Search results for "41"

Chemical Composition, In Vitro Bioaccessibility and Antioxidant Activity of Polyphenolic Compounds from Nutraceutical Fennel Waste Extract

2021

Fennel (Foeniculum vulgare Mill.) waste contains a broad range of bioactive molecules, including polyphenols, which have poor bioaccessibility during gastrointestinal digestion. This work aimed to investigate the bioaccessibility of total phenolic compounds and the antioxidant capacity during simulated gastrointestinal digestion using two nutraceutical formulations based on non-acid-resistant (NAR) and acid-resistant (AR) capsules containing aqueous-based extracts from fennel waste. Moreover, to obtain a comprehensive investigation of the polyphenolic constituents of the fennel waste extract, a high-resolution mass spectrometry (Q-Orbitrap) analysis was performed. Notably, chlorogenic acids…

Analysis of Phenolic Compounds in Commercial Cannabis sativa L. Inflorescences Using UHPLC-Q-Orbitrap HRMS

2020

Industrial hemp (Cannabis sativa L. Family Cannabaceae) contains a vast number of bioactive relevant compounds, namely polyphenols including flavonoids, phenolic acids, phenol amides, and lignanamides, well known for their therapeutic properties. Nowadays, many polyphenols-containing products made of herbal extracts are marketed, claiming to exert health-promoting effects. In this context, industrial hemp inflorescence may represent an innovative source of bioactive compounds to be used in nutraceutical formulations. The aim of this work was to provide a comprehensive analysis of the polyphenolic fraction contained in polar extracts of four different commercial cultivars (Kompoti, Tiborszal…

The Ancient Neapolitan Sweet Lime and the Calabrian Lemoncetta Locrese Belong to the Same Citrus Species

2019

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Pharmacokinetic Characterization and External Evaluation of a Quantitative Framework of Sublingual Buprenorphine in Patients with an Opioid Disorder …

2020

Background: The aim of this analysis was to characterize the pharmacokinetics (PK) of sublingual buprenorphine (BUP) and its metabolites (buprenorphine glucuronide

Oxidative stress in preterm infants: Overview of current evidence and future prospects

2020

Preterm birth (PTB), defined as parturition prior to 37 weeks of gestation, is the leading cause of morbidity and mortality in the neonatal population. The incidence and severity of complications of prematurity increase with decreasing gestational age and birthweight. The aim of this review study is to select the most current evidence on the role of oxidative stress in the onset of preterm complication prevention strategies and treatment options with pre-clinical and clinical trials. We also provide a literature review of primary and secondary studies on the role of oxidative stress in preterm infants and its eventual treatment in prematurity diseases. We conducted a systematic literature s…

Anti-proliferative effect of main dietary phytosterols and β-cryptoxanthin alone or combined in human colon cancer Caco-2 cells through cytosolic Ca+…

2015

β-cryptoxanthin (β-Cx) and phytosterols (Ps) have potential against different cancer types, including colon cancer. However, their combined action has not been reported so far. Human colon cancer Caco-2 cells were treated 24 h with β-Cx and/or main dietary Ps (β-sitosterol, campesterol and stigmasterol), alone or in combination, at concentrations compatible with physiological human serum levels. A decrease in cell viability due to apoptosis (rise in sub-G1 population and exposure of membrane phosphatidylserine) was accompanied with dephosphorylation of BAD, mitochondrial depolarization and caspase 3-dependent PARP cleavage, with intracellular Ca2+ influx and increase of RONS levels as initi…

International student mobility in Southern-Latin Europe: beyond the EU logics, towards a new space

2018

This paper discusses international student mobility (ISM) in Southern-Latin Europe, specifically Italy, Portugal, and Spain, analysing the inflow of international students as reflected in the UNESCO, OECD and European Commission databases. Only recently Italy, Portugal and Spain, as latecomers, have become more actively involved in ISM dynamics. This trend has been a response to EU pressures to internationalization, instrumented through the consolidation of the Bologna process and the need to build a common space of higher education. The analysis shows that at the intra-European level Italy, Portugal and Spain share similar ISM patterns; however, in the global context other logics shape ISM…

Power dispatching techniques as a finite state machine for a standalone photovoltaic system with a hybrid energy storage

2020

Standalone photovoltaic system (SPVS) is usually embedded with an energy storage unit to overcome the intermittency of photovoltaic (PV) generation as well as to address load variations in off-grid operation. In SPVS energy systems, batteries can serve as the long term energy storage and contributing to the large portion of the energy demand but to overcome the load intermittency, it necessitates a fast response energy storage embedded with the battery as a hybrid energy storage (HES) for dynamic loads (e.g., Electric Vehicle loads, emergency power management). In this work, Lead-Acid (LA) battery and supper capacitor (SC) array are used as the HES. HES helps not only in increasing more uti…

Vēsture: Latvijas Universitātes Žurnāls, 2018, Nr.5

2018

Imaginary Dialogues – In-service Teachers’ Steps Towards Mathematical Argumentation in Classroom Discourse

2018

The purpose of this qualitative study was to explore in-service teachers’ first experiences with imaginary dialogues – a form of mathematical writing where students are introduced to a written and unfinished dialogue between two imaginary persons discussing a mathematical problem. Students are supposed to continue working with the problem and to complete the initial dialogue between these persons. In-service teachers were enrolled in a continuing university education mathematics course. They were given the task to try out imaginary dialogues in their classes from grades 4 to 10. Based on in-service teachers’ responses in open-ended self-evaluation forms, the study examined how the in-servic…