Search results for "48"
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L’art. 8 della legge n. 148 del 2011 nel sistema delle relazioni sindacali
2012
Il saggio analizza i principali profili problematici sottesi alla disciplina della contrattazione di prossimità. Segnatamente, vengono esaminati i rapporti tra l'art. 8 della l. n. 148/2011 e le regole sulla rappresentanza e sui rapporti tra livelli di contrattazione previste dall'ordinamento intersindacale. In tale prospettiva, l'Autore si sofferma altresì sui dubbi di legittimità costituzionale legati all'estensione dell'efficacia soggettiva dei contratti collettivi aziendali in deroga, sulla base di un meccanismo che parrebbe in contrasto con l'art. 39 Cost. Perplessità vengono sollevate anche con riferimento alla compatibilità della disposizione l'art. 3 della Costituzione, atteso che l…
Heijastavatko työn ja perheen yhteensovittamisen kokemukset yksilön elämänarvoja?
2014
Tässä tutkimuksessa tarkasteltiin yksilön elämänarvojen yhteyttä työn ja perheen välisen ristiriidan ja rikastavuuden kokemuksiin. Analyysit perustuivat 50-vuotiaisiin Lapsesta aikuiseksi - pitkittäistutkimuksen osanottajiin (n = 156, 53 % miehiä). Schwartzin (1992) menetelmällä tarkastellut elämänarvot olivat hyväntahtoisuus, universalismi, turvallisuus, yhdenmukaisuus, hedonismi, itseohjautuvuus, suoriutuminen, stimulaatio, traditiot ja valta. Suoriutuminen ja universalismi olivat myönteisesti yhteydessä sekä työn ja perheen välisen ristiriidan että rikastavuuden kokemuksiin. Sen sijaan stimulaatio oli myönteisesti yhteydessä vain ristiriidan ja yhdenmukaisuus vain rikastavuuden kokemuksi…
Type 1 Diabetes and Autoimmune Thyroid Disease—The Genetic Link
2021
Type 1 diabetes (T1D) and autoimmune thyroid disease (AITD) are the most frequent chronic autoimmune diseases worldwide. Several autoimmune endocrine and non-endocrine disorders tend to occur together. T1D and AITD often cluster in individuals and families, seen in the formation of autoimmune polyendocrinopathy (AP). The close relationship between these two diseases is largely explained by sharing a common genetic background. The HLA antigens DQ2 (DQA1*0501-DQB1*0201) and DQ8 (DQA1*0301-DQB1*0302), tightly linked with DR3 and DR4, are the major common genetic predisposition. Moreover, functional single nucleotide polymorphisms (or rare variants) of various genes, such as the cytotoxic T-lym…
Zaudējuma atlīdzības jēdziens un prakse intelektuālā īpašuma tiesības pēc direktīvas Nr. 2004/48/EK ieviešanas
2017
Bakalaura darbs vērsts, galvenokārt, uz “Eiropas Parlamenta un Padomes Direktīvā Nr.2004/48/EK par intelektuālā īpašuma tiesību piemērošanu likumdošanā” paredzēto kaitējuma atlīdzības veidu teorētisko un praktisko izpēti. Darbā aplūkota gan Latvijas Republikas, gan Eiropas Savienības Tiesas prakse pēc Eiropas Parlamenta un Padomes Direktīvas Nr.2004/48/EK ieviešanas sakarā ar preču zīmju un autortiesību īpašnieku tiesību pārkāpumiem. Autore darbā izdarījusi vairākus priekšlikumus par nepieciešamajām izmaiņām normatīvajos aktos, lai intelektuālā īpašuma pārkāpuma gadījumos tiesību īpašniekiem būtu pieejama iespēja saņemt atlīdzību par nodarīto kaitējumu.
Strengthening of Masonry Columns with BFRCM or with Steel Wires: An Experimental Study
2016
Nowadays, innovative materials are more frequently adopted for strengthening historical constructions and masonry structures. The target of these techniques is to improve the structural efficiency with retrofitting methods while having a reduced aesthetical impact. In particular, the use of basalt fiber together with a cementitious matrix emerges as a new technique. This kind of fiber is obtained by basalt rock without other components, and consequently it could be considered a natural material, compatible with masonry. Another innovative technique for strengthening masonry columns consists of applying steel wires in the correspondence of mortar joints. Both techniques have been recently pr…
Pave Frans – bedring, men ingen løsning for en kirke i krise
2020
Kritiske ytringer om pave Frans framsettes som regel på konservativt og tradisjonalistisk katolsk hold. Denne artikkelen sikter på å presentere en progressivt fundert kritikk av det nåværende pontifikatet. Frans krediteres for gode intensjoner, pastoralt lederskap og motstand mot klerikalistiske holdninger. Men da han ikke har maktet – og kanskje heller ikke tilstrekkelig klart ønsket – å endre kirkens utdaterte hierarkiske struktur, er han ingen løsning på de store utfordringene Den katolske kirke lenge har stått overfor. Artikkelen har et aktuelt og kritisk sikte, og den preges i større grad av normative vurderinger enn mange andre faglige bidrag i dag.
On the fermentative behavior of auxotrophic strains of Saccharomyces cerevisiae
2014
Background: The selection of new yeast strains could lead to improvements in bioethanol production. Here, we have studied the fermentative capacity of different auxotrophic mutants of Saccharomyces cerevisiae, which are routinely used as hosts for the production of heterologous proteins. It has recently been found that these strains exhibit physiological alterations and peculiar sensitivities with respect to the parental prototrophic strains from which they derive. In this work the performance of auxotrophic S. cerevisiae CEN.PK strains was compared to the corresponding prototrophic strain, to S. cerevisiae T5bV, a strain isolated from grape must and to another auxotrophic strain, S. cerevi…
Plazmas miRNS kā multiplās sklerozes biomarķieri
2018
Vairākos pētījumos ir atklātas miRNS, tajā skaitā cirkulējošas miRNS, kuru daudzums ir izmainīts multiplā sklerozē. miRNS kā jaunu biomarķieru izpēte šai slimībai varētu palīdzēt diagnosticēt un prognozēt tās attīstību agrīnā stadijā. Šajā pētījumā ir prezentēti mūsu dati par dažām miRNS, kas tikadetektētas MS pacientu asins plazmā, kā izmainītas. Mēs salīdzinājām miRNS ekspresijas līmeņus MS un tās apakštipos ar veselo kontroli, lai atrastu potenciālās miRNS, kas var tikt izmantotas, kā MS biomarķieri. Galvenais mērķis bija validēt sekvenēšanas rezultātā atlasītās miRNS, kuru daudzums bija izmainīts MS pacientu asins plazmā neatkarīgā pacientu kopā. miRNS 484, kuras daudzums bija visvairāk…
Comparison between two different cardiovascular models during a hemorrhagic shock scenario
2020
Hemorrhagic shock is a form of hypovolemic shock determined by rapid and large loss of intravascular blood volume and represents the first cause of death in the world, whether on the battlefield or in civilian traumatology. For this, the ability to prevent hemorrhagic shock remains one of the greatest challenges in the medical and engineering fields. The use of mathematical models of the cardiocirculatory system has improved the capacity, on one hand, to predict the risk of hemorrhagic shock and, on the other, to determine efficient treatment strategies. In this paper, a comparison between two mathematical models that simulate several hemorrhagic scenarios is presented. The models considere…
Case Report: Insulinoma Presenting as Excessive Daytime Somnolence
2021
Currently, undiagnosed insulinomas remain a difficult clinical dilemma because its symptoms in most cases can easily be misdiagnosed as other diseases. In this article, we present the case of a 14-year-old girl who presented to our hospital with recurrent episodes of excessive daytime sleepiness and abnormal behavior during sleep that had been going on for 3 months. Insulinoma is a rare neuroendocrine tumor that causes excessive release of insulin, resulting in episodes of hypoglycemia. It usually manifests as autonomic sympathetic symptoms. These symptoms resolved rapidly with the administration of glucose. After successful removal of the tumor, daytime sleepiness and abnormal nighttime be…