Search results for "44"

The subtle balance of weak supramolecular interactions: The hierarchy of halogen and hydrogen bonds in haloanilinium and halopyridinium salts

2010

The series of haloanilinium and halopyridinium salts: 4-IPhNH3Cl (1), 4-IPhNH3Br (5), 4-IPhNH3H2PO4 (6), 4-ClPhNH3H2PO4 (8), 3-IPyBnCl (9), 3-IPyHCl (10) and 3-IPyH-5NIPA (3-iodopyridinium 5-nitroisophthalate, 13), where hydrogen or/and halogen bonding represents the most relevant non-covalent interactions, has been prepared and characterized by single crystal X-ray diffraction. This series was further complemented by extracting some relevant crystal structures: 4-BrPhNH3Cl (2, CCDC ref. code TAWRAL), 4-ClPhNH3Cl (3, CURGOL), 4-FPhNH3Cl (4, ANLCLA), 4-BrPhNH3H2PO4, (7, UGISEI), 3-BrPyHCl, (11, CIHBAX) and 3-ClPyHCl, (12, VOQMUJ) from Cambridge Structural Database for sake of comparison. Bas…

Herbalists, traditional healers and pharmacists: a view of the tuberculosis in Ghana

2014

This paper is the result of a visit by Brazilian researchers to Ghana, with the aim of improving understanding of the relationship between traditional healers and conventional health practices, specifically in relation to tuberculosis. Through this exploratory visit, this group of researchers promoted by the Edital Pro Africa (CNPq) had an opportunity to learn about, reflect on, and discuss the different social, economic and cultural realities and contexts that have led to the different health conditions and forms of healthcare in Ghana. Besides the direct relationship between the social and economic conditions of the country and the health of its population, it was also concluded that ther…

Drug-metabolizing enzyme activities in freshly isolated oval cells and in an established oval cell line from carcinogen-fed rats

1994

The activities of several different phase I and phase II drug-metabolizing enzymes were measured in freshly isolated oval cells from rats fed a choline-deficient/DL-ethionine-supplemented diet for 6 weeks and also in vitro in the established oval cell line OC/CDE 6. No cytochrome P450 was spectrophotometrically measurable in both preparations and two cytochrome P450-dependent monoxygenase activities, aminopyrine N-demethylase and ethoxyresorufin O-deethylase, could not be detected in the oval cells of both sources. However, cytosolic glutathione transferase, microsomal epoxide hydrolase and UDP-glucuronosyltransferase activities were clearly measurable in oval cells. Similar enzyme activiti…

Work-Related Stress, Physio-Pathological Mechanisms, and the Influence of Environmental Genetic Factors

2019

Work-related stress is a growing health problem in modern society. The stress response is characterized by numerous neurochemicals, neuroendocrine and immune modifications that involve various neurological systems and circuits, and regulation of the gene expression of the different receptors. In this regard, a lot of research has focused the attention on the role played by the environment in influencing gene expression, which in turn can control the stress response. In particular, genetic factors can moderate the sensitivities of specific types of neural cells or circuits mediating the imprinting of the environment on different biological systems. In this current review, we wish to analyze …

Healthy design and urban planning strategies, actions, and policy to achieve salutogenic cities

2018

Starting from a previous experience carried out by the working group “Building and Environmental Hygiene” of the Italian Society of Hygiene and Preventive Medicine (SItI), the aim of the present work is to define new strategic goals for achieving a “Healthy and Salutogenic City”, which will be useful to designers, local governments and public bodies, policy makers, and all professionals working at local health agencies. Ten key points have been formulated: 1. climate change and management of adverse weather events; 2. land consumption, sprawl, and shrinking cities; 3. tactical urbanism and urban resilience; 4. urban comfort, safety, and security perception; 5. strengths and weaknesses of ur…

Nuevas aportaciones al corpus pictórico valenciano del primer renacimiento: Rodrigo de Osona, Maestro de Perea, y Pere Cabanes I

2016

Analytic evaluation of the dipole Hessian matrix in coupled-cluster theory

2013

The general theory required for the calculation of analytic third energy derivatives at the coupled-cluster level of theory is presented and connected to preceding special formulations for hyperpolarizabilities and polarizability gradients. Based on our theory, we have implemented a scheme for calculating the dipole Hessian matrix in a fully analytical manner within the coupled-cluster singles and doubles approximation. The dipole Hessian matrix is the second geometrical derivative of the dipole moment and thus a third derivative of the energy. It plays a crucial role in IR spectroscopy when taking into account anharmonic effects and is also essential for computing vibrational corrections t…

A relativistically smeared spectrum in the neutron star X-ray binary 4U 1705−44: looking at the inner accretion disc with X-ray spectroscopy

2009

Iron emission lines at 6.4-6.97 keV, identified with fluorescent Kalpha transitions, are among the strongest discrete features in the X-ray band. These are therefore one of the most powerful probes to infer the properties of the plasma in the innermost part of the accretion disc around a compact object. In this paper we present a recent XMM observation of the X-ray burster 4U 1705-44, where we clearly detect a relativistically smeared iron line at about 6.7 keV, testifying with high statistical significance that the line profile is distorted by high velocity motion in the accretion disc. As expected from disc reflection models, we also find a significant absorption edge at about 8.3 keV; th…

Testing reflection features in 4U 1705-44 with XMM-Newton, BeppoSAX, and RXTE in the hard and soft states

2012

We use data of the bright atoll source 4U 1705-44 taken with XMM-Newton, BeppoSAX and RXTE both in the hard and in the soft state to perform a self-consistent study of the reflection component in this source. Although the data from these X-ray observatories are not simultaneous, the spectral decomposition is shown to be consistent among the different observations, when the source flux is similar. We therefore select observations performed at similar flux levels in the hard and soft state in order to study the spectral shape in these two states in a broad band (0.1-200 keV) energy range, with good energy resolution, and using self-consistent reflection models. These reflection models provide…

The spin and orbit of the newly discovered pulsar IGR J17480-2446

2011

We present an analysis of the spin and orbital properties of the newly discovered accreting pulsar IGR J17480-2446, located in the globular cluster Terzan 5. Considering the pulses detected by the Rossi X-ray Timing Explorer at a period of 90.539645(2) ms, we derive a solution for the 21.27454(8) hr binary system. The binary mass function is estimated to be 0.021275(5) Msun, indicating a companion star with a mass larger than 0.4 Msun. The X-ray pulsar spins up while accreting at a rate of between 1.2 and 1.7E-12 Hz/s, in agreement with the accretion of disc matter angular momentum given the observed luminosity. We also report the detection of pulsations at the spin period of the source dur…