Search results for "40"
showing 10 items of 17345 documents
Modification of Angular Kinematics and Spatiotemporal Parameters during Running after Central and Peripheral Fatigue
2021
Fatigue causes kinematics modifications during running, and it could be related to injuries. The aim was to identify and compare the effects of central and peripheral fatigue on angular kinematics and spatiotemporal parameters during running. Angular kinematics and spatiotemporal parameters were evaluated using an infrared motion capture system and were registered during 2 min treadmill running in pre- and post-fatigue states in eighteen male recreational runners. Central fatigue was induced by a 30 min running fatigue protocol on a treadmill, while peripheral fatigue in quadriceps and hamstrings muscles was induced by an isokinetic dynamometer fatigue protocol. Central fatigue increased th…
Electrochemical detection and screening of bladder cancer recurrence using direct electrochemical analysis of urine: A non-invasive tool for diagnosis
2018
Although detection of urothelial cell carcinoma (or bladder cancer, BC) can be performed via cytological, molecular and genetic marker tests on urine, cystoscopy, an invasive technique, still remains as the gold methodology in clinical practice. It is presented a non-invasive method for detecting BC recurrence consisting of a direct electrochemical test in urine combining voltammetric data at gold and glassy carbon electrodes. The diagnosis is based on the ratio between characteristic voltammetric features recorded for tryptophan, serotonin and melatonin and other related metabolites. The method was tested by means of a clinical trial with 30 patients diagnosed of bladder cancer and a two c…
Isolation and confirmation of viral nervous necrosis (VNN) disease in golden grey mullet (Liza aurata) and leaping mullet (Liza saliens) in the Irani…
2016
The present study was conducted on 428 moribund mullet fish samples to isolate and identify the causative agent of a mysterious acute mortality which recently occurred in wild mullets in Iranian waters of Caspian Sea, suspected to be due to viral nervous necrosis (VNN) disease. Disease investigation was carried out employing various diagnostic procedures such as virology, bacteriology, parasitology, haematology, histopathology, IFAT, IHC and nested RT-PCR. Brain and eye samples of affected fishes were collected in sterile conditions and then kept at -80 °C for cell culture isolation and nested RT-PCR detection of the causative agent. Other tissue samples were also collected and fixed for hi…
Vulvo-vaginal atrophy: A new treatment modality using thermo-ablative fractional CO2 laser.
2015
a b s t r a c t Objective: To evaluate the efficacy and feasibility of thermo-ablative fractional CO2 laser for the treatment of symptoms related to vulvo-vaginal atrophy (VVA) in post-menopausal women. Methods: From April 2013 to December 2013, post-menopausal patients who complained of one or more VVA-related symptoms and who underwent vaginal treatment with fractional CO2 laser were enrolled in the study. At baseline (T0) and 30 days post-treatment (T1), vaginal status of the women was evaluated using the Vaginal Health Index (VHI), and subjective intensity of VVA symptoms was evaluated using a visual analog scale (VAS). At T1, treatment satisfaction was evaluated using a 5-point Likert …
The effect of conventional movement training and trampoline training on balance and gait in chronic hemiplegic patients
1991
The postural sway of subjects during standing both with their eyes open and closed together with maximum velocity of walking were analysed in six male chronic hemiplegic patients before, during and after an intensive movement training programme lasting 8 weeks. The movement training programme was carried out on the basis of Bobath's principles. Three of the subjects carried out their training on a trampoline, with the particular purpose of enhancing the stimulation of the mechanisms responsible for the control of balance. During the follow-up, maximal walking velocity remained at previous levels and no systematic changes were observed in the control of postural sway. Although the use of the…
Post-cesarean necrotizing fasciitis caused by surgical site infection
2017
Necrotizing fasciitis (NF) is a rare, but rapidly progressive, potentially life-threatening soft tissue infection, with an incidence of 0.15-0.55 cases per 100,000 population. the gynecological-obstetric literature describes cases of NF due to surgical site infection (SSi) after cesarean delivery. this article discusses issues in the medicolegal evaluation of NF and the importance of prophylactic procedures, risk management protocols, and prompt diagnosis of this condition. two cases of post-cesarean NF due to SSi are reported. in both cases the responsibility lay with the hospitals and the medical staff owing to failure to adopt adequate SSi prophylaxis and to establish a timely diagnosis …
Sentinel-node biopsy in early stage ovarian cancer: a prospective multicentre study (SELLY)
2019
BackgroundSystematic para-aortic and bilateral pelvic lymphadenectomy is included in the standard comprehensive surgical staging in presumed early epithelial ovarian cancer. No prospective randomized evidence suggests it has potential therapeutic value, and related morbidity is not negligible.Primary Objective(s)To assess sensitivity, safety, and feasibility of the sentinel lymph node technique in identifying the presence of lymph node metastases in patients with early stage epithelial ovarian cancer.Study HypothesisSentinel lymph node detection with indocyanine green can accurately predict nodal status in a cohort of women with early stage epithelial ovarian cancer.Trial DesignThe SELLY tr…
Obesity, Adipokines and Metabolic Syndrome in Polycystic Ovary Syndrome
2012
The complex mechanisms linking fat excess to metabolic syndrome are not well understood, but several experimental studies have shown that altered production of adipokines plays a main role in development and progression of this disorder. In particular, reduced secretion of adiponectin has a crucial role in inducing insulin resistance but also in determining the clustering of elevated triglycerides and small, dense LDL particles. Increased leptin secretion may be responsible for sympathetic nervous system overactivity and hypertension, while reduced omentin may have an important permissive role in the development of atherogenic processes. Finally, cytokines and other adipokines (resistin, vi…
Characteristics and patterns of care of endometrial cancer before and during COVID-19 pandemic
2021
Objective Coronavirus disease 2019 (COVID-19) outbreak has correlated with the disruption of screening activities and diagnostic assessments. Endometrial cancer (EC) is one of the most common gynecological malignancies and it is often detected at an early stage, because it frequently produces symptoms. Here, we aim to investigate the impact of COVID-19 outbreak on patterns of presentation and treatment of EC patients. Methods This is a retrospective study involving 54 centers in Italy. We evaluated patterns of presentation and treatment of EC patients before (period 1: March 1, 2019 to February 29, 2020) and during (period 2: April 1, 2020 to March 31, 2021) the COVID-19 outbreak. Results M…
The LDL receptor in the retina: the missing link in aging, the new target in dietary prevention
2012
National audience; Purpose: The discovery of the LDL receptor (LDLR) in 1985 by Brown and Goldstein was awarded by a Nobel Prize. The LDLR has initially been identified for its role in mediating the endocytosis of LDL particles in the vascular endothelium. The deposition of lipids, including cholesterol and cholesteryl esters in Bruch’s Membrane in the one hand, and in the vessel intima in the other hand, is one of the common features of age related macular degeneration (AMD) and cardiovascular disease (CVD). Dietary habits with high intakes of omega 3 long chain fatty acids (LCFA) have been associated with AMD prevention. Similar effects have been demonstrated in CVD prevention. The mechan…