enterobacter cloacae strain B29 have been previously linked to obesity and hepatic damage. The underlying mechanisms, however, remain unclear. Therefore, we comprehensively examined the effects of E. cloacae subsp. cloacae (ATCC® 13047™) administration on host metabolism of mice fed with high-fat diet (HFD). C57BL/6N mice were randomly divided into HFD control, chow control, and E. cloacae treatment groups. The E. cloacae treatment group received live bacterial cells in PBS intragastrically twice a week, every ot…